Protein Folding and Misfolding, Heinz Fabian; Dieter Naumann
Автор: Uversky Vladimir N., Fink Anthony Название: Protein Misfolding, Aggregation and Conformational Diseases / Part B: Molecular Mechanisms of Conformational Diseases ISBN: 038736529X ISBN-13(EAN): 9780387365299 Издательство: Springer Рейтинг: Цена: 243800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The second volume continues to fill the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.
Автор: Vladimir N. Uversky; Anthony Fink Название: Protein Misfolding, Aggregation and Conformational Diseases ISBN: 1441938516 ISBN-13(EAN): 9781441938510 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.
This book reviews current research on the important processes involved in neurodegenerative diseases (e.g. Alzheimer's disease) and the peptides and proteins involved in the amyloidogenic processes. It covers the design and developments of anti-amyloid inhibitors, and gives readers a fundamental understanding of the underlying oligomerization and aggregation processes of these diseases from both computational and experimental points of view.
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