Автор: Schleef Название: Minicircle and Miniplasmid DNA Vectors: The Future of Non-viral and Viral Gene Transfer ISBN: 3527324569 ISBN-13(EAN): 9783527324569 Издательство: Wiley Рейтинг: Цена: 97100.00 T Наличие на складе: Поставка под заказ. Описание: * Covers a new approach to gene therapy with a greatly improved safety profile * Complete coverage of the topic including molecular basis, production and biomedical applications * Has a wide audience including everyone who is directly or indirectly involved in the development of gene therapies .
Автор: Merten Название: Viral Vectors for Gene Therapy ISBN: 161779094X ISBN-13(EAN): 9781617790942 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The huge potential for gene therapy to cure a wide range of diseases has led to high expectations and a great increase in research efforts in this area, particularly in the study of delivery via viral vectors, widely considered to be more efficient than DNA transfection. In Viral Vectors for Gene Therapy: Methods and Protocols, experts in the field present a collection of their knowledge and experience featuring methodologies that involve virus production, transferring protocols, and evaluating the efficacy of gene products. While thoroughly covering the most popular viral vector systems of adenovirus, retrovirus, and adeno-associated virus, this detailed volume also explores less common viral vector systems such as baculovirus, herpes virus, and measles virus, the growing interest in which is creating a considerable demand for large scale manufacturing and purification procedures. Written in the highly successful Methods in Molecular Biology™ series format, many chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and vital tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Viral Vectors for Gene Therapy: Methods and Protocols provides basic principles accessible to scientists from a wide variety of backgrounds for the development of gene therapy viral products that are safe and effective.
Автор: LeDoux, Joseph (Ed.) Название: Gene therapy protocols: Volume 1 preliminary entry 2071 production and in vivo applications of gene transfer vectors ISBN: 1588299031 ISBN-13(EAN): 9781588299031 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Поставка под заказ. Описание: Describes methods for the production of viral and non-viral gene transfer vectors, as well as protocols for critical applications in stem cell biology, cancer, diabetes, HIV and tissue engineering.
Автор: LeDoux, Joseph (Ed.) Название: Gene therapy protocols: Vol 2 design and characterization of gene transfer vectors ISBN: 160327247X ISBN-13(EAN): 9781603272476 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The field of gene therapy has undergone remarkable advances, promising to impact human healthcare in the 21st century. This book provides methods for the processing and characterization of viral and non-viral gene transfer vectors, as well as promising approaches to design vectors for efficient, targeted and regulated gene delivery and expression.
Автор: Federico Название: Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools ISBN: 1493937510 ISBN-13(EAN): 9781493937516 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume provides current methods and protocols for geneand protein delivery based on both lentivirus-generated and spontaneouslyreleased nanovesicles. Lentiviral Vectors and Exosomes as Gene andProtein Delivery Tools guides readers through methods on macromoleculedelivery and chapters describe the LV-based protocols of gene engineering. Written in thehighly successful Methods in Molecular Biology series format, chaptersinclude introductions to their respective topics, lists of the necessarymaterials and reagents, step-by-step, readily reproducible laboratoryprotocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Lentiviral Vectors andExosomes as Gene and Protein Delivery Tools aims to ensure successfulresults in the further study of this vital field.
Автор: Patrick Arbuthnot Название: Gene Therapy for Viral Infections ISBN: 0124105181 ISBN-13(EAN): 9780124105188 Издательство: Elsevier Science Рейтинг: Цена: 116780.00 T Наличие на складе: Невозможна поставка. Описание:
Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options.
Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors.
Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology.
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