Enzymology and Molecular Biology of Carbonyl Metabolism 4, Henry Weiner; David W. Crabb; T. Geoffrey Flynn

Автор: Bernard Testa
Название: Hydrolysis in Drug and Prodrug Metabolism: Chemistry, Biochemistry, and Enzymology
ISBN: 390639025X ISBN-13(EAN): 9783906390253
Издательство: Wiley
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Описание: In this volume, Professor Bernard Testa and Dr Joachim Mayer discuss the molecular and biochemical aspects of metabolic reactions of hydrolysis and hydration. While an encyclopaedic treatment is avoided, the covered topics include biochemicproperties of the enzymes/isozymes, drug-enzyme interactions, the various chemical reactions catalyzed by the enzyme(s), reaction mechanisms and catalytic cycles, regio- and stereoselectivities, structure-metabolism relationships, molecular aspects of toxication and detoxication, as well as enzyme inhibition. The classification of matters is based mainly on the types of target groups and compounds being transformed, with carefully selected examples illustrating the reactions under discussion. Such a treatment has heuristic value since it renders the reader capable of educated guesses on the metabolism of other or novel drugs.

Автор: Henry Weiner; Ronald Lindahl; David W. Crabb; T. G
Название: Enzymology and Molecular Biology of Carbonyl Metabolism 6
ISBN: 1461376920 ISBN-13(EAN): 9781461376927
Издательство: Springer
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Описание: Proceedings of the 8th International Workshop held in Deadwood, South Dakota, June 29-July 3, 1996

Автор: Spies, Maria
Название: Methods in Enzymology
ISBN: 012809267X ISBN-13(EAN): 9780128092675
Издательство: Elsevier Science
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Описание: Single-Molecule Enzymology, Part A, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in single-molecule enzymology, and includes sections on such topics as force-based and hybrid approaches, fluorescence, high-throughput sm enzymology, nanopores, and tethered particle motion.