Computational Biology and Bioinformatics: Gene Regulation, Ka-Chun Wong
Название: Computational systems bioinformatics - methods and biomedical applications ISBN: 9812707042 ISBN-13(EAN): 9789812707048 Издательство: World Scientific Publishing Рейтинг: Цена: 100320.00 T Наличие на складе: Невозможна поставка. Описание: Computational systems biology (CSB) is a field of research concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. This book introduces the basic principles of CSB.
Автор: Gautam B. Singh Название: Fundamentals of Bioinformatics and Computational Biology ISBN: 3319383132 ISBN-13(EAN): 9783319383132 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolbox™. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today’s biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.
Автор: Florentino Fdez-Riverola; Miguel Rocha; Mohd Saber Название: Practical Applications of Computational Biology and Bioinformatics, 13th International Conference ISBN: 3030238725 ISBN-13(EAN): 9783030238728 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book features 21 papers spanning many different sub-fields in bioinformatics and computational biology, presenting the latest research on the practical applications to promote fruitful interactions between young researchers in different areas related to the field. Next-generation sequencing technologies, together with other emerging and diverse experimental techniques, are evolving rapidly, creating numerous types of omics data. These, in turn, are creating new challenges for the expanding fields of bioinformatics and computational biology, which seek to analyse, process, integrate and extract meaningful knowledge from such data. This calls for new algorithms and approaches from fields such as databases, statistics, data mining, machine learning, optimization, computer science, machine learning and artificial intelligence. Clearly, biology is increasingly becoming a science of information, requiring tools from the computational sciences. To address these challenges, we have seen the emergence of a new generation of interdisciplinary scientists with a strong background in the biological and computational sciences. In this context, the interaction of researchers from different scientific areas is, more than ever, vital to boost the research efforts in the field and contribute to the training of the new generation of interdisciplinary scientists.
Автор: Juan Manuel Corchado Rodr?guez; Francisco de Paz; Название: 2nd International Workshop on Practical Applications of Computational Biology and Bioinformatics (IWPACBB 2008) ISBN: 3540858601 ISBN-13(EAN): 9783540858607 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: New global approaches, such as Systems Biology, have been emerging replacing the reductionist view that dominated biology research in the last decades, requiring the coordinated efforts of biological researchers with those related to data analysis, mathematical modelling and computer science.
Автор: Liwo Adam Название: Computational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes: From Bioinformatics to Molecular Quantum Mechani ISBN: 3319958429 ISBN-13(EAN): 9783319958422 Издательство: Springer Рейтинг: Цена: 232910.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides a comprehensive overview of modern computer-based techniques for analyzing the structure, properties and dynamics of biomolecules and biomolecular processes. It is organized in four main parts; the first one deals with methodology of molecular simulations; the second one with applications of molecular simulations; the third one introduces bioinformatics methods and the use of experimental information in molecular simulations; the last part reports on selected applications of molecular quantum mechanics. This second edition has been thoroughly revised and updated to include the latest progresses made in the respective field of research.
Автор: Dariusz Mrozek Название: High-Performance Computational Solutions in Protein Bioinformatics ISBN: 3319069705 ISBN-13(EAN): 9783319069708 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This work focuses on proteins and their structures, protein structure similarity searching at main representation levels and various techniques that can be used to accelerate similarity searches.
Автор: Nikolay Kolchanov; Ralf Hofestaedt; Luciano Milane Название: Bioinformatics of Genome Regulation and Structure II ISBN: 1461497701 ISBN-13(EAN): 9781461497707 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The last 15 years in development of biology were marked with accumulation of unprecedentedly huge arrays of experimental data. The information was amassed with exclusively high rates due to the advent of highly efficient experimental technologies that provided for high throughput genomic sequencing; of functional genomics technologies allowing investigation of expression dynamics of large groups of genes using expression DNA chips; of proteomics methods giving the possibility to analyze protein compositions of cells, tissues, and organs, assess the dynamics of the cell proteome, and reconstruct the networks of protein-protein interactions; and of metabolomics, in particular, high resolution mass spectrometry study of cell metabolites, and distribution of metabolic fluxes in the cells with a concurrent investigation of the dynamics of thousands metabolites in an individual cell. Analysis, comprehension, and use of the tremendous volumes of experimental data reflecting the intricate processes underlying the functioning of molecular genetic systems are unfeasible in principle without the systems approach and involvement of the state-of-the-art information and computer technologies and efficient mathematical methods for data analysis and simulation of biological systems and processes. The need in solving these problems initiated the birth of a new science— postgenomic bioinformatics or systems biology in silico.
Название: Regulation of Gene Expression by Small RNAs ISBN: 1138111732 ISBN-13(EAN): 9781138111738 Издательство: Taylor&Francis Рейтинг: Цена: 76550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
New Findings Revolutionize Concepts of Gene Function
Endogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 percent of gene expression.
Regulation of Gene Expression by Small RNAs brings together the pioneering work of researchers who discuss their work involving a wide variety of small RNA regulatory pathways in organisms ranging from bacteria to humans. In addition to exploring the biogenesis and processing of these regulatory RNAs, they also consider the functional importance of these pathways in host organisms. Assisting current and future researchers, this unique groundbreaking work --
Provides a suite of cutting-edge resources for the study of microRNA ontology and function
Includes a technology guide for those seeking to assay microRNA expression
Explores the mechanisms by which microRNAs regulate gene expression in animal cells, including the regulation of gene expression by RNA-mediated transcriptional gene silencing
Discusses a fast and low-cost approach for reversing genetic influences in mammals
Looks at breakthroughs in the use of microRNA-based therapy for HIV and cancer
This volume captures the essence of the breadth and excitement surrounding the newly discovered regulatory roles of small RNAs. The powerful new approach in the study of gene function described in this text is leading to some remarkable findings that have the potential to revolutionize our understanding of genetic function and the treatment of diseases otherwise considered intractable.
Автор: Ashwani Kumar Название: Essential Bioinformatics ISBN: 168094522X ISBN-13(EAN): 9781680945225 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 141370.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Traditionally biological studies examined individual systems in detail, and compared them with a few that were related. In bioinformatics, we can now conduct global analyses of all the available data with the aim of uncovering common principles that apply across many systems and highlight novel feature.
Автор: Yongxian Wang, Zhenghua Wang Название: Proteomics and Biological Networks ISBN: 311046117X ISBN-13(EAN): 9783110461176 Издательство: Walter de Gruyter Цена: 148700.00 T Наличие на складе: Нет в наличии. Описание: This book presents molecular biology knowledge and mathematical theories of frequently-used algorithms in sequence comparison, gene finding, sequence evolution and structuring phylogenetic tree.
Автор: Arpad Kelemen; Ajith Abraham; Yuehui Chen Название: Computational Intelligence in Bioinformatics ISBN: 364209550X ISBN-13(EAN): 9783642095504 Издательство: Springer Рейтинг: Цена: 181670.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Bioinformatics involve the creation and advancement of algorithms using techniques including computational intelligence, applied mathematics and statistics, informatics, and biochemistry to solve biological problems usually on the molecular level.
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