Автор: Lynn B. Jorde, John C. Carey , Michael J. Bamshad Название: Medical Genetics, 6 ed. ISBN: 0323597378 ISBN-13(EAN): 9780323597371 Издательство: Elsevier Science Рейтинг: Цена: 58380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Up to date and extensively revised to reflect recent advances in the genetics of common diseases, as well as current progress in gene therapy, Medical Genetics, 6th Edition, delivers easy-to-read, highly visual coverage of this rapidly changing field. This accessible, practical text integrates key concepts with clinical practice, highlighted by numerous illustrations, tables, concept summaries, and more - all designed to enhance effective learning and retention of complex material.
Discusses current topics
including polygenic risk scores and their potential applications for diabetes, cancer, and heart disease, and the latest sequencing technologies and their clinical application in genetic testing and diagnosis.
Offers a completely updated discussion of genetic testing modalities and applications.
Includes convenient concept summaries, more than 230 photographs, illustrations, and tables, as well as patient/family vignettes that present valuable perspectives on disease and treatment.
Features Clinical Commentary boxes that demonstrate how the hard science of genetics has real applications to everyday patient problems, preparing you for problem-based integrated courses.
Illustrates key concepts with disease examples to demonstrate relevance to medicine.
Provides study questions for self-assessment, as well as 200 additional USMLE-style questions online.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Автор: Eberhard Passarge Название: Color Atlas of Genetics, 5 еd. ISBN: 3132414409 ISBN-13(EAN): 9783132414402 Издательство: Thieme Verlagsgruppe Рейтинг: Цена: 71560.00 T Наличие на складе: Нет в наличии. Описание:
Ever since the International Human Genome Project achieved its extraordinary goal of sequencing and mapping the entire human genome, represented by approximately 3 billion base pairs, with its far-reaching implications for understanding the causes of human genetic disorders and their diagnosis, progress in the field has not slowed down.
In the fifth edition of the bestselling Color Atlas of Genetics, readers will be rewarded with a complete and current overview of the field, with an emphasis on the interface between fundamental principles and practical applications in medicine and the role of signaling pathways in causing diseases.
Using the acclaimed Flexibook format designed for easy visual learning and retention, the atlas is invaluable for students, clinicians, and scientists interested in staying up to date in this fast-evolving area.
New fully illustrated topics in the revised fifth edition of the atlas include:
An overview of disorders resulting from structural changes of the genome (genomic disorders)
Abnormal imprinting patterns
Examples of impaired signal pathways (laminopathies, fibrillinopathies, cohesinopathies, and others)
The CRISPR-Cas system
Genetic features of the aging processes
Disorders due to rearrangements of chromatin in the cell nucleus, and others
With almost 200 stunning color plates explained by concise texts on the opposite pages, including tables presenting useful data, a glossary of terms, key references, and online resources, the atlas presents clear and accessible concepts. It is an excellent refresher for investigators in any field of medicine or biology.
Автор: Peter D Turnpenny, Sian Ellard, Ruth Cleaver Название: Emery`s Elements of Medical Genetics and Genomics, 16e ISBN: 0702079669 ISBN-13(EAN): 9780702079665 Издательство: Elsevier Science Рейтинг: Цена: 48270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Long recognized as a leading textbook in this fast-moving field, Emery's Elements of Medical Genetics and Genomics offers current, complete information with a strong basis in practical clinical genetics and genomics for medical school and beyond. The 16th Edition of this award-winning text has been thoroughly updated throughout and includes case-based and multiple-choice questions, end-of-chapter summaries, an extensive glossary, and convenient online access, making it an ideal choice for all medical undergraduates as well as postgraduates seeking to improve their understanding and knowledge.
Includes new case-based studies with questions and answers throughout, in addition to multiple-choice self-assessment questions for study and review.
Covers key topics such as pharmacogenetics, personalized medicine, prenatal testing, reproductive genetics, and ethical and legal issues in medical genetics.
Divides the text into three easy-to-use sections: The Scientific Basis of Human Genetics, Genetics in Medicine and Genomic Medicine, and Clinical Genetics, Counseling and Ethics
Features full-color illustrations and other images that help readers visualize the appearance of genetic disorders and assist with the understanding of complex genetic structures.
Contains learning features such as summary boxes, an extensive glossary of terms, online hyperlinks to important genetics websites and clinical databases, and more.
Presents the extensive knowledge and experience of distinguished editors Peter D. Turnpenny and Sian Ellard, as well as new editor Ruth Cleaver.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Автор: Robert L. Nussbaum, Roderick R. McInnes Название: Thompson & Thompson Genetics in Medicine ISBN: 1437706967 ISBN-13(EAN): 9781437706963 Издательство: Elsevier Science Рейтинг: Цена: 36450.00 T Наличие на складе: Есть Описание:
Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving field. By integrating the classic principles of human genetics with modern molecular genetics, this medical reference book utilizes a variety of learning tools to help you understand a wide range of genetic disorders.
Acquire the state-of-the-art knowledge you need
on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics.
Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies.
Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos.
Immerse yourself in updated graphics
, full-color text, illustrations, line diagrams, and clinical photos of genetic diseases.
Explore the latest genetic content available in order to remain up to date on the most current trends in the field.
Take advantage of a double-page clinical case study section that demonstrates and reinforces general principles of disease inheritance, pathogenesis, diagnosis, management, and counseling.
Enhance your critical thinking skills and better retain information. Each chapter ends with up to 5 quick genetic problems related to what has just been reviewed, with answers provided in the back of the book.
Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. You'll also access USMLE-style and multiple choice questions.
Автор: Gangane Название: Human Genetics, 5e ISBN: 8131248704 ISBN-13(EAN): 9788131248706 Издательство: Elsevier India Рейтинг: Цена: 6500.00 T Наличие на складе: Есть Описание: The present edition is updated according to the syllabus for undergraduates, recommended by the Medical Council of India. This examination-friendly-book written in simple to-the-point is also useful for postgraduates, immunologists and geneticists. Salient Features Revision in chapters on molecular genetics, chromosomal aberrations, modes of inheritance, population genetics, and genetic counselling to meet current advances in the field Inclusion of new features such as learning objectives facilitate to focus on important facts and key words that form SAQ's in examinationsAddition of new figures and improvement in earlier diagrams to support the utility of this book Additional Feature Complimentary access to enhanced e-book along with online videos.
Автор: Passarge Название: Genetics, Color Atlas ISBN: 3131003634 ISBN-13(EAN): 9783131003638 Издательство: Thieme Verlagsgruppe Цена: 38530.00 T Наличие на складе: Нет в наличии. Описание: A remarkable achievement by a single author...concise but informative...No geneticist or physician interested in genetic diseases should be without a copy of this remarkable edition." --American Journal of Medical GeneticsMore than ever, a solid understanding of genetics is a fundamental element of all medical and scientific educational programs, across virtually all disciplines. And the applications--and implications--of genetic research are at the heart of current medical scientific debates. Completely updated and revised, The Color Atlas of Genetics is an invaluable guide for students of medicine and biology, clinicians, and anyone else interested in this rapidly evolving field. The latest edition of this highly praised atlas retains several popular features, such as the accessible layout and logical structure, in addition to many novel features and 20 completely new color plates on new topics, including:-Cell-to-cell communication, including important signaling and metabolic pathways-Taxonomy of living organisms ("tree of life")-Epigenetic modifications in chromatin-Apoptosis-RNA interference (RNAi)-Comparative genomic hybridization -Origins of cancer-Principles of gene and stem cell therapy, etc.With more than 200 absorbing full-color plates concisely explained on facing pages, the atlas offers readers an easy-to-use, yet remarkably detailed guide to key molecular, theoretical, and medical aspects of genetics and genomics. Brief descriptions of numerous genetic diseases are included, with references for more detailed information.Readers will find that this incomparable book presents a comprehensive picture of the field from its fascinating history to its most advanced applications.Contents Overview:-Introduction-Chronology: important dates in genetics-Part I. Fundamentals: Molecular Basis of Genetics, Prokaryotic Cells and Viruses, Eukaryotic Cells, Mitochondrial Genetics, Formal Genetics, Chromosomes, Regulation and Expression of Genes-Part II. Genomics-Part III. Genetics and Medicine: Cell-to-Cell Interactions, Lysosomes and LDL Receptor, Genes in Embryonic Development, Immune System, Oxygen and Electron Transport, Homeostasis, Maintaining Cell and Tissue Shape, Mammalian Sex Determination and Differentiation, Atypical Inheritance Pattern, Karyotype--Phenotype Correlation, A Brief Guide to Genetic Diagnosis-Guide to Genetic Diagnosis and Map of Important Human Genetic Diseases-Appendix: Supplementary Data in Tables-Glossary
Автор: Naumova Anna K & Taketo-Hosotani Teruko Название: Epigenetics In Human Reproduction And Development ISBN: 9813144262 ISBN-13(EAN): 9789813144262 Издательство: World Scientific Publishing Цена: 121440.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood.
Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.
Автор: Schaaf Название: Human Genetics: From Molecules to Medicine ISBN: 1608316718 ISBN-13(EAN): 9781608316717 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 92670.00 T Наличие на складе: Поставка под заказ. Описание: Human Genetics: From Molecules to Medicine provides balanced coverage of molecular and clinical genetics for the preclinical medical student with relevant examples of the application of basic science to clinical medicine. With its unique, systems-based approach ideal for integrated curricula, the text guides students through their genetics, pediatrics, and medicine rotations and will also be helpful as a pocket resource for residents in pediatrics, internal medicine, family medicine, and obstetrics. Content has been carefully adapted from the critically acclaimed German text for the English language audience.
Автор: Fullerton, Carol S. Название: Posttraumatic Stress Disorder ISBN: 0880487518 ISBN-13(EAN): 9780880487511 Издательство: Mare Nostrum (Eurospan) Цена: 45350.00 T Наличие на складе: Нет в наличии. Описание: This work provides an examination of advances in research and treatment. It incorporates DSM-IV and the diagnostic category acute stress disorder, which emphasizes the breadth of post-traumatic stress symptoms and disorders.
Автор: Stein, Dan J. Название: The American Psychiatric Publishing Textbook of Anxiety Disorders ISBN: 0880488298 ISBN-13(EAN): 9780880488297 Издательство: Mare Nostrum (Eurospan) Цена: 63890.00 T Наличие на складе: Нет в наличии. Описание: A resource for clinicians and researchers on anxiety disorders. It details not only the rigorous diagnostic schemas, underlying psychobiology, and effective pharmacotherapy and psychotherapy interventions developed during the past few decades, but also more recent advances and theoretical and clinical issues in this diverse field. The collection presents the work of 77 US and international experts who cover the phenomenology, aetiology, psychotherapy and pharmacotherapy of every major anxiety disorder (including generalized anxiety disorder, obsessive-compulsive disorder, panic disorder, social phobia and posttraumatic stress disorder). Sample topics include animals models of fear conditioning, which provide parallels with clinical phenomena such as PTSD, and functional brain imaging, which demonstrates that the pharmacotherapy and psychotherapy of OCD are characterized by similar changes, providing an opportunity for integrating the brain and mind. The authors also discuss anxiety disorders in relation to children, adolescents and seniors; different medical settings; substance abuse; and culture and society.
Автор: Gardner, R.j. Mckinlay (adjunct Professor, Clinica Название: Gardner and Sutherland`s chromosome abnormalities and genetic counseling ISBN: 0199329001 ISBN-13(EAN): 9780199329007 Издательство: Oxford Academ Рейтинг: Цена: 124080.00 T Наличие на складе: Поставка под заказ. Описание: Even as classic cytogenetics has given way to molecular karyotyping, and as new deletion and duplication syndromes are identified almost every day, the fundamental role of the genetics clinic remains mostly unchanged. Genetic counselors and medical geneticists explain the "unexplainable," helping families understand why abnormalities occur and whether they're likely to occur again. Chromosome Abnormalities and Genetic Counseling is the genetics professional's definitive guide to navigating both chromosome disorders and the clinical questions of the families they impact. Combining a primer on these disorders with the most current approach to their best clinical approaches, this classic text is more than just a reference; it is a guide to how to think about these disorders, even as our technical understanding of them continues to evolve. Completely updated and still infused with the warmth and voice that have made it essential reading for professionals across medical genetics, this edition of Chromosome Abnormalities and Genetic Counseling represents a leap forward in clinical understanding and communication. It is, as ever, essential reading for the field.
"As a physician who specializes in addiction medicine and drug withdrawal and written widely on them, I recommend Dr. Breggin's book to every health professional who deals with anyone taking psychiatric drugs. He gives highly useful information and reasons for stopping or avoiding them. It's an excellent one-stop source of information about psychiatric drug effects and withdrawal. Prescribers, therapists, patients, and families will benefit from this guidebook." Charles L. Whitfield, MD Bestselling author of "Healing the Child Within" and many other books
"Peter Breggin has more experience in safely withdrawing psychiatric patients from medication than any other psychiatrist. In this book he shares his lifetime of experience. All of our patients deserve the benefit of our obtaining that knowledge." Bertram Karon, PhD Professor of Psychology, Michigan State University Author, The Psychotherapy of Schizophrenia Former President of the Division of Psychoanalysis of the American Psychological Association
"This is such an important book. Describing the problem of withdrawal from psychiatric drugs in detail, and providing clear advice regarding how to deal with this problem as Peter has done so well in this book, is long overdue. For decades, the belief system that is mainstream psychiatry has denied the existence of withdrawal problems from the substances they prescribe so widely. In reality, withdrawal problems with psychiatric drugs is a common occurrence. Because of psychiatry's reckless denial of this real and common problem, millions of people worldwide have not had the support and care they desperately need when attempting to come off psychiatric drugs, often been erroneously advised that these problems are confirmation of the existence of their supposed original so-called 'psychiatric illness.' Dr. Breggin's book is therefore both timely and necessary." Terry Lynch, MD Physician and Psychotherapist Author of "Beyond Prozac: Healing Mental Suffering Without Drugs and Selfhood: A Key to the Recovering of Emotional Well Being," "Mental Health and the Prevention of Mental Health Problems"
"Dr. Peter Breggin has written an invaluable reference for mental health professionals and lay-persons alike who are seeking a way out of dependency on psychiatric drugs. He describes the many dangers of psychiatric medication in straightforward research-based and contextually nuanced terms. Most helpfully, he articulates a method of empathic, person-centered psychotherapy as an alternative to the prevailing emotionally and system disengaged drug-centered approach. In this book, Dr. Breggin systematically outlines how to safely withdraw a patient from psychiatric medication with rich case examples drawn with the detail and sensitivity to individual and situational differences that reveal not only his extensive clinical experience, but his clear, knowledgeable, and compassionate vision of a more humane form of treatment. In this volume, Dr. Peter Breggin has again demonstrated that he is a model of what psychiatry can and should be. This is an indispensable text for both mental health trainees and experienced practitioners seeking a practical alternative to the dominant drug-centric paradigm." Gerald Porter, PhD Vice President for Academic Affairs School of Professional Psychology at Forest Institute
"This much needed book and guide to psychiatric medication withdrawal is clearly written and easy to understand. As people become more empowered and able to inform themselves about the effects of pharmaceuticals, practitioners will be called upon to wean their patients off of damaging medications. This book will provide that guidance. Thank you Dr. Breggin for having the courage to oppose conventional psychiatric thinking and the caring to improve the quality of life for individuals who are ready to experience their own innate healing instead of reaching for a pill to mask the symp
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