Biochemistry of collagens, laminins and elastin, Karsdal, Morten (ceo, Nordic Bioscience A/s, Herlev, Denmark)

Автор: Peter Fratzl
Название: Collagen
ISBN: 1441944818 ISBN-13(EAN): 9781441944818
Издательство: Springer
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Цена: 149060.00 T
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Описание: Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule`s many applications in biomaterials and tissue engineering.

Автор: Karsdal, Morten
Название: Biochemistry of Collagens, Laminins and Elastin
ISBN: 0128098473 ISBN-13(EAN): 9780128098479
Издательство: Elsevier Science
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Цена: 99930.00 T
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Описание: Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. . This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease.

Автор: Eugene J. Kucharz
Название: The Collagens: Biochemistry and Pathophysiology
ISBN: 3642761992 ISBN-13(EAN): 9783642761997
Издательство: Springer
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Цена: 104480.00 T
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Описание: Quam magnijicata sunt opera tua, Domine Omnia in sapientia feciti, plena est terra creaturis tuis. Psalm us CIV: XXIV. The days when the answer to the questions "What is collagen and what is it for?" was simple and short are gone. Nowadays, collagen cannot be considered as a single and metabolic inert fibrous protein responsible only for some mechanical proper- ties of tissues. The family of collagen proteins increases rapidly, and new collagens are still being discovered. They differ each from the other, and only the basic amino acid sequence con- taining proline and hydroxyproline is the one constant and unique feature of proteins which are very different in all other aspects. This heterogeneity is related to the variety of their bio- logical functions. The list of physiological aspects involving collagens as well as the number of disorders associated with collagen abnormalities are expanding rapidly. The structure and function of almost every organ are in some way related to connective tissue and to collagens in particular. Our knowledge in this field is significantly growing but is still far from com- plete. The efforts to modify collagen gene expression, structure, and metabolism in order to manage some disorders are a new goal of pharmacology and are a natural sequel of the progress- ing understanding of the pathophysiological role of collagens. This book provides a comprehensive overview of the patho- physiological aspects of collagens with special emphasis on medical problems, i. e.

Автор: A. Bairati
Название: Biology of Invertebrate and Lower Vertebrate Collagens
ISBN: 1468476386 ISBN-13(EAN): 9781468476385
Издательство: Springer
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Цена: 46570.00 T
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Описание: The NATO Scientific Division financed an Advanced Research Workshop aimed at bringing together experts qualified in collagen biology (with morphological, biochemical and genetic specialization) with researchers who are currently studying collagenous tissues of invertebrates and lower vertebrates.

Автор: Robert, Ladislas
Название: Elastin and Elastases, Volume II
ISBN: 0849364299 ISBN-13(EAN): 9780849364297
Издательство: Taylor&Francis
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Цена: 510400.00 T
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Автор: Robert, Ladislas
Название: Elastin and Elastases, Volume I
ISBN: 0849364280 ISBN-13(EAN): 9780849364280
Издательство: Taylor&Francis
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Цена: 357280.00 T
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Автор: Gopalasamudram Ramachandran
Название: Biochemistry of Collagen
ISBN: 1475746040 ISBN-13(EAN): 9781475746044
Издательство: Springer
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Цена: 113190.00 T
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Описание: Collagen is a fascinating protein not only because of its ubiquitous occurrence in multicellular animals, but also because of its unique chemi- cal structure. Follow- ing the consideration of primary and secondary structure of collagen, the three-dimensional arrangement of collagen molecules in the fibrils is covered by Miller in Chapter 3.

Автор: Irit Sagi; Nikolaos A. Afratis
Название: Collagen
ISBN: 1493990942 ISBN-13(EAN): 9781493990948
Издательство: Springer
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Цена: 158380.00 T
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Описание: This detailed volume compiles state-of-the-art protocols that will serve as recipes for scientists researching collagen, an abundant protein with great importance to health and disease, as well as in applications like food, cosmetics, pharmaceuticals, cosmetic surgery, artificial skin, and glue. Beginning with a section on in vitro models for the characterization of collagen formation, the book continues by highlighting large-scale analysis of collagen with mass spectrometry in order to elucidate the proteomics, degradomics, interactomes, and cross-linking of collagen, high resolution imaging approaches for collagen by the use of scanning electron microscopy and multiphoton imaging, as well as the role of collagen during physiological and pathological conditions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: L. Sandberg
Название: Elastin and Elastic Tissue
ISBN: 1468490958 ISBN-13(EAN): 9781468490954
Издательство: Springer
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Цена: 139310.00 T
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Описание: In 1974, the Division of Lung Diseases of the National Heart, Lung, and Blood Institute initiated a targeted research program on "Isolation and Purification of Lung Elastin".

Автор: Ramshaw, Professor John A.m. (csiro - Commonwealth Scientific And Industrial Research) Glattauer, Dr Veronica (csiro - Commonwealth Scientific And Ind
Название: Biophysical and chemical properties of collagen: biomedical applications
ISBN: 075032094X ISBN-13(EAN): 9780750320948
Издательство: Неизвестно
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Цена: 262090.00 T
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Описание:

Biophysical and Chemical Properties of Collagen: Biomedical Applications provides an introduction to the biophysics and chemistry of collagen and its use as a biomedical material in the rapidly changing fields of biomedical device production, tissue engineering and regenerative medicine. Written by experts in the field, this text will be of interest for researchers as well as lecturers and students.