Conditional Mutagenesis: An Approach to Disease Models, Robert Feil; Daniel Metzger

Автор: Monica Justice; Mary Bedell
Название: Mutagenesis of the Mouse Genome
ISBN: 9401751048 ISBN-13(EAN): 9789401751049
Издательство: Springer
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Автор: M. Bauchinger; G?nter Obe; F.K. Ennever; H. Hayats
Название: Advances in Mutagenesis Research
ISBN: 3642749577 ISBN-13(EAN): 9783642749575
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Описание: The new field of applied genetic research, genetic toxicology and mutation research investigates the mutagenicity and cancerogenicity of chemicals and other agents.

Автор: W. Generoso
Название: DNA Repair and Mutagenesis in Eukaryotes
ISBN: 1468438441 ISBN-13(EAN): 9781468438444
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Описание: Not many years ago most discussion of mutation induction by physical and chemical agents concentrated on the initial lesions induced in the DNA with the implicit assumption that once the lesions were made they were converted almost automatically to mutations by relatively simple processes associated with DNA replication.

Автор: Y.F. Bogdanov; E. Dikomey; N.A. Liapunova; W.-U. M
Название: Advances in Mutagenesis Research
ISBN: 3642781950 ISBN-13(EAN): 9783642781957
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Описание: Applied genetic research, genetic toxicology and mutation research investigate the mutagenicity of chemicals and other agents. Permanent mutation in genes and chromosomes can be induced by a plethora of agents, including ionizing and nonionizing radiations, chemicals, and viruses.

Автор: G?nter Obe; H.H. Evans; D. Frankenberg; M. Franken
Название: Advances in Mutagenesis Research
ISBN: 3642762344 ISBN-13(EAN): 9783642762345
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Описание: Applied genetic research, genetic toxicology and mutation research investigate the mutagenicity and cancerogenicity of chemicals and other agents.

Автор: Greg Davis; Kevin J. Kayser
Название: Chromosomal Mutagenesis
ISBN: 161737833X ISBN-13(EAN): 9781617378331
Издательство: Springer
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Цена: 111790.00 T
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Описание: In Chromosomal Mutagenesis, a team of experts provide a variety of chromosomal manipulation techniques, including insertional gene disruptions, gene knockouts, stimulated homologous recombination techniques and other novel tools, for both prokaryotic and eukaryotic organisms, and attempt to expand the genetic toolbox beyond model organisms.

Автор: Jeff Braman
Название: In Vitro Mutagenesis Protocols
ISBN: 1493956663 ISBN-13(EAN): 9781493956661
Издательство: Springer
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Цена: 130430.00 T
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Описание: In the post-genomic era, in vitro mutagenesis has emerged as a critically important tool for establishing the functions of components of the proteome. The third edition of In Vitro Mutagenesis Protocols represents a practical toolbox containing protocols vital to advancing our understanding of the connection between nucleotide sequence and sequence function. Fully updated from the previous editions, this volume contains a variety of specialty tools successfully employed to unravel the intricacies of protein-protein interaction, protein structure-function, protein regulation of biological processes, and protein activity, as well as a novel section on mutagenesis methods for unique microbes as a guide to the generalization of mutagenesis strategies for a host of microbial systems. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, In Vitro Mutagenesis Protocols, Third Edition offers today's researchers a valuable compendium of reliable and powerful techniques with which to illuminate the proteome and its rich web of biological implications.

Автор: David Mittelman
Название: Stress-Induced Mutagenesis
ISBN: 1489994181 ISBN-13(EAN): 9781489994189
Издательство: Springer
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Цена: 174130.00 T
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Описание: This book covers pathways of stress-induced mutagenesis, which may yield models for genome instability underlying some cancers and genetic diseases, resistance to chemotherapeutic and antibiotic drugs, pathogenicity of microbes, and other important processes.

Автор: A. Muhammed
Название: Basic and Applied Mutagenesis
ISBN: 1468449788 ISBN-13(EAN): 9781468449785
Издательство: Springer
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Цена: 113190.00 T
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Описание: These are the same chemicals that are in use throughout the develop- ing world, although the quantities of the different types that are used may vary from country to country, and from region to region within countries.

Автор: Johannes Horst Schr?der
Название: Genetics and Mutagenesis of Fish
ISBN: 3642657028 ISBN-13(EAN): 9783642657023
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Цена: 139310.00 T
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Описание: The present volume contains papers presented on the occasion of the Ichthyological Symposium on Genetics and Mutagenesis held on October 13 through 15, 1972 at the Biology Institute of the Association for Radia- tion and Environmental Research in Neuherberg near Munich, Germany. These symposia have been held annually since 1955 by former students of Prof. C. Kosswig and Prof. F. Anders in Hamburg or Giessen. In the last two years attendance has increased beyond the national German basis, but the Neuherberg meeting of fish geneticists was the first that could be called "international," the participants coming from twelve different countries. The organization of this meeting was made possible by the support of the Association for Radiation and Environmental Research, which provided the financial backing; special thanks are due to Min.- Rat. H. Costa and Dr. R. Wittenzellner. The scientific advice and encouragement of the Director of the Biology Institute, Prof. O. Hug, was also much appreciated, as was the helpful assistance of Dr. B. Betz and Dr. K. Gottel. In addition, I have to thank my colleagues and co- workers Mdmes. E. Neubner, I.S. Otten, and K. Peters, Messrs. M. Murr and M. Wiestner, and Dr. S. Holzberg for their help in organizing the meeting. Apart from the papers presented at the above symposium, we have in- cluded some papers by colleagues who were unable to attend the meeting.

Автор: G?nter Obe; F. Cortes; P. Escalza; A. Hofmann; V.I
Название: Advances in Mutagenesis Research
ISBN: 3642774687 ISBN-13(EAN): 9783642774683
Издательство: Springer
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Автор: Shondra M. Pruett-Miller
Название: Chromosomal Mutagenesis
ISBN: 1493918613 ISBN-13(EAN): 9781493918614
Издательство: Springer
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Цена: 139750.00 T
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Описание: This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols.