Biomedical Translational Research, Sobti

Автор: Wu A.
Название: Pharmacogenomic testing in current clinical practice
ISBN: 1607612828 ISBN-13(EAN): 9781607612827
Издательство: Springer
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Цена: 204040.00 T
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Описание: While the basic principles of personalized medicine and pharmacogenomics has been covered by numerous texts, there are none to date that focuses on the specific tests themselves that are in current clinical practice and those that are being proposed for implementation in the near future. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory focuses almost entirely on the specifics of each test that is needed to implement these tests into a clinical laboratory. This volume presents the first compilation of the tests currently in routine clinical use. The chapter authors of this unique and invaluable title comprise a range of renowned authorities and investigators who have conducted the essential clinical trials necessary to justify pharmacogenomic testing today. The book is divided into four parts: Basic Concepts, Specific Pharmacogenomic Targets, Drugs that Cause Delayed Hypersensitivity, and Miscellaneous Drugs. Each author provides a pharmacologic background on the target drug, the need for pharmacogenomic testing, and how results can be translated into clinical decisions. Where appropriate, case studies are given to illustrate typical clinical scenarios. An extensive bibliography is provided so that the reader can refer to the original studies. This well-designed resource will appeal to clinical laboratory directors who are contemplating or assigned the task of establishing a pharmacogenomics laboratory and a wide range of clinicians who must interpret results of testing. Focused and immensely useful, Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory is a timely and outstanding contribution to the literature and will be instrumental in defining this rapidly growing field.

Автор: Sobti
Название: Biomedical Translational Research
ISBN: 981164344X ISBN-13(EAN): 9789811643446
Издательство: Springer
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Цена: 186330.00 T
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Описание: This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology.

Автор: Sobti
Название: Biomedical Translational Research
ISBN: 9811688443 ISBN-13(EAN): 9789811688447
Издательство: Springer
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Цена: 186330.00 T
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Описание: The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure.

Автор: Sobti
Название: Biomedical Translational Research
ISBN: 9811692319 ISBN-13(EAN): 9789811692314
Издательство: Springer
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Цена: 186330.00 T
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Описание: This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning.

Автор: Robert Rhoads
Название: miRNA Regulation of the Translational Machinery
ISBN: 3642031021 ISBN-13(EAN): 9783642031021
Издательство: Springer
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Цена: 153720.00 T
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Описание: This book is dedicated to understanding how miRNAs affect translation. It includes chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs.

Автор: Patterson
Название: Translational Cardiology
ISBN: 1627039341 ISBN-13(EAN): 9781627039345
Издательство: Springer
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Цена: 144410.00 T
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Описание: Covering new developments in cellular, viral and non-biological therapies, and with chapters by experts from a range of disciplines, this is an up-to-date survey of the role that circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart.

Автор: Hutton
Название: Pediatric Biomedical Informatics
ISBN: 981109330X ISBN-13(EAN): 9789811093302
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Поставка под заказ.
Описание: The book describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research. The focus is on the authors’ recent practical experiences in establishing an informatics infrastructure in a large research-intensive children’s hospital. This book is intended for translational researchers and informaticians in pediatrics, but can also serve as a guide to all institutions facing the challenges of developing and strengthening informatics support for biomedical research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children.

Автор: Shen
Название: Translational Biomedical Informatics
ISBN: 9811093695 ISBN-13(EAN): 9789811093692
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Поставка под заказ.
Описание: This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.

Автор: Sobti
Название: Biomedical Translational Research
ISBN: 9811643474 ISBN-13(EAN): 9789811643477
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology. The book highlights the applications of artificial intelligence in the diagnosis of infectious diseases and examines the role of system biology approaches for understanding human complexity, variability, and its influence on health and diseases. It presents the applications of flow cytometry in monitoring the progression and treatment of disease. It covers emerging technologies in cancer research, including CRISPR-Cas9, NGS, and nanotechnology. This book is a useful source of information for clinical researchers, basic scientists, biomedical engineers, and computational biologists.

Автор: Gary Hime (Editor), Helen Abud (Editor)
Название: Transcriptional and Translational Regulation of Stem Cells (Advances in Experimental Medicine and Biology)
ISBN: 9400766203 ISBN-13(EAN): 9789400766204
Издательство: Springer
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Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume takes two approaches to this topic - (1) illustrating the general principles outlined above through a series of different stem cell examples - embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.

Автор: Robert Rhoads
Название: miRNA Regulation of the Translational Machinery
ISBN: 364226140X ISBN-13(EAN): 9783642261404
Издательство: Springer
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Цена: 153720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is dedicated to understanding how miRNAs affect translation. It includes chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs.

Автор: Daniel Gioeli
Название: Targeted Therapies
ISBN: 1617797448 ISBN-13(EAN): 9781617797446
Издательство: Springer
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Цена: 186340.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Targeted Therapies highlights changes in the signaling network in response to inhibition of a signaling event. The text illustrates how a mechanistic understanding of the signaling network in cancer is important to developing targeted cancer therapies.