Автор: Davies Kevin Название: Editing Humanity: The CRISPR Revolution and the New Era of Genome Editing ISBN: 1643137638 ISBN-13(EAN): 9781643137636 Издательство: Неизвестно Рейтинг: Цена: 17430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine. If our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington's disease. But this power to "play God" also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change. Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale. Though the birth of the "CRISPR babies" in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.
Автор: Malali Gowda; Ambardar Sheetal; Chittaranjan Kole Название: The Neem Genome ISBN: 3030161218 ISBN-13(EAN): 9783030161217 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This book describes the sequencing efforts for Neem (Azadirachta indica A. Juss), one of the most versatile tropical evergreen tree species. The neem tree is a source of various natural products, including the potent biopesticide azadirachtin and limonoids, which have a broad spectrum of activity against insect pests and microbial pathogens. To identify genes and pathways in neem, three neem genomes and several transcriptomes are studied using next-generation sequencing technologies.
Neem has been extensively used in Ayurveda, Unani and homoeopathic medicine and is often referred to as the ‘village pharmacy’ by natives due to its wealth of medicinal properties.
Besides the description of the genome, this book discusses the neem microbiome and its role in the production of neem metabolites like salanin, nimbin and exopy-azadirachtin under in vitro conditions. It also highlights cell and tissue culture using various neem explants including the leaf, root, shoot, cambium, etc.
Автор: Shengyi Liu; Rod Snowdon; Boulos Chalhoub Название: The Brassica napus Genome ISBN: 3030095835 ISBN-13(EAN): 9783030095833 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This book describes how the genome sequence contributes to our understanding of allopolyploidisation and the genome evolution, genetic diversity, complex trait regulation and knowledge-based breeding of this important crop. Numerous examples demonstrate how widespread homoeologous genome rearrangements and exchanges have moulded structural genome diversity following a severe polyploidy bottleneck. The allopolyploid crop species Brassica napus has the most highly duplicated plant genome to be assembled to date, with the largest number of annotated genes.
Examples are provided for use of the genome sequence to identify and capture diversity for important agronomic traits, including seed quality and disease resistance. The increased potential for detailed ge
ne discovery using high-density genetic mapping, quantitative genetics and transcriptomic analyses is described in the context of genome availability and illustrated with recent examples. Intimate knowledge of the highly-duplicated gene space, on the one hand, and the repeat landscape on the other, particularly in comparison to the two diploid progenitor genomes, provide a fundamental basis for new insights into the regulatory mechanisms that are coupled with selection for polyploid success and crop evolution.
Автор: Ajit Kumar Shasany; Chittaranjan Kole Название: The Ocimum Genome ISBN: 3030073556 ISBN-13(EAN): 9783030073558 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides an overview of the Ocimum genus from its genetic diversity to genome sequences, metabolites and their therapeutic utilities. Tulasi, Ocimum tenuiflorum, as a member of the family Lamiaceae, is a sacred plant in India. The plants of this genus Ocimum are collectively referred to as Basil and holy basil is worshipped in the Hindu religion. Basils are reservoirs of diverse terpenoids, phenylpropanoids and flavonoids, in addition to commercially important aromatic essential oils. In 2016, two working groups in India published the genome sequence in two different genotypes of Ocimum tenuiflorum. To help the readers understand the complexities of the genus and different chemotypes, this book accumulates all the available information on this medicinal plant including the genome. The complete knowledge may enable researchers to generate specific chemotypes in basil either through conventional breeding or development of transgenic lines. It also makes it possible to investigate the medicinal nature of holy basil compared to different species of the same genus.
Автор: Thomas F. Lee Название: The Human Genome Project ISBN: 0306439654 ISBN-13(EAN): 9780306439650 Издательство: Springer Рейтинг: Цена: 81050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
"This is a study of genetic mapping. The first six chapters address ""molecular biology in a historical framework.... Mapping and various kinds ofmaps (genetic, physical, sequence) are discussed.... (Ge"
Автор: Paul Denny; Chittaranjan Kole Название: Genome Mapping and Genomics in Laboratory Animals ISBN: 3662501422 ISBN-13(EAN): 9783662501429 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers genomic research on a large variety of animal systems, contributed by leading scientists worldwide. Covers such animals as the sea-urchin, nematode worm, fruit fly, sea squirts, puffer fishes, medaka fish, African clawed frog, mouse and rat.
Автор: Jonathan Wendel; Johann Greilhuber; Jaroslav Dolez Название: Plant Genome Diversity Volume 1 ISBN: 3709116996 ISBN-13(EAN): 9783709116999 Издательство: Springer Рейтинг: Цена: 148010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Covering basic genetic and molecular topics as well as the latest research, this first part of a new two-volume work assesses sequencing progress so far, with chapters by renowned experts on the characteristics and evolution of `residents` in plant genomes.
Автор: Kole Chittaranjan, Matsumura Hideo, Behera Tusar Kanti Название: The Bitter Gourd Genome ISBN: 3030150615 ISBN-13(EAN): 9783030150617 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book focusing on the bitter gourd genome is the first comprehensive compilation of knowledge on the botany, cytogenetical analysis, genetic resources and diversity, traditional breeding, tissue culture and genetic transformation, whole genome sequencing and comparative genomics in the Cucurbitaceae family.
Автор: Mondal Tapan Kumar Название: Tea: Genome and Genetics ISBN: 9811588678 ISBN-13(EAN): 9789811588679 Издательство: Springer Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is intended for periodontal residents and practicing periodontists who wish to incorporate the principles of moderate sedation into daily practice. Comprehensive airway management and rescue skills are then documented in detail so that the patient may be properly managed in the event that the sedation progresses beyond the intended level.
Автор: Ithnin Maizura, Kushairi Ahmad Название: The Oil Palm Genome ISBN: 3030225488 ISBN-13(EAN): 9783030225483 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book compiles the fundamental advances resulting from of oil-palm genome and transcriptome sequencing, and describes the challenges faced and strategies applied in sequencing, assembling and annotating oil palm genome sequences.
Автор: Nirala Ramchiary; Chittaranjan Kole Название: The Capsicum Genome ISBN: 3319972162 ISBN-13(EAN): 9783319972169 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book contains complete information on Capsicum genetic resources, diversity, evolution, history and advances in capsicum improvement from classical breeding to whole genome sequencing, genomics, databases and its impact on next generation pepper breeding. Capsicum is one of the most important Solanaceae crops grown worldwide as vegetables and spices. Due to its high economic value and to meet the demands of enormous population growth amid biotic and abiotic stresses, there has been an ongoing breeding program utilizing available genetic resources with desired traits to increase the sustainable productivity of this crop for several decades. However, the precision breeding of this crop for desired traits only started with the advent of molecular markers. The recent advances in high-throughput genome sequencing technologies helped in the quick decoding of transcriptome, epigenome, nuclear and organeller genomes, thereby enhancing our understanding of the structure and function of the Capsicum genome, and helping in genomics assisted breeding. These advanced technologies coupled with conventional mapping have greatly contributed towards dissection and manipulation of economically important traits more precisely and made less time consuming.
Автор: Pierre Pontarotti Название: Evolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life ISBN: 3319378473 ISBN-13(EAN): 9783319378473 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book includes the most essential contributions presented at the 17th Evolutionary Biology Meeting in Marseille, which took place in September 2013.
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