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Principles and Practice of the Muscular Dystrophies, Narayanaswami


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Автор: Narayanaswami
Название:  Principles and Practice of the Muscular Dystrophies
ISBN: 9783031440083
Издательство: Springer
Классификация:




ISBN-10: 3031440080
Обложка/Формат: Hardback
Страницы: 348
Вес: 0.00 кг.
Дата издания: 02.03.2024
Язык: English
Основная тема: Medicine & Public Health
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The field of muscular dystrophies has expanded significantly with the discovery of the genetic defects and protein products underlying these disorders. New treatments such as antisense oligonucleotides and siRNAs and gene therapies are now in clinical application and in trials. As clinical trials increase, outcome measurement becomes very important, and more validated tools are being developed. This book provides a comprehensive review of these disorders. Clinical features, diagnostic testing including genetic testing of these disorders, the basis and utility of genetic testing, and the basis of genetic therapies are all covered in detail. This book will provide neuromuscular neurologists, general neurologists, and neuromuscular fellows with a much needed update in the field.
Дополнительное описание: An Introduction to the Muscular Dystrophies.- Dystrophinopathies.- Myotonic dystrophies.- Facioscapulohumeral Muscular Dystrophy.- Autosomal Dominant Limb-Girdle Muscular Dystrophies.- Autosomal recessive limb-girdle muscular dystrophy.- Oculopharyngeal M


Muscular Dystrophy Therapeutics

Автор: Maruyama
Название: Muscular Dystrophy Therapeutics
ISBN: 1071627740 ISBN-13(EAN): 9781071627747
Издательство: Springer
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Цена: 186330.00 T
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Описание: This detailed book presents a comprehensive collection of state-of-the-art protocols on muscular dystrophy therapeutics, covering therapeutics using antisense oligonucleotides, gene replacement, genome editing, small molecules, stem cells, and antibodies. Written by leaders in the field, the volume explores techniques that are currently in use and are starting an exciting therapeutic revolution in muscular dystrophy. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Muscular Dystrophy Therapeutics: Methods and Protocols serves as an ideal resource to inspire readers and provide tips, strategies, and advice to develop new therapeutic technologies for this group of diseases.

Muscular Dystrophy Therapeutics

Автор: Maruyama
Название: Muscular Dystrophy Therapeutics
ISBN: 1071627716 ISBN-13(EAN): 9781071627716
Издательство: Springer
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Цена: 186330.00 T
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Описание: This detailed book presents a comprehensive collection of state-of-the-art protocols on muscular dystrophy therapeutics, covering therapeutics using antisense oligonucleotides, gene replacement, genome editing, small molecules, stem cells, and antibodies. Written by leaders in the field, the volume explores techniques that are currently in use and are starting an exciting therapeutic revolution in muscular dystrophy. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Muscular Dystrophy Therapeutics: Methods and Protocols serves as an ideal resource to inspire readers and provide tips, strategies, and advice to develop new therapeutic technologies for this group of diseases.

Experimental Myopathies and Muscular Dystrophy

Автор: R. Heene
Название: Experimental Myopathies and Muscular Dystrophy
ISBN: 3642662021 ISBN-13(EAN): 9783642662027
Издательство: Springer
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Цена: 121110.00 T
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Описание: Experimental Myopathies and Muscular Dystrophy. A Study of the Formal Pathogenesis of Primary Myopathies as Exemplified in the Myopathy of 2,4-Dichlorophenoxyacetic Acid The histochemical types of muscle fibres are described and a report presented of the histological and histochemical altera- tions in skeletal muscles (tibialis anterior, gastrocnemius and soleus muscles) of rats given intraperitoneal injections of the herbicide, 2,4-dichlorophenoxyacetic acid (2,4-0). The liver and myocardium of the experimental animals were also examined. In skeletal muscle, alterations occurring acutely within 1 to 1. 5 h after injection of a single dose of 300 mg/kg 2,4-0 could be distinguished from changes which developed subacutely in the course of treatment with repeated injections of one quarter to one half of the LDSO of the substance. In both con- ditions white (type 2B/Am) muscle fibres were involved pre- dilectively. The principal histochemical effect of acute intoxi- cation observed was leakage of phosphorylase and glycogen from white muscle fibres, whereas some of the red fibres (type 2A/C ) m showed an increase in primary glycogen and phosphorylase activ- ity. These changes, which must be considered nonspecifi, were established by use of a gelatin incubation technique. They occurred as typical findings in the middle and deep areas of the anterior tibial muscle. In other muscles or different layers of the same muscle, these changes varied considerably in degree. Thus the gastrocnemius and soleus muscles displayed only minor or no alterations.

Duchenne Muscular Dystrophy

Автор: Emery Alan
Название: Duchenne Muscular Dystrophy
ISBN: 0199681481 ISBN-13(EAN): 9780199681488
Издательство: Oxford Academ
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Цена: 110880.00 T
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Описание: Fully revised and updated the new edition of Duchenne Muscular Dystrophy discusses the recent advances in the field of molecular biology for prenatal diagnosis and genetic counselling to the recent pioneering work with anti-sense oligonucleotides, and the possibility of effective RNA therapy.

Fatigue

Автор: Patricia A. Pierce; Roger M. Enoka; Simon C. Gande
Название: Fatigue
ISBN: 1489910182 ISBN-13(EAN): 9781489910189
Издательство: Springer
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Цена: 243800.00 T
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Описание: Proceedings based in part on the symposium on Neural and Neuromuscular Aspects of Muscular Fatigue held in Miami, Florida, November 10-13, 1994

The Muscular System Anatomical Chart

Автор: Acc
Название: The Muscular System Anatomical Chart
ISBN: 1587790351 ISBN-13(EAN): 9781587790355
Издательство: Lippincott Williams & Wilkins
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Цена: 18870.00 T
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Описание: Classic illustrations by Peter Bachin. Shows anterior and posterior views of the muscular system. Also illustrates right half of the diaphragm, muscles of the posterior abdominal wall, and muscles of the right foot.

Duchenne Muscular Dystrophy

Автор: Wolff, Jon
Название: Duchenne Muscular Dystrophy
ISBN: 0824723252 ISBN-13(EAN): 9780824723255
Издательство: Taylor&Francis
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Цена: 214370.00 T
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Understanding Muscular Dystrophy

Автор: Cooper Carsten
Название: Understanding Muscular Dystrophy
ISBN: 1632424185 ISBN-13(EAN): 9781632424181
Издательство: Неизвестно
Цена: 122310.00 T
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Muscular Dystrophy and Other Neuromuscular Diseases

Автор: Charash, Leon I.
Название: Muscular Dystrophy and Other Neuromuscular Diseases
ISBN: 1560240776 ISBN-13(EAN): 9781560240778
Издательство: Taylor&Francis
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Цена: 91860.00 T
Наличие на складе: Нет в наличии.

Muscular Dystrophy

Автор: Katherine M.D. Bushby; Louise V.B. Anderson
Название: Muscular Dystrophy
ISBN: 1617371408 ISBN-13(EAN): 9781617371400
Издательство: Springer
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Цена: 135090.00 T
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Описание: Some common themes can be recognized, however, including the involvement of five members of the dystrophin-associated complex (dystrophin and four sarcoglycans) in different types of MD, and the involvement of two nuclear envelope proteins in producing an Emery-Dreifuss MD phenotype.


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