Modeling and Simulation of Infectious Diseases, Zohdi
Автор: A. Holzapfel Название: Biomechanics: Trends in Modeling and Simulation ISBN: 3319414739 ISBN-13(EAN): 9783319414737 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues.The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
Автор: Emmanuel Laporte; Patrick Le Tallec Название: Numerical Methods in Sensitivity Analysis and Shape Optimization ISBN: 1461265983 ISBN-13(EAN): 9781461265986 Издательство: Springer Рейтинг: Цена: 60940.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Numerical Methods in Sensitivity Analysis and Shape Optimization will be of interest to graduate students involved in mathematical modeling and simulation, as well as engineers and researchers in applied mathematics looking for an up-to-date introduction to optimization techniques, sensitivity analysis, and optimal design.
Автор: Zohdi Название: Modeling and Simulation of Infectious Diseases ISBN: 3031180526 ISBN-13(EAN): 9783031180521 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The COVID-19 pandemic that started in 2019-2020 has led to a gigantic increase in modeling and simulation of infectious diseases. There are numerous topics associated with this epoch-changing event, such as (a) disease propagation, (b) transmission, (c) decontamination, and (d) vaccines. This is an evolving field. The targeted objective of this book is to expose researchers to key topics in this area, in a very concise manner. The topics selected for discussion have evolved with the progression of the pandemic. Beyond the introductory chapter on basic mathematics, optimization, and machine learning, the book covers four themes in modeling and simulation infectious diseases, specifically: Part 1: Macroscale disease propagation, Part 2: Microscale disease transmission and ventilation system design, Part 3: Ultraviolet viral decontamination, and Part 4: Vaccine design and immune response. It is important to emphasize that the rapid speed at which the simulations operate makes the presented computational tools easily deployable as digital twins, i.e., digital replicas of complex systems that can be inexpensively and safely optimized in a virtual setting and then used in the physical world afterward, thus reducing the costs of experiments and also accelerating development of new technologies.
Автор: HernandezVargas, Esteban Название: Modeling and Control of Infectious Diseases in the Host ISBN: 0128130520 ISBN-13(EAN): 9780128130520 Издательство: Elsevier Science Рейтинг: Цена: 93190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R.
Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases
Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases
Presents a theoretic approach to schedule drug treatments
Автор: Petr N. Vabishchevich Название: Computational Technologies: Advanced Topics ISBN: 3110359944 ISBN-13(EAN): 9783110359947 Издательство: Walter de Gruyter Цена: 61920.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book discusses questions of numerical solutions of applied problems on parallel computing systems. Nowadays, engineering and scientific computations are carried out on parallel computing systems, which provide parallel data processing on a few computing nodes. In the development of up-to-date applied software, this feature of computers must be taken into account for the maximum efficient usage of their resources. In constructing computational algorithms, we should separate relatively independent subproblems in order to solve them on a single computing node.
Автор: Morro Название: Mathematical Modelling of Continuum Physics ISBN: 3031208137 ISBN-13(EAN): 9783031208133 Издательство: Springer Рейтинг: Цена: 214280.00 T Наличие на складе: Поставка под заказ. Описание: This monograph provides a comprehensive and self-contained treatment of continuum physics, illustrating a systematic approach to the constitutive equations for wide-ranging classes of materials. Derivations of results are detailed through careful proofs, and the contents have been developed to ensure a self-contained and consistent presentation. Part I reviews the kinematics of continuous bodies and illustrates the general setting of balance laws. Essential preliminaries to continuum physics – such as reference and current configurations, transport relations, singular surfaces, objectivity, and objective time derivatives – are covered in detail. A chapter on balance equations then develops the balance laws of mass, linear momentum, angular momentum, energy, and entropy, as well as the balance laws in electromagnetism. Part II is devoted to the general requirements on constitutive models, emphasizing the application of objectivity and consistency with the second law of thermodynamics. Common models of simple materials are then reviewed, and in this framework, detailed descriptions are given of solids (thermoelastic, elastic, and dissipative) and fluids (elastic, thermoelastic, viscous, and Newtonian). A wide of variety of constitutive models are investigated in Part III, which consists of separate chapters focused on several types of non-simple materials: materials with memory, aging and higher-order grade materials, mixtures, micropolar media, and porous materials. The interaction of the electromagnetic field with deformation is also examined within electroelasticity, magnetoelasticity, and plasma theory. Hysteretic effects and phase transitions are considered in Part IV. A new approach is established by treating entropy production as a constitutive function in itself, as is the case for entropy and entropy flux. This proves to be conceptually and practically advantageous in the modelling of nonlinear phenomena, such as those occurring in hysteretic continua (e.g., plasticity, electromagnetism, and the physics of shape memory alloys). Mathematical Modelling of Continuum Physics will be an important reference for mathematicians, engineers, physicists, and other scientists interested in research or applications of continuum mechanics.
Автор: Oscar Castillo; Witold Pedrycz Название: Evolutionary Design of Intelligent Systems in Modeling, Simulation and Control ISBN: 3642045138 ISBN-13(EAN): 9783642045134 Издательство: Springer Рейтинг: Цена: 174150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Soft Computing (SC) consists of intelligent computing paradigms used to create powerful hybrid intelligent systems. This book offers new methods for evolutionary design of intelligent systems using SC and their applications in modeling, simulation and control.
Автор: Vincent Acary; Olivier Bonnefon; Bernard Brogliato Название: Nonsmooth Modeling and Simulation for Switched Circuits ISBN: 9400733852 ISBN-13(EAN): 9789400733855 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Complete with examples and simulation results, this volume explores the nonsmooth dynamical systems (NSDS) modeling approach, using piecewise-linear and multivalued models of electronic devices. Readers will find a comparison of SPICE and hybrid methods, which demonstrates the power of the NSDS approach.
Автор: Mughal Название: Real Time Modeling, Simulation and Control of Dynamical Systems ISBN: 3319339052 ISBN-13(EAN): 9783319339054 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book introduces modeling and simulation of linear time invariant systems and demonstrates how these translate to systems engineering, mechatronics engineering, and biomedical engineering. It is organized into nine chapters that follow the lectures used for a one-semester course on this topic, making it appropriate for students as well as researchers. The author discusses state space modeling derived from two modeling techniques and the analysis of the system and usage of modeling in control systems design. It also contains a unique chapter on multidisciplinary energy systems with a special focus on bioengineering systems and expands upon how the bond graph augments research in biomedical and bio-mechatronics systems.
Автор: Paul Pop; Wajid Hassan Minhass; Jan Madsen Название: Microfluidic Very Large Scale Integration (VLSI) ISBN: 3319295977 ISBN-13(EAN): 9783319295978 Издательство: Springer Рейтинг: Цена: 107130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Coverage includes a topology graph-based model for the biochip architecture, and a sequencing graph to model for biochemical application, showing how the application model can be obtained from the protocol language.
Автор: Peter Wriggers; Thomas Lenarz Название: Biomedical Technology ISBN: 3319595474 ISBN-13(EAN): 9783319595474 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides an overview of new mathematical models, computational simulations and experimental tests in the field of biomedical technology, and covers a wide range of current research and challenges.
Автор: Arvind K. Chavali and Ramesh Ramji Название: Frugal Innovation in Bioengineering for the Detection of Infectious Diseases ISBN: 3319666452 ISBN-13(EAN): 9783319666457 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book introduces readers to the concept of 'frugal innovation' and describes novel low-cost technologies that aid in diagnosing infectious diseases. Rapidly deployable, portable, and affordable diagnostic tools have the potential to tremendously benefit populations in resource-limited settings and improve global health outcomes. Specifically, the book includes the following features:Cutting-Edge Research: Thorough coverage of scientific advances related to frugal bioengineering that have been developed within the last few years. A few examples of technologies covered in detail include low-cost paper-based and CD-based microfluidic diagnostic systems. Industry and Non-Profit Voices: Chapters written by scientists currently working in industry and philanthropic sectors.
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