Vaccine Adjuvants: Methods and Protocols (Methods in Molecular Biology), Gwyn Davies (Editor)

Автор: Zachariou Michael
Название: Affinity Chromatography / Methods and Protocols
ISBN: 1588296598 ISBN-13(EAN): 9781588296597
Издательство: Springer
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Цена: 13330.00 T
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Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists.  Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.

Автор: Ludewig Burkhard, Hoffmann Matthias W.
Название: Adoptive Immunotherapy / Methods and Protocols
ISBN: 1588294064 ISBN-13(EAN): 9781588294067
Издательство: Springer
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Цена: 163040.00 T
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Описание: An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy.

Автор: Smales C. Mark, James David C.
Название: Therapeutic Proteins / Methods and Protocols
ISBN: 1588293904 ISBN-13(EAN): 9781588293909
Издательство: Springer
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Цена: 186330.00 T
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Описание: World-class researchers share their innovative and proven techniques for the production of therapeutic proteins downstream of the discovery stage. The methods use a variety of sources for producing therapeutic proteins, including bacterial and yeast expression systems, and insect and mammalian cells, and then cover the purification of the resulting protein using both state-of-the-art and traditional methods, such as those sourced from plasma. Additional chapters offer methods for the characterization of therapeutic proteins throughout the production process, along with methods and strategies for viral inactivation and protein formulation. The protocols follow the successful Methods in Molecular Biologyв„ў series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Автор: Barry R. Bloom
Название: The Vaccine Book,
ISBN: 0121072584 ISBN-13(EAN): 9780121072582
Издательство: Elsevier Science
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Цена: 69710.00 T
Наличие на складе: Невозможна поставка.
Описание: Reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, and how to introduce vaccines into widespread use. This book includes topics such as: ethics; economics; diseases that could be prevented; clinical trial designs; ideas about the future of vaccines; planning vaccine trials; and more.

Автор: Fox
Название: Vaccine Adjuvants
ISBN: 1493964437 ISBN-13(EAN): 9781493964437
Издательство: Springer
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Цена: 139750.00 T
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Описание: This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into in silico design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, the analytical characterization of adjuvant formulations and adjuvant-containing vaccines, as well as the biological characterization of vaccine adjuvant activity, including in vitro and in vivo approaches, to measure innate and adaptive immune responses. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Robinson
Название: Vaccine Protocols
ISBN: 1588291405 ISBN-13(EAN): 9781588291400
Издательство: Springer
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Цена: 172350.00 T
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Описание: This extensively revised, updated, and expanded second edition of a classic laboratory manual applies new understanding of molecular mechanisms to the rational design and development of vaccines. Here the working researcher will find readily reproducible techniques for the development and production of live attenuated vaccines, and vaccines based on inactivated toxins, peptides, and polysaccharide conjugates New to this edition are cutting-edge chapters on two different viral vectors (Vaccinia and Semliki Forest), lactic acid bacteria for delivery of foreign antigens, incorporation of immunomodulators into plasmid DNA vaccines, construction of tetramer complexes to detect CMI responses, assessment of functional antibody responses, and the use of complete genome sequences for vaccine design.

There are also chapters describing more general techniques for vaccine formulation, delivery, and assessment of immune responses, and review discussions of scale-up to manufacture, vaccine quality assurance, and clinical trials.

Автор: Wen
Название: Vaccine Production and Manufacturing
ISBN: 0470261943 ISBN-13(EAN): 9780470261941
Издательство: Wiley
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Цена: 136170.00 T
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Описание: Vaccine Production and Manufacturing is a valuable reference on how to produce a vaccine, from beginning to end. It addresses all classes of vaccines from a processing, production, and regulatory viewpoint. It covers everything from fermentation, purification, and formulation to regulatory filing and facility design.

Автор: Koff
Название: Vaccine Research and Development
ISBN: 082478619X ISBN-13(EAN): 9780824786199
Издательство: Taylor&Francis
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Цена: 244990.00 T
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Описание: Reviews advances in immunization research and addresses scientific and public policy challenges for moving candidate vaccines from the laboratory to the population. This title analyzes the capacity of lipophilic components to chemically modify peptide and protein antigens and augment their immunogenicity.

Автор: Plotkin
Название: History of Vaccine Development
ISBN: 1441913386 ISBN-13(EAN): 9781441913388
Издательство: Springer
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Цена: 204970.00 T
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Описание: Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines."

Автор: Bloom, Barry R.
Название: The Vaccine Book
ISBN: 0128021748 ISBN-13(EAN): 9780128021743
Издательство: Elsevier Science
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Цена: 105540.00 T
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Описание: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. . Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk.

Автор: Carr Daniel J. J.
Название: Interferon Methods and Protocols
ISBN: 1588294188 ISBN-13(EAN): 9781588294180
Издательство: Springer
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Цена: 111790.00 T
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Описание: A compendium of methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. This book offers researchers tools not only to ascertain the functions of IFN-stimulatory gene products, but also to identify additional molecular pathways that will clarify our understanding of various biological events influenced by IFNs.