Novel Technologies for Vaccine Development, Igor S Lukashevich; Haval Shirwan
Автор: Igor S Lukashevich; Haval Shirwan Название: Novel Technologies for Vaccine Development ISBN: 3709118174 ISBN-13(EAN): 9783709118177 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.
Автор: Koff Название: Vaccine Research and Development ISBN: 082478619X ISBN-13(EAN): 9780824786199 Издательство: Taylor&Francis Рейтинг: Цена: 244990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Reviews advances in immunization research and addresses scientific and public policy challenges for moving candidate vaccines from the laboratory to the population. This title analyzes the capacity of lipophilic components to chemically modify peptide and protein antigens and augment their immunogenicity.
Автор: Manmohan Singh Название: Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines ISBN: 1489992286 ISBN-13(EAN): 9781489992284 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book outlines the critical steps that need to be considered for successful development of various types of nanoparticulate delivery systems for vaccine antigens. Coverage includes clinical evaluations with these novel vaccine technologies.
Автор: Alejandro Brun Название: Vaccine Technologies for Veterinary Viral Diseases ISBN: 1493950002 ISBN-13(EAN): 9781493950003 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
1. Vaccines and Vaccination for Veterinary Viral Diseases: A General Overview
Alejandro Brun
2. Using IC-Tagging Methodology for Production and Purification of Epitope-Loaded Protein Microspheres for Vaccination
Natalia Barreiro-Piсeiro, Rebeca Menaya-Vargas, Alberto Brandariz-Nъсez; Iria Otero-Romero, Irene Lostalй-Seijo, Javier Benavente, and Josй M. Martнnez-Costas
3. Plant-Based Vaccine Antigen Production
Hoang Trong Phan and Udo Conrad
4. DNA Vaccines: Experiences in the Swine Model
Francesc Accensi, Fernando Rodrнguez, and Paula L. Monteagudo
5. Novel Adjuvants and Immunomodulators for Veterinary Vaccines
Peter M.H. Heegaard, Yongxiang Fang, and Gregers Jungersen
6. Polymerase Mechanism-Based Method of Viral Attenuation
Cheri A. Lee, Avery August, Jamie J. Arnold, and Craig E. Cameron
7. BacMam Platform for Vaccine Antigen Delivery
Gьnther M. Keil, Reiko Pollin, Claudia Mьller, Katrin Giesow, and Horst Schirrmeier
8. Laboratory-Scale Production of Replication-Deficient Adenovirus Vectored Vaccines
Susan J. Morris, Alison V. Turner, Nicola Green, and George M. Warimwe
9. Generation of Recombinant Modified Vaccinia Virus Ankara Encoding VP2, NS1, and VP7 Proteins of Bluetongue Virus
Alejandro Marнn-L
уpez and Javier Ortego
10. Generation of Recombinant Capripoxvirus Vectors for Vaccines and Gene Knockout Function Studies
Hani Boshra, Jinxing Cao, and Shawn Babiuk
11. Recombinant Swinepox Virus for Veterinary Vaccine Development
Hong-Jie Fan and Hui-Xing Lin
12. Generation and Selection of Orf Virus (ORFV) Recombinants
Hanns-Joachim Rziha, Jцrg Rohde, and Ralf Amann
13. Polycistronic Herpesvirus Amplicon Vectors for Veterinary Vaccine Development
Anita Felicitas Meier, Andrea Sara Laimbacher, and Mathias Ackermann
14. Construction and Application of Newcastle Disease Virus-Based Vector Vaccines
Paul J. Wichgers Schreur
15. Chimeric Pestivirus Experimental Vaccines
Ilona Reimann, Sandra Blome, and Martin Beer
16. Analysis of the Cellular Immune Responses to Vaccines
Nicholas Svitek, Evans L.N. Taracha, Rosemary Saya, Elias Awino, Vish Nene, and Lucilla Steinaa
Автор: Stanley A. Plotkin Название: History of Vaccine Development ISBN: 1489993576 ISBN-13(EAN): 9781489993571 Издательство: Springer Рейтинг: Цена: 214280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines."
Автор: Wen Название: Vaccine Production and Manufacturing ISBN: 0470261943 ISBN-13(EAN): 9780470261941 Издательство: Wiley Рейтинг: Цена: 136170.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Vaccine Production and Manufacturing is a valuable reference on how to produce a vaccine, from beginning to end. It addresses all classes of vaccines from a processing, production, and regulatory viewpoint. It covers everything from fermentation, purification, and formulation to regulatory filing and facility design.
Автор: Gwyn Davies (Editor) Название: Vaccine Adjuvants: Methods and Protocols (Methods in Molecular Biology) ISBN: 1607615843 ISBN-13(EAN): 9781607615842 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The study of vaccine adjuvants has developed into an exciting area of work. In this authoritative and versatile book, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products.
Автор: Alexander von Gabain; Christoph Klade Название: Development of Novel Vaccines ISBN: 3709117046 ISBN-13(EAN): 9783709117040 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Covering the entire process of developing a vaccine-from early, basic research right up to the final product itself, and approaching the subject from a variety of perspectives, this volume will be required reading for researchers engaged in vaccine creation.
Автор: Fox Название: Vaccine Adjuvants ISBN: 1493964437 ISBN-13(EAN): 9781493964437 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into in silico design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, the analytical characterization of adjuvant formulations and adjuvant-containing vaccines, as well as the biological characterization of vaccine adjuvant activity, including in vitro and in vivo approaches, to measure innate and adaptive immune responses. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Practical and authoritative, Vaccine Adjuvants: Methods and Protocols aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better characterized.
Essential information for architects, designers, engineers, equipment suppliers, and other professionals who are working in or entering the biopharmaceutical manufacturing field
Biomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature--and it's rarely taught in architecture or design schools. This is the first book for architects and designers that fills this void. Process Architecture in Biomanufacturing Facility Design provides information on design principles of biopharmaceutical manufacturing facilities that support emerging innovative processes and technologies, use state-of-the-art equipment, are energy efficient and sustainable, and meet regulatory requirements.
Relying on their many years of hands-on design and operations experience, the authors emphasize concepts and practical approaches toward design, construction, and operation of biomanufacturing facilities, including product-process-facility relationships, closed systems and single use equipment, aseptic manufacturing considerations, design of biocontainment facility and process based laboratory, and sustainability considerations, as well as an outlook on the facility of the future.
Provides guidelines for meeting licensing and regulatory requirements for biomanufacturing facilities in the U.S.A and WHO--especially in emerging global markets in India, China, Latin America, and the Asia/Pacific regions
Focuses on innovative design and equipment, to speed construction and time to market, increase energy efficiency, and reduce footprint, construction and operational costs, as well as the financial risks associated with construction of a new facility prior to the approval of the manufactured products by regulatory agencies
Includes many diagrams that clarify the design approach
Process Architecture in Biomanufacturing Facility Design is an ideal text for professionals involved in the design of facilities for manufacturing of biopharmaceuticals and vaccines, biotechnology, and life-science industry, including architects and designers of industrial facilities, construction, equipment vendors, and mechanical engineers. It is also recommended for university instructors, advanced undergraduates, and graduate students in architecture, industrial engineering, mechanical engineering, industrial design, and industrial interior design.
Автор: Camilla Foged; Thomas Rades; Yvonne Perrie; Sarah Название: Subunit Vaccine Delivery ISBN: 1493914162 ISBN-13(EAN): 9781493914166 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccines. Part one provide a basic background with respect to immunology and general vaccine classification. In part two, it presents representative types of vaccine delivery systems individually with focus on the physicochemical properties of the systems and their significance for the immune response they stimulate. These delivery systems include aluminum adjuvants, emulsions, liposomes, bilosomes, cubosomes/hexosomes, ISCOMs, virus-like particles, polymeric nano- and microparticles, gels, implants and cell-based delivery systems. Following these chapters, part three addresses the challenges associated with vaccine delivery via specific routes of administration—in particular subcutaneous, intramuscular, oral, nasal, pulmonary, transdermal and vaginal administration. Furthermore, the specific administration routes are discussed in combination with device technologies relevant for the respective routes as well as dosage forms appropriate for the device technology. Finally, the fourth part concerns pharmaceutical analysis and quality control of subunit vaccines.
Автор: C.F.M. Hendriksen Название: Laboratory animals in vaccine production and control ISBN: 9401070881 ISBN-13(EAN): 9789401070881 Издательство: Springer Рейтинг: Цена: 95770.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: MUMPS VACCINE . . . . . . . Abnormal-toxicity test 98 7. . . . . . . . Test for residual live virus 99 7. Tests for extraneous agents 100 7. Test for Mycobacterium tuberculosis . . . . . Test for extraneous viruses 100 7. . . . . 100 XII 7 . Potency test . . . . . . . Test for abnormal toxicity 102 7. Test for extraneous agents 103 7.
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