Synaptic Plasticity and the Mechanism of Alzheimer`s Disease, Dennis J. Selkoe; Antoine Triller
Автор: Jacques Fantini Название: Brain Lipids in Synaptic Function and Neurological Disease ISBN: 0128001119 ISBN-13(EAN): 9780128001110 Издательство: Elsevier Science Рейтинг: Цена: 104410.00 T Наличие на складе: Невозможна поставка. Описание:
Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders.
Written to provide a "hands-on" approach for readers
Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings
Step-by-step guide to memorize and draw lipid structures
Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique
Автор: Michael R. Kreutz; Carlo Sala Название: Synaptic Plasticity ISBN: 3709117321 ISBN-13(EAN): 9783709117323 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book introduces current concepts of molecular mechanisms in synaptic plasticity, and offers a comprehensive overview of cutting-edge technology used to investigate the molecular dynamics of the synapses. Coverage includes clinical and applied aspects.
Автор: Trussell Название: Synaptic Mechanisms in the Auditory System ISBN: 1461429587 ISBN-13(EAN): 9781461429586 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Here is a basic reference for students, clinicians and researchers on how synapses in the auditory system function to encode acoustic signals. The volume brings together classical cell physiology, modern tools for analysis and the problems of auditory coding.
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