Statistical and Computational Pharmacogenomics, Wu, Rongling
Автор: Bertino Joseph S Название: Pharmacogenomics an Introduction and Clinical Perspective ISBN: 0071741690 ISBN-13(EAN): 9780071741699 Издательство: McGraw-Hill Рейтинг: Цена: 88070.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Offers a coverage of all need-to-know topics, from individual molecules to systemic diseases, this book also provides an examination of the latest technologies that are constantly reshaping the field. It also includes general pharmacogenomics and pharmacogenetics concepts, including geneticvariation in signal transduction and targets.
Автор: Wu A. Название: Pharmacogenomic testing in current clinical practice ISBN: 1607612828 ISBN-13(EAN): 9781607612827 Издательство: Springer Рейтинг: Цена: 204040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: While the basic principles of personalized medicine and pharmacogenomics has been covered by numerous texts, there are none to date that focuses on the specific tests themselves that are in current clinical practice and those that are being proposed for implementation in the near future. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory focuses almost entirely on the specifics of each test that is needed to implement these tests into a clinical laboratory. This volume presents the first compilation of the tests currently in routine clinical use. The chapter authors of this unique and invaluable title comprise a range of renowned authorities and investigators who have conducted the essential clinical trials necessary to justify pharmacogenomic testing today. The book is divided into four parts: Basic Concepts, Specific Pharmacogenomic Targets, Drugs that Cause Delayed Hypersensitivity, and Miscellaneous Drugs. Each author provides a pharmacologic background on the target drug, the need for pharmacogenomic testing, and how results can be translated into clinical decisions. Where appropriate, case studies are given to illustrate typical clinical scenarios. An extensive bibliography is provided so that the reader can refer to the original studies. This well-designed resource will appeal to clinical laboratory directors who are contemplating or assigned the task of establishing a pharmacogenomics laboratory and a wide range of clinicians who must interpret results of testing. Focused and immensely useful, Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory is a timely and outstanding contribution to the literature and will be instrumental in defining this rapidly growing field.
Название: Applying Pharmacogenomics in Therapeutics ISBN: 1466582677 ISBN-13(EAN): 9781466582675 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare--i.e., personalized medicine.
Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text:
Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care
Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services
Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases
Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics
Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination.
Автор: Wu, Rongling , Lin, Min Название: Statistical and Computational Pharmacogenomics ISBN: 0367387026 ISBN-13(EAN): 9780367387020 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Невозможна поставка. Описание:
Due to the tremendous accumulation of data for genetic markers, pharmacogenomics, the study of the functions and interactions of all genes in the overall variability of drug response, is one of the hottest areas of research in biomedical science. Statistical and Computational Pharmacogenomics presents recent developments in statistical methodology with a number of detailed worked examples that outline how these methods can be applied. This comprehensive volume provides key tools needed to understand and model the genetic variation for drug response and equips statisticians with a thorough understanding of this complex field and how computational skills can be employed.
Автор: Federico Innocenti; Ron H.N. van Schaik Название: Pharmacogenomics ISBN: 1493959352 ISBN-13(EAN): 9781493959358 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In its new edition, this Methods in Molecular Biology (TM) book covers techniques for interrogating variation in human genes and genomes, assessment of genetic variation in vitro and in vivo and tools for translation and implementation of pharmacogenetic markers.
Автор: Nadine Cohen Название: Pharmacogenomics and Personalized Medicine ISBN: 1617379212 ISBN-13(EAN): 9781617379215 Издательство: Springer Рейтинг: Цена: 186340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Leading experts from the pharmaceutical industry, the scientific community and the government provide guidance for conducting pharmacogenomic research from discovery to the market, while presenting a realistic perspective on the challenges in its application.
Автор: Cai Weimin, Liu Zhaoqian, Miao Liyan Название: Pharmacogenomics in Precision Medicine: From a Perspective of Ethnic Differences ISBN: 9811538972 ISBN-13(EAN): 9789811538971 Издательство: Springer Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs.
Автор: Qing Yan Название: Pharmacogenomics in Drug Discovery and Development ISBN: 1617378259 ISBN-13(EAN): 9781617378256 Издательство: Springer Рейтинг: Цена: 153720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This comprehensive volume explores cutting-edge technologies used to pursue systems-based pharmacogenomics. Extensive chapters follow on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases.
Автор: Cai Weimin, Liu Zhaoqian, Miao Liyan Название: Pharmacogenomics in Precision Medicine: From a Perspective of Ethnic Differences ISBN: 9811538948 ISBN-13(EAN): 9789811538940 Издательство: Springer Цена: 130430.00 T Наличие на складе: Невозможна поставка. Описание: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs.
Автор: Dasgupta, Amitava Название: Pharmacogenomics of Alcohol and Drugs of Abuse ISBN: 1439856117 ISBN-13(EAN): 9781439856116 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Kalow Werner Название: Pharmacogenomics [2nd Ed] ISBN: 1574448781 ISBN-13(EAN): 9781574448788 Издательство: Taylor&Francis Цена: 214370.00 T Наличие на складе: Невозможна поставка. Описание: Reflecting the shift from genetics to genomics in the pharmaceutical sphere, this Second Edition traces the evolution of the science of pharmacogenetics and gathers research from the forefront of the field-spanning the most influential breakthroughs in molecular diagnostics, metabonomics, proteomics, bioinformatics, disease mapping, pharmacodynamics, and disease gene identification.
Автор: Yui-Wing Francis Lam Название: Pharmacogenomics, ISBN: 0123919185 ISBN-13(EAN): 9780123919182 Издательство: Elsevier Science Рейтинг: Цена: 77470.00 T Наличие на складе: Поставка под заказ. Описание: Includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. This book contains review questions for an analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward.
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