Mass Spectrometry for Metabolomics, Gonz?lez-Dom?nguez

Автор: Lammerhofer
Название: Metabolomics in Practice: Successful Strategies to Generate and Analyze Metabolic Data
ISBN: 3527330895 ISBN-13(EAN): 9783527330898
Издательство: Wiley
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Описание: Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation.

Автор: Putri, Sastia Prama ; Fukusaki, Eiichiro
Название: Mass Spectrometry-Based Metabolomics: A Practical Guide
ISBN: 1032652241 ISBN-13(EAN): 9781032652245
Издательство: Taylor&Francis
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Автор: Daniel Raftery
Название: Mass Spectrometry in Metabolomics
ISBN: 1493953192 ISBN-13(EAN): 9781493953196
Издательство: Springer
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Цена: 121110.00 T
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Описание:

Part I. Historical and Methodology Overview

1. Overview: of Mass Spectrometry Based Metabolomics: Opportunities and Challenges

G. A. Nagana Gowda and Danijel Djukovic

Part II. Global LC-MS Based Metabolic Profiling

2. Global Metabolic Profiling using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

Yunpeng Qi, Yunlong Song, Haiwei Gu, Guorong Fan, and Yifeng Chai

3. LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping Populations

Camilla B. Hill, Antony Bacic, and Ute Roessner

4. Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry

Young-Mi Go, Karan Uppal, Douglas I. Walker, ViLinh Tran, Lauriane Dury, Frederick H. Strobel, Hйlиne Baubichon-Cortay, Kurt D. Pennell, James R. Roede, and Dean P. Jones

5. Sample Preparation Methods for LC-MS Based Global Aqueous Metabolite Profiling

Antoni Beltran, Sara Samino, and Oscar Yanes

Part III. Global GC-MS and CE-MS Based Metabolic Profiling

6. Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection

Luke C. Marney, Dr. Jamin C. Hoggard, Kristen J. Skogerboe, and Robert E. Synovec

7. Analysis of Mouse Liver Metabolites by GCЧGC-TOF MS

Xue Shi, Xinmin Yin, and Xiang Zhang

8. Metabolite Fingerprinting by Capillary Electrophoresis-Mass Spectrometry

Antonia Garcia, Shama Naz, and Coral Barbas

Part IV. Isotope Labeling Methods

9. Quantitative Metabolomic Profiling using Dansylation Isotope Labeling and Liquid Chromatography Mass Spectrometry

Ruokun Zhou and Liang Li

10. Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis

Hans Fredrik Nyvold Kvitvang, Kеre A. Kristiansen, Stina K. Lien, and Per Bruheim

11. Stable Isotope Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS

Richard M. Higashi, Teresa W-M. Fan, Pawel K. Lorkiewicz, Hunter N.B. Moseley, and Andrew N. Lane

Part V. Targeted Aqueous Metabolite Profiling

12. Multiplexed, Quantitative and Targeted Metabolite Profiling by LC-MS/MRM

Ru Wei, Guodong Li, and Albert B. Seymour

Part VI. Lipid Profiling Methods

13. Multi-Dimensional Mass Spectrometry-Based Shotgun Lipidomics

Miao Wang and Xianlin Han

14. Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics using High Resolution Mass Spectrometry

Mojgan Masoodi and Dietrich A. Volmer

15. Ultra-Performance Liquid Chromatography Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue and Cultured Cells of Different Species

Juan Carlos Garcнa-Caсaveras, Marнa Teresa Donato, and Agustнn Lahoz

Part VII. Profiling Volatile Organic Compounds

16. Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry combined with Chemometric Analysis

Jan W. Dallinga, Agnieszka Smolinska, and Frederik-Jan van Schooten

17. Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs)

Shucha Zhang and Daniel Raftery

Part VIII. Profiling and Imaging using Atmospheric Sampling Methods

Автор: Putri, Sastia Prama
Название: Mass Spectrometry-Based Metabolomics
ISBN: 1482223767 ISBN-13(EAN): 9781482223767
Издательство: Taylor&Francis
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Автор: Winkler Robert
Название: Processing Metabolomics and Proteomics Data with Open Software: A Practical Guide
ISBN: 1788017218 ISBN-13(EAN): 9781788017213
Издательство: Royal Society of Chemistry
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Цена: 252030.00 T
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Описание: Metabolomics and proteomics allow deep insights into the chemistry and physiological processes of biological systems. This book will enable researchers, practitioners and students from different backgrounds to analyze metabolomics and proteomics mass spectrometry data.

Автор: Gonz?lez-Dom?nguez
Название: Mass Spectrometry for Metabolomics
ISBN: 1071626981 ISBN-13(EAN): 9781071626986
Издательство: Springer
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Цена: 102480.00 T
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Описание: This detailed volume provides a comprehensive overview of state-of-the-art metabolomics methods based on mass spectrometry (MS), and their application in food, nutrition, and biomedical research. The chapters assembled herein cover hot topics related to sample preparation, chromatographic and electrophoretic separation, MS-based analysis, as well as data processing and analysis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mass Spectrometry for Metabolomics serves as a timely guide for chemists, biochemists, biologists, nutritionists, clinicians, and other experts working in the growing and exciting field of metabolomics.

Название: Mass spectrometry in metabolomics
ISBN: 1493912577 ISBN-13(EAN): 9781493912575
Издательство: Springer
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Цена: 186330.00 T
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Описание: Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and commonly used analytical methods in metabolomics; because so many different MS systems are used in metabolomics, this volume includes a wide variety such as triple quads, time of flight, Fourier transform ion cyclotron resonance and even simple quadrupole systems. A wide range of studies are described, with samples ranging from blood and urine to tissue and even plants. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry in Metabolomics: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further the dynamic field of metabolomics.

Название: Capillary Electrophoresis-Mass Spectrometry for Metabolomics
ISBN: 178801104X ISBN-13(EAN): 9781788011044
Издательство: Royal Society of Chemistry
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Описание: In this book, the unique features of CE-MS for metabolomics studies are highlighted and a comprehensive overview of recent technological developments is given at a level suitable for researchers working in metabolomics, bioanalytics and biomarker analysis.

Автор: Sanjoy K. Bhattacharya
Название: Metabolomics
ISBN: 1493994875 ISBN-13(EAN): 9781493994878
Издательство: Springer
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Цена: 186330.00 T
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Описание: The volume brings together some of the best experts in the field of modern metabolomics to discuss various techniques used today to study specific metabolite classes, and metabolomics in bacterial systems and mammalian systems. The chapters in this book cover topics such as Isotopic Ratio Outlier Analysis (IROA) for quantitative analysis; cholesterol and derivatives in ocular tissues using LC-MS/MS methods; microbial siderophores analysis by mass spectrometry; the metabolomic study of tissues in Parkinson’s Disease; and NMR analysis in livestock metabolomics. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, tips on troubleshooting and avoiding pitfalls.Cutting-edge and thorough, Metabolomics: Methods and Protocols is an essential resource for any researcher interested in this exciting and evolving field.

Автор: B.J. Nikolau; Eve Syrkin Wurtele
Название: Concepts in Plant Metabolomics
ISBN: 9048174082 ISBN-13(EAN): 9789048174089
Издательство: Springer
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Цена: 213360.00 T
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Описание: Like genomics, which defines genes in a genome irrespective of functionality, metabolomics profiles all metabolites in a biological sample irrespective of the chemical and physical properties of these molecules.

Автор: G. A. Nagana Gowda; Daniel Raftery
Название: NMR-Based Metabolomics
ISBN: 1493996894 ISBN-13(EAN): 9781493996896
Издательство: Springer
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Цена: 144410.00 T
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Описание: This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understanding, biomarker discovery, environmental studies, and drug discovery to nutrition, while NMR methods include global, targeted, and isotope tracer-based techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Capelo-Martнnez Josй-Luis
Название: Emerging Sample Treatments in Proteomics
ISBN: 3030123006 ISBN-13(EAN): 9783030123000
Издательство: Springer
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Цена: 102480.00 T
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Описание: Proteomics is a well-established area of Science; yet with a strong area in constant evolution, namely sample treatment. There few books that currently cover the field of emerging sample treatments in proteomics, this new volume will be the first to cover all emerging and existing studies. This unique book presents the latest advances in the field focusing on emerging trends linked to high-resolution mass spectrometry, technology addressed to treat samples faster and to attempts to simplify the proteome for the reader.