Автор: Robinson Название: Vaccine Protocols ISBN: 1588291405 ISBN-13(EAN): 9781588291400 Издательство: Springer Рейтинг: Цена: 172350.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This extensively revised, updated, and expanded second edition of a classic laboratory manual applies new understanding of molecular mechanisms to the
rational design and development of vaccines. Here the working researcher will find readily reproducible techniques for the development and production of live attenuated vaccines, and
vaccines based on inactivated toxins, peptides, and polysaccharide conjugates
New to this edition are cutting-edge chapters on two different viral vectors (Vaccinia and Semliki Forest), lactic acid bacteria for delivery of foreign antigens, incorporation of
immunomodulators into plasmid DNA vaccines, construction of tetramer complexes to detect CMI responses, assessment of functional antibody responses, and the use of complete
genome sequences for vaccine design.
There are also chapters describing more general techniques for vaccine formulation, delivery, and assessment of immune responses,
and review discussions of scale-up to manufacture, vaccine quality assurance, and clinical trials.
Автор: Wen Название: Vaccine Production and Manufacturing ISBN: 0470261943 ISBN-13(EAN): 9780470261941 Издательство: Wiley Рейтинг: Цена: 136170.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Vaccine Production and Manufacturing is a valuable reference on how to produce a vaccine, from beginning to end. It addresses all classes of vaccines from a processing, production, and regulatory viewpoint. It covers everything from fermentation, purification, and formulation to regulatory filing and facility design.
Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines
Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications.
Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry.
The only book currently available on microneedles
Filled with tables, graphs, and black and white images (photographs, micrographs)
Authored by four experts in pharmaceutics
Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.
Автор: Plotkin Название: History of Vaccine Development ISBN: 1441913386 ISBN-13(EAN): 9781441913388 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines."
Автор: Gwyn Davies (Editor) Название: Vaccine Adjuvants: Methods and Protocols (Methods in Molecular Biology) ISBN: 1607615843 ISBN-13(EAN): 9781607615842 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The study of vaccine adjuvants has developed into an exciting area of work. In this authoritative and versatile book, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products.
Автор: Barry R. Bloom Название: The Vaccine Book, ISBN: 0121072584 ISBN-13(EAN): 9780121072582 Издательство: Elsevier Science Рейтинг: Цена: 69710.00 T Наличие на складе: Невозможна поставка. Описание: Reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, and how to introduce vaccines into widespread use. This book includes topics such as: ethics; economics; diseases that could be prevented; clinical trial designs; ideas about the future of vaccines; planning vaccine trials; and more.
Essential information for architects, designers, engineers, equipment suppliers, and other professionals who are working in or entering the biopharmaceutical manufacturing field
Biomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature--and it's rarely taught in architecture or design schools. This is the first book for architects and designers that fills this void. Process Architecture in Biomanufacturing Facility Design provides information on design principles of biopharmaceutical manufacturing facilities that support emerging innovative processes and technologies, use state-of-the-art equipment, are energy efficient and sustainable, and meet regulatory requirements.
Relying on their many years of hands-on design and operations experience, the authors emphasize concepts and practical approaches toward design, construction, and operation of biomanufacturing facilities, including product-process-facility relationships, closed systems and single use equipment, aseptic manufacturing considerations, design of biocontainment facility and process based laboratory, and sustainability considerations, as well as an outlook on the facility of the future.
Provides guidelines for meeting licensing and regulatory requirements for biomanufacturing facilities in the U.S.A and WHO--especially in emerging global markets in India, China, Latin America, and the Asia/Pacific regions
Focuses on innovative design and equipment, to speed construction and time to market, increase energy efficiency, and reduce footprint, construction and operational costs, as well as the financial risks associated with construction of a new facility prior to the approval of the manufactured products by regulatory agencies
Includes many diagrams that clarify the design approach
Process Architecture in Biomanufacturing Facility Design is an ideal text for professionals involved in the design of facilities for manufacturing of biopharmaceuticals and vaccines, biotechnology, and life-science industry, including architects and designers of industrial facilities, construction, equipment vendors, and mechanical engineers. It is also recommended for university instructors, advanced undergraduates, and graduate students in architecture, industrial engineering, mechanical engineering, industrial design, and industrial interior design.
Автор: Spriggs Название: Topics in Vaccine Adjuvant Research ISBN: 0849357195 ISBN-13(EAN): 9780849357190 Издательство: Taylor&Francis Рейтинг: Цена: 275610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Topics in Vaccine Adjuvant Research provides a concise, focused review of the immunological basis of adjuvant activity
Автор: J C Tong Название: Computer-Aided Vaccine Design, ISBN: 1907568417 ISBN-13(EAN): 9781907568411 Издательство: Elsevier Science Рейтинг: Цена: 134750.00 T Наличие на складе: Поставка под заказ. Описание: Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates.Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics.
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