Dementia in Parkinsonism, Susan E. Daniel; Felix F. Cruz-Sanchez; Andrew J.

Автор: Cristina Sampaio, Christopher G. Goetz...
Название: Rating Scales in Parkinson`s Disease Clinical Practice and Research
ISBN: 0199783101 ISBN-13(EAN): 9780199783106
Издательство: Oxford Academ
Рейтинг:
Цена: 81310.00 T
Наличие на складе: Есть
Описание: Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one convenient source. Until now. Rating Scales in Parkinson's Disease: Clinical Practice and Research is written for researchers from the medical and social sciences, and for health professionals wishing to evaluate the progress of their patients suffering from Parkinson's Disease. The book is both exhaustive in the description of the scales and informative on the advantages and limitations of each scale. As such, the text clearly guides readers on how to choose and use the instruments available. Extensive cross-referenced tables and charts closely integrate the parts of the book to facilitate readers in moving from one symptom domain to another. Features Based on a consistent and uniform methodology A clear consolidation of material otherwise only available in journals The first comprehensive book of its kind

Автор: Ronald F. Pfeiffer
Название: Parkinson`s Disease, Second Edition
ISBN: 1439807140 ISBN-13(EAN): 9781439807149
Издательство: Taylor&Francis
Рейтинг:
Цена: 214370.00 T
Наличие на складе: Нет в наличии.
Описание: In recent years, considerable advances have been made in our knowledge and understanding of Parkinson's disease (PD). In particular, there has been an explosion of information regarding genetic contributions to the etiology of PD and an increased awareness of the incidence and importance of the non-motor features of the disease. Theories regarding the pathogenesis and pathophysiology of PD have also been refined, and new treatment modalities and advances have been implemented. Reflecting these changes, this second edition features new chapters devoted to genetic aspects of PD, non-motor features of the disease, as well as aspects of the pathophysiology, pathogenesis, and treatment of PD.

Автор: J. Marks
Название: The Treatment of Parkinsonism with L-Dopa
ISBN: 9401572321 ISBN-13(EAN): 9789401572323
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: Edwards Mark
Название: Parkinson`s Disease and Other Movement Disorders
ISBN: 0198705069 ISBN-13(EAN): 9780198705062
Издательство: Oxford Academ
Рейтинг:
Цена: 70750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book allows the movement disorder clinician or therapist access to concise, practical, comprehensive and expert information on movement disorder diagnosis and treatment, in a convenient handbook form.

Автор: Galvez-Jimenez
Название: Parkinson`s Disease
ISBN: 1107053862 ISBN-13(EAN): 9781107053861
Издательство: Cambridge Academ
Рейтинг:
Цена: 109830.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book emphasizes treatment options for Parkinson`s disease, critically assessing pharmacologic and surgical interventions. Evidence from randomized controlled clinical trials is highlighted to develop practical recommendations for clinical practice. Readers will find the necessary clinical and scientific foundations for the understanding of the disease and the basis for solid therapeutics.

Автор: Joseph Jankovic,,Eduardo Tolosa
Название: Parkinson`s Disease and Movement Disorders
ISBN: 1608311767 ISBN-13(EAN): 9781608311767
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 243670.00 T
Наличие на складе: Невозможна поставка.
Описание: Trusted as the leading text in the field, Parkinson's Disease and Movement Disorders, 6th Edition, brings you fully up to date with new developments in this rapidly-changing subspecialty.  International experts provide thorough coverage of basic science and clear guidance for your day-to-day clinical challenges – from innovative medical and surgical treatments to new drug delivery systems and recent discoveries in genetics, plus much more.  In addition, an extensive online video atlas demonstrates movement and posture abnormalities, as well as unique and unusual phenomenology.Get comprehensive, current information on every aspect (including behavioral and psychologic concomitants) of all common and uncommon movement disorders, including Parkinson's disease, other neurodegenerative diseases, tremors, dystonia, Tourette's syndrome, Huntington's disease, and ataxias.Focus on the new discoveries you need to know about: the role of ubiquitin-proteosome and autophagy systems in neurodegeneration; genetics of Parkinson’s disease and other movement disorders; innovative medical and surgical treatment of Parkinson’s disease and hyperkinetic movement disorders; and more.Stay up to date with new information on autoimmune disorders, novel deliveries of drugs, and new formulations of botulinum toxin.Benefit from access to an outstanding online video library (with dozens of new videos) that demonstrate what you’re likely to see in practice and key elements to look for.Instantly view videos online with your tablet or smartphone, thanks to new QR codes inserted throughout the text.Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to:Dozens of videos that demonstrate the movement and posture abnormalities and other disturbances associated with Parkinson's disease and other neurologic disorders.Complete content with enhanced navigation.Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web.Cross-linked pages, references, and more for easy navigation.Highlighting tool for easier reference of key content throughout the text.Ability to take and share notes with friends and colleagues.Quick reference tabbing to save your favorite content for future use.

Автор: Jack R. Jr. Lancaster; J.F. Parkinson
Название: Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones
ISBN: 3662035057 ISBN-13(EAN): 9783662035054
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The discovery of mammalian nitric oxide (NO-) synthesis from I-ar- ginine has led to profound increases in our understanding of basic physiological and pathophysiological processes. This understanding has been achieved by major advances in several areas. Three major ni- tric oxide synthase (NOS) isoforms have been identified at the protein and gene level and their specific tissue localization has been linked to processes subject to regulation by NO-. The molecular basis for the di- verse effects of NO- on cell function has been shown to derive from its chemical reactivity with oxygen-containing species and both heme and non-heme iron-dependent enzymes. The potential regulation of heme- dependent enzymes such as cytochromes P450, guanylate cyclase, cy- clooxygenase, and mitochondrial cytochrome oxidase continues to emerge as a key area in NO- research. In addition, it has become clear that the expression of NOS isoforms and NO- release from cells is subject to regulation by sexual steroids and that, in tum, NO- has the potential to regulate steroid biosynthesis via inhibition of cytochromes P450 involved in steroidogenesis. These recent observations on interactions between the NO-/NOS and cytochrome P450/sexual steroid pathways have important implica- tions for understanding fundamental mechanisms involved in endocri- nological processes. They are also likely to lead to novel insights and novel therapeutic approaches for the management of pathophysiologi- cal conditions associated with alterations in sexual steroid hormones.

Автор: Peter Riederer; Horst Przuntek
Название: Morbus Parkinson Selegilin (R-(—)-Deprenyl); Movergan®
ISBN: 3211820329 ISBN-13(EAN): 9783211820322
Издательство: Springer
Рейтинг:
Цена: 81050.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Internationales Parkinson-Symposium, Berlin, 23. bis 25. Januar 1987

Автор: Buhlman
Название: Mitochondrial Mechanisms of Degeneration and Repair in Parkinson`s Disease
ISBN: 3319421379 ISBN-13(EAN): 9783319421377
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson’s disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are involved in specific functions as attractive therapeutic targets. It is expected to facilitate critical thought and discussion about the fundamental aspects of neurodegeneration in Parkinson’s disease and foster the development of therapeutic strategies among researchers and graduate students. Theories of idiopathic Parkinson’s etiology support roles for chronic inflammation and exposure to heavy metals or pesticides. Interestingly, as this project proposes, a case can be made that abnormalities in mitochondrial morphology and function are at the core of each of these theories. In fact, the most common approach to the generation of animal and cell-culture models of idiopathic Parkinson’s disease involves exposure to mitochondrial toxins. Even more compelling is the fact that most familial patients harbor genetic mutations that cause disruptions in normal mitochondrial morphology and function. While there remains to be no effective treatment for Parkinson’s disease, efforts to postpone, prevent and “cure” onset mitochondrial aberrations and neurodegeneration associated with Parkinson’s disease in various models are encouraging. While only about ten percent of Parkinson’s patients inherit disease-causing mutations, discovering common mechanisms by which familial forms of Parkinson’s disease manifest will likely shed light on the pathophysiology of the more common idiopathic form and provide insight to the general process of neurodegeneration, thus revealing therapeutic targets that will become more and more accessible as technology improves.

Автор: Colosimo
Название: Handbook of Atypical Parkinsonism
ISBN: 0521111978 ISBN-13(EAN): 9780521111973
Издательство: Cambridge Academ
Рейтинг:
Цена: 98210.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Neurologists are increasingly faced with atypical parkinsonian disorders, which mimic Parkinson`s disease but can be difficult to diagnose. This authoritative guide covers basic science, differential diagnosis, treatment and future research directions. Clinicians in neurology will find this book essential for understanding and diagnosing this complex group of disorders.