Автор: Jones, Byron Patterson, Scott D. (Pfizer Vaccines Clinical Research & Development, Collegeville, Pennsylvania, USA) Название: Bioequivalence and Statistics in Clinical Pharmacology ISBN: 0367782448 ISBN-13(EAN): 9780367782443 Издательство: Taylor&Francis Рейтинг: Цена: 48990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and interpret bioequivalence trials; explor
This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.
Автор: Omar Bagasra, Donald Gene Pace Название: Reassessing HIV Vaccine Design & Approaches: Towards a Paradigm Shift ISBN: 1622579526 ISBN-13(EAN): 9781622579525 Издательство: Nova Science Рейтинг: Цена: 267160.00 T Наличие на складе: Невозможна поставка. Описание: Provides a comprehensive text on the operative management of rotator cuff pathology, including arthroscopic and open repairs, revision surgery, tendon transfers, and reverse shoulder arthroplasty. The book also describes `tricks and tips` to help the surgeon avoid common errors that are often encountered during the procedure. Different options for each type of rotator cuff problem are presented.
Автор: Nauta Jozef Название: Statistics in Clinical and Observational Vaccine Studies ISBN: 3030376923 ISBN-13(EAN): 9783030376925 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book offers an overview of the statistical methods used in clinical and observational vaccine studies. Pursuing a practical rather than theoretical approach, it presents a range of real-world examples with SAS codes, making the application of the methods straightforward. This revised edition has been significantly expanded to reflect the current interest in this area. It opens with two introductory chapters on the immunology of vaccines to provide readers with the necessary background knowledge. It then continues with an in-depth exploration of the analysis of immunogenicity data. Discussed are, amongst others, maximum likelihood estimation for censored antibody titers, ANCOVA for antibody values, analysis of data of equivalence, and non-inferiority immunogenicity studies. Other topics covered include fitting protection curves to data from vaccine efficacy studies, and the analysis of vaccine safety data. In addition, the book features four new chapters on vaccine field studies: an introductory one, one on randomized vaccine efficacy studies, one on observational vaccine effectiveness studies, and one on the meta-analysis of vaccine efficacy studies. The book offers useful insights for statisticians and epidemiologists working in the pharmaceutical industry or at vaccines institutes, as well as graduate students interested in pharmaceutical statistics.
Автор: Lawrence Heidi Yoston Название: Vaccine Rhetorics ISBN: 0814255701 ISBN-13(EAN): 9780814255704 Издательство: Неизвестно Рейтинг: Цена: 43610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Finalist, 2021 Association for the Rhetoric of Science, Technology, and Medicine Book Award Honorable Mention, Conference on College Composition and Communication Best Book in Technical or Scientific Communication Debates over vaccination run rampant in the US--from the pages of medical journals, to news coverage about the latest outbreak, to vehement messages passed back and forth online. From the professional level to the personal one, almost everyone has an opinion on vaccinations--and often conversations around this issue pit supporters of vaccinations against "anti-vaxxers." In Vaccine Rhetorics, Heidi Yoston Lawrence turns a critical eye toward such conversations--proposing a new approach that moves us beyond divisive rhetoric and seeks to better understand the material conditions underlying the debate. Starting with a key question--If vaccines work, why are they controversial?--and using an approach she calls "material exigence," Lawrence seeks to understand the material conditions of disease and injury associated with vaccination. Examining four primary motivations--the exigency of disease at the heart of physician views, the desire for eradication from policymakers, concern over injury expressed by parents and patients in online confessionals, and questions about the unknown surrounding potential recipients of the flu vaccine, Lawrence demonstrates the complexity of vaccination skepticism and the need for more nuanced public discourse. In bringing together the voices of those who oppose, question, and support vaccines, Vaccine Rhetorics unearths the material circumstances that lead to differing viewpoints and brings important attention not just to what is said but how and why it is said--providing a useful framework for studying other controversial issues.
Автор: Sunil Thomas Название: Rickettsiales ISBN: 331946857X ISBN-13(EAN): 9783319468570 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Insect-transmitted rickettsiales diseases are significant sources of morbidity and mortality all over the world. Their incidence has been increasing in recent years in large part due to climate change and the movement of animals carrying the insect vectors. Currently there are no effective vaccines against diseases caused by members of the order Rickettsiales. Rickettsiales diseases are often misdiagnosed; this book is intended to serve as a tool for their understanding and diagnosis. Rickettsiales covers the seven main genera: Anaplasma, Ehrlichia, Midichloria, Neorickettsia, Orientia, Rickettsia and Wolbachia. Discussion of each genus includes immunology and molecular biology of host-pathogen interactions, epidemiology and diagnosis, and vaccination strategies and therapies.
Автор: M. Elizabeth Halloran; Ira M. Longini, Jr.; Claudi Название: Design and Analysis of Vaccine Studies ISBN: 1461424887 ISBN-13(EAN): 9781461424888 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.
Автор: Nauta Jozef Название: Statistics in Clinical and Observational Vaccine Studies ISBN: 3030376958 ISBN-13(EAN): 9783030376956 Издательство: Springer Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
1.The Interplay Between Microorganisms and the Immune System.- 2. Analysis of Immunogenicity Data.- 3. Vaccine Field Studies.- 4. Correlates of Protection.- 5. Analysis of Vaccine Safety Data.
A virus, pandemic, tests, cases, hospitalizations and deaths.
Something must be done...
Lockdowns, curfews, business closures, stimulus payments, furloughs, border restrictions.
The only way out...
Vaccines
The original estimate often given for producing a vaccine in record time was "12 to 18 months". Vaccines usually take at least 5 years to go through all the processes necessary to prove safety and efficacy. Yet less than a year since the viral outbreak was declared a pandemic millions had already been given the jab.
None of the vaccines have been approved, but are being used under Emergency Use Authorizations only. They are still classed as experimental, and if you are given one, you are part of the biggest vaccine trial ever run on the human race.
Despite this hasty experimental roll-out, there is a huge publicity campaign underway to encourage everyone to get vaccinated as soon as possible. The pressure is on.
The Great Vaccine Roundup of 2021
Do you have questions? Are you concerned?
Does something feel "not quite right" about all of this?
This book doesn't claim to know "the truth", nor does it suggest that the most lurid conspiracy theories are correct.
What it aims to do is help you to think through all that is going on around the world, by questioning the narrative we are being fed every day. Who is involved, what motivations might they have, why is this all happening so quickly?
This is an exercise in critical thinking, because only by doing this can we come to a rational and considered decision about what the best course of action is for our own personal and unique circumstances.
Название: Vaccine Communication in a Pandemic ISBN: 1032600381 ISBN-13(EAN): 9781032600383 Издательство: Taylor&Francis Рейтинг: Цена: 148010.00 T Наличие на складе: Нет в наличии.
Автор: Otenyo, Eric E. (professor, Department Of Politics And International Affairs, Northern Arizona University, Flagstaff, Az, Usa) Название: Covid-19 and vaccine nationalism ISBN: 0443185700 ISBN-13(EAN): 9780443185700 Издательство: Elsevier Science Рейтинг: Цена: 129130.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Казахстан, 010000 г. Астана, проспект Туран 43/5, НП2 (офис 2) ТОО "Логобук" Тел:+7 707 857-29-98 ,+7(7172) 65-23-70 www.logobook.kz
