Case Studies in Innovative Clinical Trials, Broglio, Kristine ; Yu, Binbing

Автор: Neal Michael J.
Название: Medical Pharmacology at a Glance, 9 ed
ISBN: 1119548012 ISBN-13(EAN): 9781119548010
Издательство: Wiley
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Цена: 23620.00 T
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Описание: The internationally best-selling Medical Pharmacology at a Glance is the ideal companion for all medical and healthcare students, providing a visual overview of pharmacology, and describing the basic principles of drug action, interaction, absorption, and excretion. Clear and accessible chapters organised around common diseases and conditions facilitate efficient clinical learning, and include references to drug classes and side effects, disease pathophysiology, prescribing guidelines, and more. Now in its ninth edition, this leading guide has been thoroughly updated to reflect current guidelines and drug information.

This edition features new and revised illustrations, additional pedagogical tools, and enhanced online content. Widely recognised as both the best introduction to medical pharmacology and the perfect revision tool for USMLE and pharmacology exams, this invaluable guide: Covers a wide range of drugs used to treat conditions such as hypertension, anaemias, cancer, and affective disordersExplains drug mechanisms and the principles of drug actionDiscusses practical topics including drug misuse, drug indications, and side effectsIncludes a companion website featuring online cases, flashcards, and a list of core drugs

Автор: Brown M.J. et al.
Название: Clinical Pharmacology, 12 ed. IE
ISBN: 0702073296 ISBN-13(EAN): 9780702073298
Издательство: Elsevier Science
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Цена: 38310.00 T
Наличие на складе: Поставка под заказ.
Описание:

'The very last thing a drug regulator wishes to be able to say is, like Lord Byron (1788-1824), on the publication of his poem Childe Harold's Pilgrimage, 'I awoke one morning and found myself famous.'

Автор: Katja Strohfeldt-Venables
Название: Essentials of Inorganic Chemistry: For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry.- Wiley, 2015
ISBN: 0470665580 ISBN-13(EAN): 9780470665589
Издательство: Wiley
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Цена: 49580.00 T
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Описание: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective.

Автор: Lawrence M. Friedman; Curt D. Furberg; David L. De
Название: Fundamentals of Clinical Trials
ISBN: 3319307738 ISBN-13(EAN): 9783319307732
Издательство: Springer
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Цена: 46570.00 T
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Описание: This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new material on adverse events, adherence, issues in analysis, electronic data, data sharing and international trials. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials to illustrate the fundamentals. The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan and reporting the trial results according to the pre-specified objectives. Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this text useful.

Название: Design and Analysis of Clinical Trials with Time-to-Event Endpoints
ISBN: 1420066390 ISBN-13(EAN): 9781420066395
Издательство: Taylor&Francis
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Цена: 148010.00 T
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Описание: Provides a presentation of the design, monitoring, analysis, and interpretation of clinical trials in which time-to-event is of critical interest. This book discusses the design and monitoring of Phase II and III clinical trials with time-to-event endpoints.

Автор: Fairclough
Название: Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edition
ISBN: 1420061178 ISBN-13(EAN): 9781420061178
Издательство: Taylor&Francis
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Цена: 148010.00 T
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Описание: Presents a range of solutions to analytic issues. This title reflects developments in methodology with coverage of mixture models and a dataset example. It implements examples using SAS and R code and incorporates a number of examples from real QoL clinical trials to illustrate design and analysis methods.

Автор: Kimko Hui
Название: Simulation For Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective
ISBN: 0824708628 ISBN-13(EAN): 9780824708627
Издательство: Taylor&Francis
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Цена: 183750.00 T
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Описание: Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to design clinical trials according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.

Автор: Ton J. Cleophas; Aeilko H. Zwinderman; Toine F. Cl
Название: Statistics Applied to Clinical Trials
ISBN: 1402095228 ISBN-13(EAN): 9781402095221
Издательство: Springer
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Цена: 69830.00 T
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Описание: Explains classical statistical analysis of clinical trials. This book addresses relatively novel issues, including equivalence testing, interim analysis, sequential analysis, meta-analysis, and provides a framework of the best statistical methods available for such purpose. It is suitable for investigators in the field of clinical trials.

Автор: Chang
Название: Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials
ISBN: 0815379447 ISBN-13(EAN): 9780815379447
Издательство: Taylor&Francis
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Цена: 117390.00 T
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Описание: Clinical trials require strategic thinking and innovative methods since some traditional methods are not adequate for the 21st century.To solve these problems requires good methodological skills, but also an in-depth knowledge of the practical problems we are dealing with and a strategic vision of the pig picture.

Автор: Chang, Mark (AMAG Pharmaceuticals, Inc, Lexington, Massachusetts, USA) Balser, John Roach, Jim Bliss, Robin
Название: Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials
ISBN: 1032093501 ISBN-13(EAN): 9781032093505
Издательство: Taylor&Francis
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Цена: 50010.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Clinical trials require strategic thinking and innovative methods since some traditional methods are not adequate for the 21st century.To solve these problems requires good methodological skills, but also an in-depth knowledge of the practical problems we are dealing with and a strategic vision of the pig picture.

Автор: Joseph Goldberg, Stephen Stahl
Название: Practical Psychopharmacology : Translating Findings From Evidence-Based Trials into Real-World Clinical Practice
ISBN: 1108450741 ISBN-13(EAN): 9781108450744
Издательство: Cambridge Academ
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Цена: 63360.00 T
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Описание: An accessible book for clinicians at all levels of training and experience who prescribe psychiatric medications and wish to better understand the rationale and empirical evidence base behind choosing treatments optimally tailored to the needs of individual patients.

Автор: Jie Jack Li,Douglas S. Johnson
Название: Innovative Drug Synthesis
ISBN: 1118820053 ISBN-13(EAN): 9781118820056
Издательство: Wiley
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Цена: 113990.00 T
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Описание: This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting-edge science associated with them. Following on the editors well-received prior books, this illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines.