Protein Misfolding, Aggregation and Conformational Diseases, Vladimir N. Uversky; Anthony Fink

Название: Conformational proteomics of macromolecular architecture: approaching the structure of large molecular assemblies and their mechanisms of action (with cd-rom)
ISBN: 9812386149 ISBN-13(EAN): 9789812386144
Издательство: World Scientific Publishing
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Цена: 90810.00 T
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Описание: Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which "activity" can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be feasible in a large construct.

The biological implications of such adaptation will be explored as it applies to the static quasisymmetry situations, as well as to the dynamics of structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this work presents knowledge in the various fields of structural proteomics of very large molecular assemblies, with focus on their mechanisms of action.

Автор: David Neuhaus
Название: The Nuclear Overhauser Effect in Structural and Conformational Analysis, 2nd Edition
ISBN: 0471246751 ISBN-13(EAN): 9780471246756
Издательство: Wiley
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Цена: 255500.00 T
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Описание: The Nuclear Overhauser Effect (NOE) is an important branch of NMR spectroscopy concerned with structural and conformational problems.