Tumor Biomarker Discovery, Michael A. Tainsky (Ed.)

Автор: A. Mark Davies; Murali Sundaram; Steven L.J. James
Название: Imaging bone tumors and tumor-like lesions
ISBN: 3540779825 ISBN-13(EAN): 9783540779827
Издательство: Springer
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Цена: 269260.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A comprehensive textbook that provides a description of the imaging techniques and findings in patients with benign and malignant bone tumors. It discusses the techniques and procedures employed for imaging bone tumors. It reviews the role of these imaging techniques in diagnosis, surgical staging, biopsy, and assessment of response to therapy.

Автор: Dakubo
Название: Cancer Biomarkers in Body Fluids
ISBN: 3319015796 ISBN-13(EAN): 9783319015798
Издательство: Springer
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Цена: 167700.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well.This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.??

Автор: W. I. Wei
Название: Tumors of the Nose, Sinuses and Nasopharynx
ISBN: 3131471913 ISBN-13(EAN): 9783131471918
Издательство: Thieme Verlagsgruppe
Цена: 115610.00 T
Наличие на складе: Нет в наличии.
Описание: "This is a well-written, excellently referenced text that will truly be the leading text in its field. It will be an essential text for every skull base surgeon to have on his or her bookshelf to use as a reference and to read before tackling the more uncommon pathologies that exist in this area." -- Neurosurgery Covering tumors of the nose, sinuses, and nasopharynx for the first time in a single volume, this book is essential for all specialists. It incorporates the newest techniques for evaluation and treatment, including endoscopic approaches to the skull base, and offers a wealth of evidence-based data and analysis. For all members of the multidisciplinary health care teams who manage these complex cases, this book makes a major contribution to the field. Special Features: Written by three international authorities who have published and lectured widely and conducted landmark studies in this area Covers the full range of benign and malignant nose and sinus tumors, as well as the specific nasopharyngeal tumors that are more common to certain geographic regions (Far East) and ethnic groups (Chinese origin) Content is based on one of the largest single institutional studies ever undertaken, plus an extensive review of the international literature Encompasses every aspect of the field, from etiology, clinical features, histology, imaging studies, and diagnosis to natural history, treatment options, outcomes, and management of residual or recurrent disease Includes up-to-date contributions from experts on chemoradiation and head and neck imaging With the goal of centralizing data and long-term follow-up, this comprehensive guide is invaluable for all otolaryngologists, head and neck surgeons, oncologists, neurosurgeons, and maxillofacial and plastic surgeons who treat patients with challenging sinonasal, skull base, and nasopharyngeal neoplasms. Thieme eOtolaryngology is the premier online resource for otolaryngology-head and neck surgery. For a free trial, go to: thieme.com/eototrial

Автор: Haleem J. Issaq
Название: Proteomic and Metabolomic Approaches to Biomarker Discovery,
ISBN: 0123944465 ISBN-13(EAN): 9780123944467
Издательство: Elsevier Science
Цена: 115940.00 T
Наличие на складе: Невозможна поставка.
Описание: Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. . Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research.

Автор: Fletcher C.
Название: Diagnostic Histopathology of Tumors: 2 Volume Set, 4th Edition
ISBN: 1437715346 ISBN-13(EAN): 9781437715347
Издательство: Elsevier Science
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Цена: 363520.00 T
Наличие на складе: Невозможна поставка.
Описание: Helps you diagnose tumors with confidence. This title provides advanced, expert guidance you need to evaluate and interpret even the most challenging histopathology specimens more quickly and accurately.

Автор: Gabriel D. Dakubo
Название: Cancer Biomarkers in Body Fluids
ISBN: 3319483595 ISBN-13(EAN): 9783319483597
Издательство: Springer
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Цена: 214280.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.

Автор: Harndan
Название: Cancer Biomarkers. 2007
ISBN: 0471745162 ISBN-13(EAN): 9780471745167
Издательство: Wiley
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Цена: 142510.00 T
Наличие на складе: Поставка под заказ.
Описание: Tools, techniques, and progress in cancer biomarkers discovery The completion of a number of gene sequencing projects, recent advances in genomic and proteomic technologies, and the availability of powerful bioinformatics tools have led to promising new avenues and approaches in the search for cancer biomarkers.

Автор: Charles L. Edelstein
Название: Biomarkers of Kidney Disease,
ISBN: 0123756723 ISBN-13(EAN): 9780123756725
Издательство: Elsevier Science
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Цена: 83470.00 T
Наличие на складе: Невозможна поставка.
Описание:

A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier or more effective treatments for kidney diseases.

Biomarkers of Kidney Disease reviews the basic and clinical research on biomarkers of the common kidney diseases including acute kidney injury, chronic kidney disease, renal cancer, diabetic nephropathy, glomerular disease and preeclampsia. The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. The latest techniques for biomarker detection like metabolomics and proteomics is covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation and preeclampsia.

* Presents a comprehensive, translational source for all aspects of renal biomarkers in one reference work * Experts in renal disease biomarkers (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism) to new therapeutic approaches