Bayesian Designs for Phase I–II Clinical Trials, Yuan

Автор: Wilkinson, Ian B.
Название: Oxford handbook of clinical medicine. 10 ed
ISBN: 0199689903 ISBN-13(EAN): 9780199689903
Издательство: Oxford Academ
Рейтинг:
Цена: 35890.00 T
Наличие на складе: Невозможна поставка.
Описание: The Oxford Handbook of Clinical Medicine, a peerless classic in the field, returns for a tenth edition. Thoroughly updated in line with current guidelines, this pocket-friendly book continues to be a truly indispensable companion for the practice of modern medicine.

Автор: Berry, Donald A. Berry, Scott M. Carlin, Bradley P
Название: Bayesian adaptive methods for clinical trials
ISBN: 1439825483 ISBN-13(EAN): 9781439825488
Издательство: Taylor&Francis
Рейтинг:
Цена: 112290.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Explores the growing role of Bayesian thinking in the rapidly changing world of clinical trial analysis. This book summarizes the state of clinical trial design and analysis and introduces the main ideas and potential benefits of a Bayesian alternative.

Автор: Kerry B. Barker, Sandeep M. Menon, Ralph B. D`Agostino, Siyan Xu, Bo Jin
Название: Biosimilar Clinical Development: Scientific Considerations and New Methodologies
ISBN: 1482231697 ISBN-13(EAN): 9781482231694
Издательство: Taylor&Francis
Рейтинг:
Цена: 132710.00 T
Наличие на складе: Нет в наличии.
Описание: Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in clinical development, this book discusses various potential drug development strategies, the design and analysis of pharmacokinetics (PK) studies, and the design and analysis of efficacy studies.

Автор: Balakrishnan
Название: Methods and Applications of Statistics in Clinical Trials: Volume 1 - Concepts, Principles, Trials, and Designs
ISBN: 111830473X ISBN-13(EAN): 9781118304730
Издательство: Wiley
Рейтинг:
Цена: 190030.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive book features both new and established material on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data.

Автор: Wassmer
Название: Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
ISBN: 3319325604 ISBN-13(EAN): 9783319325606
Издательство: Springer
Рейтинг:
Цена: 121110.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven change of relevant aspects of the study design at interim stages. This includes, for example, a sample-size reassessment, a treatment-arm selection or a selection of a pre-specified sub-population. Essentially, this adaptive methodology was introduced in the 1990s. Since then, it has become popular and the object of intense discussion and still represents a rapidly growing field of statistical research. This book describes adaptive design methodology at an elementary level, while also considering designing and planning issues as well as methods for analyzing an adaptively planned trial. This includes estimation methods and methods for the determination of an overall p-value. Part I of the book provides the group sequential methods that are necessary for understanding and applying the adaptive design methodology supplied in Parts II and III of the book. The book contains many examples that illustrate use of the methods for practical application. The book is primarily written for applied statisticians from academia and industry who are interested in confirmatory adaptive designs. It is assumed that readers are familiar with the basic principles of descriptive statistics, parameter estimation and statistical testing. This book will also be suitable for an advanced statistical course for applied statisticians or clinicians with a sound statistical background.

Автор: Glick, Henry A.; Doshi, Jalpa A.; Sonnad, Seema S.
Название: Economic Evaluation in Clinical Trials
ISBN: 0199685029 ISBN-13(EAN): 9780199685028
Издательство: Oxford Academ
Рейтинг:
Цена: 68640.00 T
Наличие на складе: Поставка под заказ.
Описание: A a practical guide to the techniques and issues involved in conducting economic evaluation in ongoing clinical trials, supported with detailed advice on the design and analysis of studies including analysis of cost effectiveness and methodological integrity.

Автор: Takashi Daimon; Akihiro Hirakawa; Shigeyuki Matsui
Название: An Introduction to Dose-Finding Methods in Early Phase Clinical Trials
ISBN: 4431555846 ISBN-13(EAN): 9784431555841
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Included are rule-based and model-based designs, such as 3 + 3 designs, accelerated titration designs, toxicity probability interval designs, continual reassessment method and related designs, and escalation overdose control designs.

Автор: Cleophas
Название: Modern Bayesian Statistics in Clinical Research
ISBN: 3319927469 ISBN-13(EAN): 9783319927466
Издательство: Springer
Рейтинг:
Цена: 60550.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The current textbook has been written as a help to medical / health professionals and students for the study of modern Bayesian statistics, where posterior and prior odds have been replaced with posterior and prior likelihood distributions.

Автор: Ettore Marubini
Название: Analysing Survival Data from Clinical Trials and Observational Studies
ISBN: 0470093412 ISBN-13(EAN): 9780470093412
Издательство: Wiley
Рейтинг:
Цена: 81260.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an up--to--date, comprehensive, clinically oriented account of the molecular biology, pathogenesis, clinical features, diagnosis and management of human bacterial diseases, as well as their control and prevention.

Автор: Fayers, Peter; Hays, Ron
Название: Assessing Quality of Life in Clinical Trials
ISBN: 0198527691 ISBN-13(EAN): 9780198527695
Издательство: Oxford Academ
Рейтинг:
Цена: 147840.00 T
Наличие на складе: Невозможна поставка.
Описание: Researchers in all clinical fields are fully aware of the importance of Quality of Life measurements in judging the efficacy of a given treatment. Psychological criteria play an important role in this evaluation. Assessing Quality of Life in Clinical Trials explores the current state of the art and illustrates the benefits and potential of health related quality of life assessment in clinical trials. It cover a wide range of analytical issues, emphasizing new and innovative approaches that are of practical and clinical importance. The book will have widespread appeal to clinical trialists and researchers from a wide range of specialties.