Автор: Jean C Zenklusen Название: Collaborative Genomics Projects: A Comprehensive Guide ISBN: 0128021438 ISBN-13(EAN): 9780128021439 Издательство: Elsevier Science Рейтинг: Цена: 69610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: "
Collaborative Genomics Projects: A Comprehensive Guide" contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting.
This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types.
As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences. Establishes a framework for managing large-scale genomic research projects involving multiple collaboratorsDescribes lessons learned through TCGA to prepare for potential roadblocksEvaluates policy considerations that are needed to avoid pitfallsRecommends strategies to make project management more efficient
Автор: Klaassen Название: Casarett & Doull`S Toxicology: The Basic Science Of Poisons ISBN: 0071769234 ISBN-13(EAN): 9780071769235 Издательство: McGraw-Hill Рейтинг: Цена: 103250.00 T Наличие на складе: Невозможна поставка. Описание: Provides an overview of the biomedical and environmental aspects of toxicology. This book not only delivers a review of the essential components of toxicology, it also looks at the systemic responses of toxic substance available anywhere.
Автор: Holmqvist, Kenneth; Nystrom, Marcus; Andersson, Ri Название: Eye Tracking: A comprehensive guide to methods and measures ISBN: 0198738595 ISBN-13(EAN): 9780198738596 Издательство: Oxford Academ Рейтинг: Цена: 60190.00 T Наличие на складе: Поставка под заказ. Описание: For centuries private bankers owned and managed their banks, usually with unlimited liability.In the mid-19th century they faced increasing competition. This book traces the rise and decline of this original form of banking, and its revival in the late 20th century as a response to the development of a new market - the management of personal wealth
Автор: Frank A Barile Название: Principles of Toxicology Testing, Second Edition ISBN: 1842145282 ISBN-13(EAN): 9781842145289 Издательство: Taylor&Francis Рейтинг: Цена: 137810.00 T Наличие на складе: Невозможна поставка. Описание: A Love Story. Dr. David Reynolds, a young American vascular surgeon, receives an invitation to practice surgery in Saudi Arabia in the late 1970s. His only hesitation is his Jewish background, even though he changed his name and stopped practicing Judaism 22 years ago. When he travels there and meets Jamila, the vibrant nurse who will be part of his surgical team, his reservations vanish. She is a Saudi princess and her father is powerful in the Kingdom, but she and David fall deeply in love. David converts to Islam to marry Jamila. After their marriage, when Davids true background is revealed, Jamilas father feels profoundly
Автор: Murray, Lindsay Название: Toxicology Handbook ISBN: 0729542246 ISBN-13(EAN): 9780729542241 Издательство: Elsevier Science Рейтинг: Цена: 68770.00 T Наличие на складе: Поставка под заказ.
Автор: Faqi, Ali S. Название: A Comprehensive Guide to Toxicology in Nonclinical Drug Developme ISBN: 0128036206 ISBN-13(EAN): 9780128036204 Издательство: Elsevier Science Рейтинг: Цена: 193130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more.
Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings.
Автор: Byrne, John H. Название: Learning and Memory: A Comprehensive Reference ISBN: 0128051590 ISBN-13(EAN): 9780128051597 Издательство: Elsevier Science Рейтинг: Цена: 1667480.00 T Наличие на складе: Поставка под заказ. Описание:
Learning and Memory: A Comprehensive Reference, Second Edition, Four Volume Set is the authoritative resource for scientists and students interested in all facets of learning and memory. This updated edition includes chapters that reflect the state-of-the-art of research in this area. Coverage of sleep and memory has been significantly expanded, while neuromodulators in memory processing, neurogenesis and epigenetics are also covered in greater detail. New chapters have been included to reflect the massive increase in research into working memory and the educational relevance of memory research. No other reference work covers so wide a territory and in so much depth.
Название: PVP:A critical review of the kinetics and toxicology of Polyvinelpyrrolidone ISBN: 0873712889 ISBN-13(EAN): 9780873712880 Издательство: Taylor&Francis Рейтинг: Цена: 433840.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this book, the authors provide information on the absorption, distribution, storage, and excretion of polyvinylpyrrolidone (PVP) and in its toxicological evaluation, discussing the pharmacokinetics of PVP over a wide range of molecular weights.
Автор: Klaassen Название: Casarett & Doull`s Toxicology.6ed ISBN: 0071347216 ISBN-13(EAN): 9780071347211 Издательство: McGraw-Hill Цена: 69770.00 T Наличие на складе: Невозможна поставка. Описание: This text aims to present concepts in logical progression from general principles to specific topics. In addition to new chapters and interior design, this edition includes recent advances in molecular biology and pharmacogenetics and thoughly revamped clinical chapters.
Автор: Klaassen Название: Casarett & Doull`S Toxicology: The Basic Science Of Poisons: Ise ISBN: 0071124535 ISBN-13(EAN): 9780071124539 Издательство: McGraw-Hill Цена: 25910.00 T Наличие на складе: Поставка под заказ. Описание: Equips you with the treatment of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline. This edition includes coverage of: the advances in molecular biology and pharmacogenetics; risk assessment; and, online references.
Автор: Daniel Ladant Название: The Comprehensive Sourcebook of Bacterial Protein Toxins ISBN: 0128001887 ISBN-13(EAN): 9780128001882 Издательство: Elsevier Science Рейтинг: Цена: 213350.00 T Наличие на складе: Невозможна поставка. Описание:
The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content.
Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them
Focused chapters on toxin applications and common properties or general features of toxins
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