Bayesian adaptive methods for clinical trials, Berry, Donald A. Berry, Scott M. Carlin, Bradley P
Автор: Thompson John Название: Bayesian Analysis with Stata ISBN: 1597181412 ISBN-13(EAN): 9781597181419 Издательство: Taylor&Francis Рейтинг: Цена: 57150.00 T Наличие на складе: Невозможна поставка. Описание:
Bayesian Analysis with Stata is written for anyone interested in applying Bayesian methods to real data easily. The book shows how modern analyses based on Markov chain Monte Carlo (MCMC) methods are implemented in Stata both directly and by passing Stata datasets to OpenBUGS or WinBUGS for computation, allowing Stata's data management and graphing capability to be used with OpenBUGS/WinBUGS speed and reliability.
The book emphasizes practical data analysis from the Bayesian perspective, and hence covers the selection of realistic priors, computational efficiency and speed, the assessment of convergence, the evaluation of models, and the presentation of the results. Every topic is illustrated in detail using real-life examples, mostly drawn from medical research.
The book takes great care in introducing concepts and coding tools incrementally so that there are no steep patches or discontinuities in the learning curve. The book's content helps the user see exactly what computations are done for simple standard models and shows the user how those computations are implemented. Understanding these concepts is important for users because Bayesian analysis lends itself to custom or very complex models, and users must be able to code these themselves.
Автор: David J. Spiegelhalter Название: Bayesian Approaches to Clinical Trials and Health-Care Evaluation ISBN: 0471499757 ISBN-13(EAN): 9780471499756 Издательство: Wiley Рейтинг: Цена: 70700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council`s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries.
Автор: Wassmer Название: Group Sequential and Confirmatory Adaptive Designs in Clinical Trials ISBN: 3319325604 ISBN-13(EAN): 9783319325606 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven change of relevant aspects of the study design at interim stages. This includes, for example, a sample-size reassessment, a treatment-arm selection or a selection of a pre-specified sub-population. Essentially, this adaptive methodology was introduced in the 1990s. Since then, it has become popular and the object of intense discussion and still represents a rapidly growing field of statistical research. This book describes adaptive design methodology at an elementary level, while also considering designing and planning issues as well as methods for analyzing an adaptively planned trial. This includes estimation methods and methods for the determination of an overall p-value. Part I of the book provides the group sequential methods that are necessary for understanding and applying the adaptive design methodology supplied in Parts II and III of the book. The book contains many examples that illustrate use of the methods for practical application. The book is primarily written for applied statisticians from academia and industry who are interested in confirmatory adaptive designs. It is assumed that readers are familiar with the basic principles of descriptive statistics, parameter estimation and statistical testing. This book will also be suitable for an advanced statistical course for applied statisticians or clinicians with a sound statistical background.
Автор: David G. T. Denison Название: Bayesian Methods for Nonlinear Classification and Regression ISBN: 0471490369 ISBN-13(EAN): 9780471490364 Издательство: Wiley Рейтинг: Цена: 137230.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Regression analysis models the relationship between a set of responses and another variable: for example, to estimate the true position of a line through a number of observed points. Unfortunately, data rarely conforms to simple curves and straight lines - parametric models - and this text examines more complex - or nonparametric - models.
Автор: Peter D. Hoff Название: A First Course in Bayesian Statistical Methods ISBN: 0387922997 ISBN-13(EAN): 9780387922997 Издательство: Springer Рейтинг: Цена: 60550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A self-contained introduction to probability, exchangeability and Bayes` rule provides a theoretical understanding of the applied material. The development of Monte Carlo and Markov chain Monte Carlo methods in the context of data analysis examples provides motivation for these computational methods.
Автор: Chen Ming-Hui, Shao Qi-Man, Ibrahim Joseph G. Название: Monte Carlo Methods in Bayesian Computation ISBN: 0387989358 ISBN-13(EAN): 9780387989358 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines advanced Bayesian computational methods. It presents methods for sampling from posterior distributions and discusses how to compute posterior quantities of interest using Markov chain Monte Carlo (MCMC) samples. This book examines each of these issues in detail and heavily focuses on computing various posterior quantities of interest from a given MCMC sample. Several topics are addressed, including techniques for MCMC sampling, Monte Carlo methods for estimation of posterior quantities, improving simulation accuracy, marginal posterior density estimation, estimation of normalizing constants, constrained parameter problems, highest posterior density interval calculations, computation of posterior modes, and posterior computations for proportional hazards models and Dirichlet process models. The authors also discuss computions involving model comparisons, including both nested and non-nested models, marginal likelihood methods, ratios of normalizing constants, Bayes factors, the Savage-Dickey density ratio, Stochastic Search Variable Selection, Bayesian Model Averaging, the reverse jump algorithm, and model adequacy using predictive and latent residual approaches.The book presents an equal mixture of theory and applications involving real data. The book is intended as a graduate textbook or a reference book for a one semester course at the advanced masters or Ph.D. level. It would also serve as a useful reference book for applied or theoretical researchers as well as practitioners.Ming-Hui Chen is Associate Professor of Mathematical Sciences at Worcester Polytechnic Institute, Qu-Man Shao is Assistant Professor of Mathematics at the University of Oregon. Joseph G. Ibrahim is Associate Professor of Biostatistics at the Harvard School of Public Health and Dana-Farber Cancer Institute.
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