Автор: Reeve Название: Mitochondrial Dysfunction in Neurodegenerative Disorders ISBN: 3319286358 ISBN-13(EAN): 9783319286358 Издательство: Springer Рейтинг: Цена: 125770.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This second edition brings together up-to-date contributionsfrom leaders in the field internationally on the various ways in whichmitochondrial dysfunction contributes to the pathogenesis of neurodegenerativediseases, including Parkinson’s disease, Alzheimer’s disease and multiplesclerosis. The reader is guided through the basic functions of mitochondria andthe mechanisms that lead to their dysfunction, and on to the consequences ofthis dysfunction for neuronal function before finishing with the modelling ofthese disorders and discussion of new potential therapeutic targets. Additional chapters have been added to the book to reflectadvances in the field and there are many new contributors and topics, includinghow mitochondria are degraded and the interaction of the mitochondria withpathologically relevant proteins. Mitochondrial Dysfunction in Neurodegenerative Disordersprovides an accessible, authoritative guide to this important area forneurologists; research and clinical neuroscientists; neuropathologists; andresidents with an interest in clinical research.
Автор: Sala, Carlo Название: Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and ISBN: 0128001097 ISBN-13(EAN): 9780128001097 Издательство: Elsevier Science Рейтинг: Цена: 104410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings.
In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders.
Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field.
The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms.
Автор: Lynne C. Weaver Название: Autonomic Dysfunction After Spinal Cord Injury,152 ISBN: 0444519254 ISBN-13(EAN): 9780444519252 Издательство: Elsevier Science Рейтинг: Цена: 224570.00 T Наличие на складе: Поставка под заказ. Описание: Intended for those who are involved in research and treatment of spinal cord injury, this book contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions.
Автор: H. M. van Praag Название: Stress, the Brain and Depression ISBN: 052162147X ISBN-13(EAN): 9780521621472 Издательство: Cambridge Academ Рейтинг: Цена: 156290.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Can traumatic life events cause depression? In this book, the authors structure their examination around three major themes: the pathophysiological role of stress in depression; whether or not a subtype of depression exists that is particularly stress-inducible; and, finally, how best to diagnose and treat depression in relation to its biological underpinnings.
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