Автор: Zachariou Michael Название: Affinity Chromatography / Methods and Protocols ISBN: 1588296598 ISBN-13(EAN): 9781588296597 Издательство: Springer Рейтинг: Цена: 13330.00 T Наличие на складе: Есть Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists. Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.
Автор: Didenko Vladimir V. Название: In Situ Detection of DNA Damage / Methods and Protocols ISBN: 0896039528 ISBN-13(EAN): 9780896039520 Издательство: Springer Рейтинг: Цена: 38730.00 T Наличие на складе: Есть Описание: In In Situ Detection of DNA Damage: Methods and Protocols, Vladimir Didenko and a panel of experts describe all the major in situ techniques for studying DNA damage and apoptosis, and how approaches originally designed to label apoptotic cells can be used for DNA damage analysis (and vice versa). The readily reproducible techniques presented here include all those designed to detect specific single- and double-stranded DNA breaks in tissue sections while using polymerases, ligases, nucleases, and kinases. There are also novel instrumental techniques that use ultrasound for in vivo and in situ detection of apoptotic DNA damage, and in situ applications of flow and laser-scanning cytometry for analysis of DNA strand breaks and apoptosis. State-of-the-art and highly practical, In Situ Detection of DNA Damage: Methods and Protocols presents for the first time a complete set of enzymatic methods for determining DNA breaks, and will greatly facilitate the work of all those studying the in situ detection of DNA damage and the labeling of apoptotic cells.
Автор: Kwok Pui-Yan Название: Single Nucleotide Polymorphisms / Methods and Protocols ISBN: 0896039684 ISBN-13(EAN): 9780896039681 Издательство: Springer Цена: 38730.00 T Наличие на складе: Есть Описание: Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
Автор: Dettmeyer Название: Forensic Histopathology ISBN: 3642206581 ISBN-13(EAN): 9783642206580 Издательство: Springer Рейтинг: Цена: 130390.00 T Наличие на складе: Поставка под заказ. Описание: This book, which combines the features of an atlas and a textbook, presents findings in forensic histology, immunohistochemistry, and cytology based on microscopic investigations using different stainings and different antibodies. The principal aim is to provide practitioners with detailed information and guidance on how microscopy can help to clarify the cause of sudden and unexpected death. Many of the topics will be of interest not only to forensic pathologists but also to general pathologists, whether practitioners or researchers. Examples include the pathology of drug abuse, wound age determination, adverse drug reactions, histopathology of the sudden infant death syndrome, and age determination of myocardial infarction. Both typical and unusual findings are demonstrated with the aid of numerous high-quality color illustrations, and other key literature in forensic histology and immunohistochemistry is highlighted for each topic.
Автор: Carracedo Название: Forensic DNA Typing Protocols ISBN: 1617374628 ISBN-13(EAN): 9781617374623 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A state-of-the-art collection of readily reproducible laboratory methods for DNA identity analysis, including Y chromosome haplotyping, mtDNA, and SNP typing. For forensic geneticists, there are readily reproducible methods for species identification, ancient DNA, and pharmacogenetics.
Автор: Andras Perl (Editor) Название: Autoimmunity: Methods and Protocols (Methods in Molecular Biology) ISBN: 1607617196 ISBN-13(EAN): 9781607617198 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease.
Автор: LeDoux, Joseph (Ed.) Название: Gene therapy protocols: Volume 1 preliminary entry 2071 production and in vivo applications of gene transfer vectors ISBN: 1588299031 ISBN-13(EAN): 9781588299031 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Поставка под заказ. Описание: Describes methods for the production of viral and non-viral gene transfer vectors, as well as protocols for critical applications in stem cell biology, cancer, diabetes, HIV and tissue engineering.
Автор: John M. Butler Название: Fundamentals of Forensic DNA Typing, ISBN: 0123749999 ISBN-13(EAN): 9780123749994 Издательство: Elsevier Science Рейтинг: Цена: 44910.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Explains the DNA analysis process beginning with collection of evidence at a crime scene to the statistical interpretation of the results. This book details genetic genealogy and tracing domestic pet hairs to perpetrators. It includes a glossary with over 400 terms for reference of unfamiliar terms and an acronym guide to decipher the DNA dialect.
Название: Forensic DNA applications ISBN: 1466580224 ISBN-13(EAN): 9781466580220 Издательство: Taylor&Francis Рейтинг: Цена: 148010.00 T Наличие на складе: Невозможна поставка. Описание:
Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome-based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system.
The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control.
The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains--including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany.
The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics.
The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues
in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.
Название: A Dictionary of Forensic Science ISBN: 0199594007 ISBN-13(EAN): 9780199594009 Издательство: Oxford Academ Рейтинг: Цена: 15830.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This new dictionary covers a wide range of terms used in the field of forensic science, touching on related disciplines such as chemistry, biology, and anthropology. Case examples, figures, and photographs make it the ideal reference for students and practitioners of forensic science, as well as those with an interest in forensic science.
Автор: LeDoux, Joseph (Ed.) Название: Gene therapy protocols: Vol 2 design and characterization of gene transfer vectors ISBN: 160327247X ISBN-13(EAN): 9781603272476 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The field of gene therapy has undergone remarkable advances, promising to impact human healthcare in the 21st century. This book provides methods for the processing and characterization of viral and non-viral gene transfer vectors, as well as promising approaches to design vectors for efficient, targeted and regulated gene delivery and expression.
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