Aging in Ophthalmology, Edited by Jorge L Alio MD, University Miguel Hern?

Автор: Stephen Tsang
Название: Stem Cell Biology and Regenerative Medicine in Ophthalmology
ISBN: 1489995218 ISBN-13(EAN): 9781489995216
Издательство: Springer
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Цена: 121110.00 T
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Описание: Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease. What future directions will stem cell research take? Researchers, graduate students, and fellows alike will find food for thought in this insightful guide tapping into the collective knowledge of leaders in the field. Stem Cells in Ophthalmology is part of the Stem Cells in Regenerative Medicine series dedicated to discussing current challenges and future directions in stem cell research.

Автор: Joyce Tombran-Tink; Colin J. Barnstable; Thomas W.
Название: Visual Dysfunction in Diabetes
ISBN: 1493961683 ISBN-13(EAN): 9781493961689
Издательство: Springer
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Цена: 186330.00 T
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Описание: An exciting contribution to the field, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement is designed with two overriding objectives: to help readers understand the impact of vision impairment in people living daily with diabetes rather than considering diabetic retinopathy solely as a medical problem, and to explore what we know and don't know about the ways diabetes affect the eye. With the plethora of new information being generated, there are still a series of fundamental questions that must be addressed if effective treatments for diabetic retinopathy are to be found and applied. Developed by a renowned group of authorities, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers responses and context for a range of questions, such as: do metabolic factors beyond glucose contribute to vision-threatening diabetic retinopathy? If so, how do these lead to vision impairment? Is diabetic retinopathy a response to systemic metabolic abnormalities or are there unique ocular problems related to insulin resistance? What is the relationship between the neural, vascular, and inflammatory abnormalities in diabetic retinopathy? Do they represent a pathological cascade induced sequentially or simultaneous responses to one or more metabolic perturbations? The authors note that if we do not address these types of questions, it is possible that the long process of developing new therapeutic s will target only one arm of the pathology and leave the retina open to damaging consequences of the others. State-of-the-art, comprehensive, and an invaluable addition the research and clinical literature, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers guidance and a significant step toward new scientific approaches that can lessen the devastating vision impairment associated with diabetes.

Автор: Joyce Tombran-Tink; Colin J. Barnstable
Название: Retinal Degenerations
ISBN: 1493960989 ISBN-13(EAN): 9781493960989
Издательство: Springer
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Цена: 232910.00 T
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Описание: For centuries, humans have tried to explain the complex process of vision and find effective treatments for eye diseases. Perhaps the oldest surviving record of ancient ophthalmic practices is the Babylonian code of Hammurabi that over 4000 years ago, mentioned fees for eye surgery—and penalties for unsuccessful operations that led to loss of the eye. Babylonian medicine was controlled by priests who directed the work of skilled surgeons. The earliest records of Egyptian medicine date from almost the same time. The Ebers Papyrus, dating back to more than 3500 years ago is a superbly preserved document in which a section outlines a relatively advanced system of diagnosis and treatment of various ocular pathologies. The text reveals that ancient Greek and Egyptian physicians prescribed “liver juice” for night blindness. This was obtained from roasted and crushed ox liver. We now know that their prescription contained a remarkable amount of vitamin A. It was only within the last century, however, that we have recognized the importance of vitamin A to the function of photoreceptors and visual acuity and that its deficiency can result in night blindness. Egyptian ophthalmological practices were held in high esteem in the ancient world and so were their medical institutes, called “peri-ankh,” which existed since the first dynasty. Herodotus, the fifth century BC Greek historian, comments on the specialization of the physicians: “Each physician treats just one disease.

Автор: M.A. Hayat
Название: Tumor Dormancy, Quiescence, and Senescence, Vol. 3
ISBN: 940240807X ISBN-13(EAN): 9789402408072
Издательство: Springer
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Цена: 121890.00 T
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Описание: This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia.

Автор: Guido Filogamo; Antonia Vernadakis; Fulvia Gremo;
Название: Brain Plasticity
ISBN: 0306457652 ISBN-13(EAN): 9780306457654
Издательство: Springer
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Цена: 200260.00 T
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Описание: Proceedings of the Conference on Recent Advances in Neurobiology: Plasticity and Regeneration held in St. Vincent, Italy, October 9-11 1995

Автор: Gil Atzmon, PhD
Название: Longevity Genes
ISBN: 1493955551 ISBN-13(EAN): 9781493955558
Издательство: Springer
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Цена: 113180.00 T
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Описание: The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light.

Автор: M.A. Hayat
Название: Tumor Dormancy, Quiescence, and Senescence, Volume 2
ISBN: 9402407669 ISBN-13(EAN): 9789402407662
Издательство: Springer
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Цена: 148010.00 T
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Описание: This second volume in the series exploring Tumor Dormancy, Quiescence, and Cellular Senescence offers comprehensive discussion of the role of tumor dormancy in diseases including breast cancer, melanoma, prostate cancer, liver cancer and lung cancer.

Автор: Kursad Turksen
Название: Stem Cells and Aging
ISBN: 1493963031 ISBN-13(EAN): 9781493963034
Издательство: Springer
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Цена: 111790.00 T
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Описание: This Methods in Molecular Biology (TM) book presents protocols critical for exploring the biology of stem cell aging, which is vital for understanding age-related stem cell changes at a basic biology level and at the level of their impact on regenerative medicine.

Автор: Maartje Schermer; Wim Pinxten
Название: Ethics, Health Policy and (Anti-) Aging: Mixed Blessings
ISBN: 9400799055 ISBN-13(EAN): 9789400799059
Издательство: Springer
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Цена: 158380.00 T
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Описание: This volume focuses on the ethical and philosophical issues that arise in an aging society, and the implications of these issues for healthcare and social policy. After a brief overview of biomedicine's changing approach of ageing and longevity and of the new expectations that these changes generate, various ethical, social, and policy issues that surround aging and longevity are discussed. First, the images and social meanings of aging and old age in our society are explored, including their normative dimensions and implications for policy. Next, ethical issues in the care for frail elderly are discussed, as well as notion of good care and end-of-life decisions. Finally, the ethical and social implications of emerging possibilities for anti-aging and lifespan extension are considered. The book concludes with an overview of the relevance of the issues discussed for policy making on professional, national and international levels.

Автор: Gil Atzmon, PhD
Название: Longevity Genes
ISBN: 1493924036 ISBN-13(EAN): 9781493924035
Издательство: Springer
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Цена: 130430.00 T
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Описание: The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.

Автор: M.A. Hayat
Название: Tumor Dormancy, Quiescence, and Senescence, Vol. 3
ISBN: 9401793247 ISBN-13(EAN): 9789401793247
Издательство: Springer
Рейтинг:
Цена: 139310.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia.

Автор: Guido Filogamo; Antonia Vernadakis; Fulvia Gremo;
Название: Brain Plasticity
ISBN: 147579553X ISBN-13(EAN): 9781475795530
Издательство: Springer
Рейтинг:
Цена: 191560.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Conference on Recent Advances in Neurobiology: Plasticity and Regeneration held in St. Vincent, Italy, October 9-11 1995