Jorddy Neves Cruz Drug Discovery and Design Using Natural Products 9783031352041

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Автор: Jorddy Neves Cruz (Джордди Невес Круз)
Название: Drug Discovery and Design Using Natural Products
Перевод названия: Джордди Невес Круз: Открытие и разработка лекарств с использованием натуральных продуктов
ISBN: 9783031352041
Издательство: Springer
Классификация:

Преклиническая медицина: фундаментальные науки

Фармакология

Химия

Органическая химия

ISBN-10: 3031352041
Обложка/Формат: Hardback
Вес: 0.00 кг.
Ссылка на Издательство: Link
Поставляется из: Германии
Описание: Historically, natural products have great relevance for the development of new drugs. Natural molecules, in addition to directly providing new compounds with different therapeutic functions have provided scaffolds and a great diversity of structures that serve as inspiration for the design and discovery of new drugs. The great structural complexity and the significant number of natural compounds that can be obtained and their advantages also present some historical problems that need to be overcome. Issues such as difficulty in isolation, difficulty in synthesizing compounds found in nature in the laboratory, screening to evaluate the biological properties of these compounds, and structural optimization to enhance the pharmacological properties of biomolecules; are some of the main difficulties encountered in research with natural products and in the design/discovery of new medicines. Therefore, this book addresses the great scientific advances that provide practical solutions to using natural products to develop new drugs. We address topics related to the genesis of research projects that use natural products to design new drugs. We address the discovery of new species, initial processes for identification and extraction of compounds, isolation and identification of these structures, techniques, and advances in vitro and in vivo methods that support the discovery of new natural drugs, synthesis of new compounds from natural molecules, in silico optimization processes of potentially promising compounds.
Дополнительное описание: Section 1: Genesis of research projects that use natural products to design new drugs.- Chapter title: Drug development projects guided by ethnobotany and ethnopharmacology studies.- Chapter content: In this chapter, the authors will be encouraged to demo

Drug Discovery and Design Using Natural Products, Jorddy Neves Cruz