Автор: Susanne Hummel Название: Ancient DNA Typing ISBN: 3642077056 ISBN-13(EAN): 9783642077050 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This is the definitive source of information on techniques for the identification and sequencing of old DNA (pieces) and their use in biological and medical research and application. Application of aDNA techniques are useful tools for investigations reaching from evolutionary studies to law enforcement approaches.
Автор: Takashi Ohyama Название: DNA Conformation and Transcription ISBN: 1489995072 ISBN-13(EAN): 9781489995070 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Despite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differential expression of genes is enabled in a given cell type. Exploring and answering these questions constitutes one of the next frontiers in the 21st century.
We are just beginning to appreciate how Multifarious DNA structures provide additional structural and functional dimensions to chromatin organization and gene expression. DNA Conformation and Transcription is the first book that compiles the fruits of the studies that have been performed to date to solve the riddle 'written' in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code."
Автор: Goodwin Название: Forensic DNA Typing Protocols ISBN: 149393595X ISBN-13(EAN): 9781493935956 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Thisvolume presents a series of protocols and methods, some of which are not widelyused by researchers/practitioners, and will aid in the execution of differentlaboratory techniques. Forensic DNA Typing Protocols, Second Edition isarranged into a series of related chapters. Chapter 1-3 examines two differentaspects of RNA analysis for body fluid identification. Chapters 4-7 focuses onthe storage of biological materials and the extraction of DNA from hardtissues. Chapters 8-10 present methods for monitoring the quality of DNAextracts, and steps to aid in the purification of DNA. Chapters 11-16 talkabout methods on non-standard markers, such as INDELs, Y chromosome STRs, andmitochondrial DNA. Detailed procedures and data analysis for phenotypes andancestry are explored in Chapter 17-19. The last chapter (20) looks at theapplication of DNA typing to the identification of non-human material tospecies level. Written in the highly successful Methods in Molecular Biologyseries format, chapters include introductions to their respective topics,lists of the necessary materials and reagents, step-by-step, readilyreproducible laboratory protocols, and tips on troubleshooting and avoidingknown pitfalls.Practical and thorough, Forensic DNA Typing Protocols, Second Edition, isa valuable resource for forensic specialists, researchers, and anyoneinterested in the field of forensic science.
Автор: Hughes Название: Synthetic DNA ISBN: 1493963414 ISBN-13(EAN): 9781493963416 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume presents state-of-the art methods for the synthesis, design, assembly, post synthesis processing, and application of synthetic DNA to modern biotechnology.
Автор: Yonggang Ke; Pengfei Wang Название: 3D DNA Nanostructure ISBN: 1493964526 ISBN-13(EAN): 9781493964529 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This detailed volume presents a comprehensive technical overview of DNA nanotechnology with an emphasis on 3D DNA nanostructure design and applications. Coverage spans from basic design principles for DNA and RNA nanostructures to their cutting-edge applications in a variety of fields, with the book divided into basic DNA and RNA nanostructure design strategies as well as applications utilizing DNA nanostructures, including but not limited to nanomedicine, bioimaging, biosensing, nanoplasmonics, nanoelectronics, nanofabrication, crystallography, biophysics, and analytical chemistry. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and authoritative, 3D DNA Nanostructure: Methods and Protocols provides the most up-to-date tutorial style overviews and technical style protocols to benefit researchers in a wide variety of areas.
Автор: Laura Kaguni Название: DNA Replication Across Taxa,39 ISBN: 0128047356 ISBN-13(EAN): 9780128047354 Издательство: Elsevier Science Рейтинг: Цена: 123520.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
DNA Replication Across Taxa, the latest volume in The Enzymes series summarizes the most important discoveries associated with DNA replication.
Автор: Schleef Название: Minicircle and Miniplasmid DNA Vectors: The Future of Non-viral and Viral Gene Transfer ISBN: 3527324569 ISBN-13(EAN): 9783527324569 Издательство: Wiley Рейтинг: Цена: 97100.00 T Наличие на складе: Поставка под заказ. Описание: * Covers a new approach to gene therapy with a greatly improved safety profile * Complete coverage of the topic including molecular basis, production and biomedical applications * Has a wide audience including everyone who is directly or indirectly involved in the development of gene therapies .
Автор: Maria Spies Название: DNA Helicases and DNA Motor Proteins ISBN: 1489998519 ISBN-13(EAN): 9781489998514 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Integrating knowledge obtained through such approaches as single-molecule biophysics and cellular biological studies, this book offers the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors.
Автор: Rothenberg Karen H., Bush Lynn W. Название: The Drama of DNA: Narrative Genomics ISBN: 0199309353 ISBN-13(EAN): 9780199309351 Издательство: Oxford Academ Рейтинг: Цена: 55970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Through the use of dramatic narratives, The Drama of DNA brings to life the complexities raised by the application of genomic technologies to health care and diagnosis. This creative, pedagogical approach shines a unique light on the ethical, psychosocial, and policy challenges that emerge as comprehensive sequencing of the human genome transitions from research to clinical medicine.
Автор: Kum Kum Khanna; Yosef Shiloh Название: The DNA Damage Response: Implications on Cancer Formation and Treatment ISBN: 940077995X ISBN-13(EAN): 9789400779952 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Written by active investigators who have made important contributions in their respective areas, this book offers an up-to-date and comprehensive review of the latest advances in DNA damage sensing, signaling and repair.
Автор: L. Mar?a Sierra; Isabel Gaiv?o Название: Genotoxicity and DNA Repair ISBN: 1493910671 ISBN-13(EAN): 9781493910670 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields.
Автор: J?rg Tost Название: DNA Methylation Protocols ISBN: 1493974793 ISBN-13(EAN): 9781493974795 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This third edition volume expands on the previous editions by providing a comprehensive update on the available technologies required to successfully perform DNA methylation analysis. The different technologies discussed in this book analyze the global DNA methylation contents, comprehensive analyses using various NGS based methods for genome-wide DNA methylation analysis, along with precise quantification of DNA methylation levels on single CpG positions. The chapters in this book are divided into 7 parts: an introduction to the field along with tips on study design and data analysis; global DNA methylation levels; genome-wide DNA methylation analysis; highly multiplexed target regions; locus-specific DNA methylation analysis; DNA methylation analysis of specific biological samples; and hydroxymethylation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials
and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, DNA Methylation Protocols, Third Edition is a valuable resource for postdoctoral investigators and research scientists who work with different aspects of genetics, and cellular and molecular biology, as well as clinicians who are involved in diagnostics or treatment of diseases with epigenetic components.
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