Basic Principles of Drug Discovery and Development, By Benjamin E. Blass, Temple University School of
Старое издание
Автор: Blass, Benjamin Название: Basic Principles Of Drug Discovery And Development ISBN: 0128172142 ISBN-13(EAN): 9780128172148 Издательство: Elsevier Science Цена: 129130 T Наличие на складе: Нет в наличии. Описание:
Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics.
Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator's fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist's early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process.
Автор: Wood Clive R Название: Antibody Drug Discovery ISBN: 1848166281 ISBN-13(EAN): 9781848166288 Издательство: World Scientific Publishing Рейтинг: Цена: 163680.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Antibody-based therapeutics are a central driver of the success of biopharmaceuticals. The discovery technology of this field is isolated to a limited number of centers of excellence in industry and academia. This title offers guidance to those evaluating and preparing to enter particular areas within the field.
Автор: Dickenson, John (Nottingham Trent University) Free Название: Molecular Pharmacology: From DNA to Drug Discovery ISBN: 0470684437 ISBN-13(EAN): 9780470684436 Издательство: Wiley Рейтинг: Цена: 87740.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Golan, David E. Название: Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy ISBN: 1496320573 ISBN-13(EAN): 9781496320575 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 59670.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Highly regarded by both students and instructors, Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 4th Edition, offers an integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development.
Автор: M.B. Sporn; Sonia B. Jakowlew Название: Transforming Growth Factor-Beta in Cancer Therapy, Volume I ISBN: 161737735X ISBN-13(EAN): 9781617377358 Издательство: Springer Рейтинг: Цена: 241310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Transforming Growth Factor- ss in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ss (TGF- ss) in cancer treatment and therapy.
Автор: Derek LeRoith Название: Insulin-like Growth Factors and Cancer ISBN: 1461429625 ISBN-13(EAN): 9781461429623 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book explores the insulin-like growth factor system and its vital role in cancer development and progression. Covers biology, epidemiology and the therapeutic potential of inhibiting receptors using newly discovered antibodies and kinase inhibitors.
Автор: Zhang Название: Drug Metabolism in Drug Design and Development - Basic Concepts and Practice ISBN: 047173313X ISBN-13(EAN): 9780471733133 Издательство: Wiley Рейтинг: Цена: 150950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Drug Metabolism in Drug Design and Development provides a practical description of what happens during the drug design and development process and focuses on issues such as: what data are needed; what experiments and analytical methods are typically employed; and how to interpret and apply data.
Автор: Blass, Benjamin Название: Basic Principles Of Drug Discovery And Development ISBN: 0128172142 ISBN-13(EAN): 9780128172148 Издательство: Elsevier Science Рейтинг: Цена: 129130.00 T Наличие на складе: Нет в наличии. Описание:
Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics.
Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator's fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist's early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process.
Автор: Ghose, Arup Viswanadhan, Vellerkad Название: Combinatorial library design and evaluation ISBN: 0367397226 ISBN-13(EAN): 9780367397227 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Поставка под заказ. Описание: This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists in academia and industry who offer coverage of basic principles, design strategies, methodologies, software tools and algorithms, and applications. It outlines the fundamentals of pharmacophore modelling and 3D Quantitative Structure-Activity Relationships (QSAR), classical QSAR, and target protein structure-based design methods.
Автор: Ghose, Arup Название: Combinatorial Library Design and Evaluation ISBN: 0824704878 ISBN-13(EAN): 9780824704872 Издательство: Taylor&Francis Рейтинг: Цена: 331760.00 T Наличие на складе: Поставка под заказ.
Автор: Erlanson Название: Fragment-based Drug Discovery - Lessons and Outlook ISBN: 352733775X ISBN-13(EAN): 9783527337750 Издательство: Wiley Рейтинг: Цена: 150950.00 T Наличие на складе: Поставка под заказ.
Автор: Urban Название: Antitargets and Drug Safety ISBN: 3527335110 ISBN-13(EAN): 9783527335114 Издательство: Wiley Рейтинг: Цена: 150950.00 T Наличие на складе: Поставка под заказ.
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