The Nuclear Overhauser Effect in Structural and Conformational Analysis, 2nd Edition, David Neuhaus

Название: Conformational proteomics of macromolecular architecture: approaching the structure of large molecular assemblies and their mechanisms of action (with cd-rom)
ISBN: 9812386149 ISBN-13(EAN): 9789812386144
Издательство: World Scientific Publishing
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Цена: 90810.00 T
Наличие на складе: Поставка под заказ.
Описание: Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which "activity" can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be feasible in a large construct.

The biological implications of such adaptation will be explored as it applies to the static quasisymmetry situations, as well as to the dynamics of structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this work presents knowledge in the various fields of structural proteomics of very large molecular assemblies, with focus on their mechanisms of action.

Автор: Uversky Vladimir N., Fink Anthony
Название: Protein Misfolding, Aggregation and Conformational Diseases / Part B: Molecular Mechanisms of Conformational Diseases
ISBN: 038736529X ISBN-13(EAN): 9780387365299
Издательство: Springer
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Цена: 243800.00 T
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Описание: The second volume continues to fill the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.

Автор: Vladimir N. Uversky; Anthony Fink
Название: Protein Misfolding, Aggregation and Conformational Diseases
ISBN: 1441938516 ISBN-13(EAN): 9781441938510
Издательство: Springer
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Цена: 191550.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.