New and Emerging Proteomic Techniques, Nedelkov Dobrin, Nelson Randall W.

Автор: Haleem J. Issaq
Название: Proteomic and Metabolomic Approaches to Biomarker Discovery,
ISBN: 0123944465 ISBN-13(EAN): 9780123944467
Издательство: Elsevier Science
Цена: 115940.00 T
Наличие на складе: Невозможна поставка.
Описание: Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. . Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research.

Автор: Pawel Ciborowski
Название: Proteomic Profiling and Analytical Chemistry
ISBN: 0444636889 ISBN-13(EAN): 9780444636881
Издательство: Elsevier Science
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Цена: 116780.00 T
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Описание:

"Proteomic Profiling and Analytical Chemistry: The Crossroads, Second Edition" helps scientists without a strong background in analytical chemistry to understand principles of the multistep proteomic experiment necessary for its successful completion. It also helps researchers who do have an analytical chemistry background to break into the proteomics field. Highlighting points of junction between proteomics and analytical chemistry, this resource links experimental design with analytical measurements, data analysis, and quality control. This targeted point of view will help both biologists and chemists to better understand all components of a complex proteomic study.

The book provides detailed coverage of experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more. The key feature of this book is a direct link between multistep proteomic strategy and quality control routinely applied in analytical chemistry. This second edition features a new chapter on SWATH-MS, substantial updates to all chapters, including proteomic database search and analytical quantification, expanded discussion of post-hoc statistical tests, and additional content on validation in proteomics.
Covers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measureIncludes practical examples illustrating the importance of problems in quantitation and validation of biomarkersHelps in designing and executing proteomic experiments with sound analytics

Автор: Gary B. Smejkal and Alexander Lazarev
Название: Separation Methods In Proteomics
ISBN: 0824726995 ISBN-13(EAN): 9780824726997
Издательство: Taylor&Francis
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Цена: 224570.00 T
Наличие на складе: Нет в наличии.
Описание: Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. "Separation Methods in Proteomics" provides a comprehensive examination of all major separation techniques for proteomics research. Written as a compilation of hands-on methods exemplified by the work of several recognized leaders in the field, this book may serve as a guide for selection of the optimal separation strategies to solve particular biological problems.

Recent progress in the development of robust analytical techniques and instrumentation has created the need for good quality biological samples that are subject to analysis.Emphasizing the importance of sample preparation, the book explains how proteomes can be divided into smaller, less complicated 'subproteomes' for individual analysis. It also highlights several hybrid approaches that take into account protein interactions. Including applications of the separation methods currently employed in proteomic analyses for both clinical and basic research, "Separation Methods in Proteomics" contains practical information that can enhance the current and future endeavors of scientists in proteomics, genomics, transcriptomics, biomarker discovery, and drug discovery.

Автор: Matthiesen Rune
Название: Mass Spectrometry Data Analysis in Proteomics
ISBN: 158829563X ISBN-13(EAN): 9781588295637
Издательство: Springer
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Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aims to support researchers in deciding which programs to use in various tasks related to analysis of mass spectrometry data in proteomics. This work covers chapters that give a description of the theoretical background of each topic followed by descriptions of programs and the parameters best suited for different cases.

Автор: Thongboonkerd Visith
Название: Proteomics of Human Bodyfluids / Principles, Methods, and Applications
ISBN: 1588296571 ISBN-13(EAN): 9781588296573
Издательство: Springer
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Цена: 217680.00 T
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Описание: This volume is the first collection of applications of proteomics to analyze various human body fluids. Proteomics of Human Bodyfluids consists of two parts: the first provides basic principles and strategies for proteomic analysis of human body fluids, while the second offers more details regarding methodologies and recent findings and clinical applications of each specific type of human body fluids.

Автор: Sechi Salvatore
Название: Quantitative Proteomics by Mass Spectrometry
ISBN: 1588295710 ISBN-13(EAN): 9781588295712
Издательство: Springer
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Цена: 144410.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is a compendium of cutting-edge protocols for quantitative proteomics, and presents the most significant methods used in the field today. Attention is given to state-of-the-art techniques for the characterization of the phosphoproteome and tandem MS for detection of inborn errors of metabolism.