Handbook of Assay Development in Drug Discovery, Minor, Lisa K.
Автор: Wood Clive R Название: Antibody Drug Discovery ISBN: 1848166281 ISBN-13(EAN): 9781848166288 Издательство: World Scientific Publishing Рейтинг: Цена: 163680.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Antibody-based therapeutics are a central driver of the success of biopharmaceuticals. The discovery technology of this field is isolated to a limited number of centers of excellence in industry and academia. This title offers guidance to those evaluating and preparing to enter particular areas within the field.
Название: Drug discovery and development, third edition ISBN: 1032084243 ISBN-13(EAN): 9781032084244 Издательство: Taylor&Francis Рейтинг: Цена: 45930.00 T Наличие на складе: Невозможна поставка. Описание: The third edition of The Process of New Drug Discovery and Development presents a practical methodology and up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace.
Автор: Caffrey Название: Parasitic Helminths: Targets, Screens, Drugs and Vaccines ISBN: 3527330593 ISBN-13(EAN): 9783527330591 Издательство: Wiley Рейтинг: Цена: 85710.00 T Наличие на складе: Есть Описание: The first title dealing with drug discovery against parasitic worms (Helminths) which include many of the major human and animal parasites. The book focusses on the development of novel drugs and vaccination strategies making it attractive for academia and industry alike.
Автор: Li Название: The Drug Discovery Experience: Practices, Processes, and Perspectives ISBN: 0470942355 ISBN-13(EAN): 9780470942352 Издательство: Wiley Рейтинг: Цена: 82010.00 T Наличие на складе: Есть Описание: Edited by two distinguished chemists from academia and industry, this book presents an up-to-date overview of major aspects of drug discovery. It covers all ends of the discovery process from target selection to major therapeutic areas.
The development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor. However, few scientists have the multidisciplinary experience needed to control all aspects of an HTS drug discovery project. A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery integrates the experience of diverse experts who offer fundamental and practical guidance across numerous situations.
The book first discusses assay developments for important target classes such as protein kinases and phosphatases, proteases, nuclear receptors, G protein-coupled receptors, ion channels, and heat shock proteins. It next examines assay developments for cell viability, apoptosis, and infectious diseases. The contributors explore the application of emerging technologies and systems, including image-based high content screening, RNA interference, and primary cells. Finally, they discuss the essential components of the integrated HTS process, such as screening automation, compound library management, the screening of natural products from botanical sources, and screening informatics.
Designed to motivate researchers to bring further advances to the field, this volume provides practical guidance on how to initiate, validate, optimize, and manage a bioassay intended to screen large collections of compounds. Drawing on the knowledge from experts actively involved in assay development and HTS, this is a resource that is both comprehensive and focused.
Автор: Thangaraj Parimelazhagan Название: Pharmacological Assays of Plant-Based Natural Products ISBN: 3319268104 ISBN-13(EAN): 9783319268101 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc.
Автор: Weiner Название: Translating Molecular Biomarkers into Clinical Assays ISBN: 3319407929 ISBN-13(EAN): 9783319407920 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.
Автор: Weiner Russell, Kelley Marian Название: Translating Molecular Biomarkers Into Clinical Assays: Techniques and Applications ISBN: 3319821857 ISBN-13(EAN): 9783319821856 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.
Название: Handbook of Chiral Chemicals ISBN: 0367446464 ISBN-13(EAN): 9780367446468 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book discusses various aspects of chiral fine chemicals including their synthesis and uses at scale. It also discusses how the key subclasses of the chiral pool are obtained and covers methods that can be used to introduce or control stereogenic centers.
Автор: Divya Arora; Chetan Sharma; Sundeep Jaglan; Eric L Название: Pharmaceuticals from Microbes ISBN: 3030046745 ISBN-13(EAN): 9783030046743 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Нет в наличии. Описание: This book deals with the noteworthy advancement in the production of bioactive metabolites from microbes and their pharmacological significance. It highlights the pharmacological potential of marine microbes and endophytic fungi and their bioactive secondary metabolites. Emphasis is also given on the significance of probiotics and their specialized molecules in human health and disease as well as their role in dietary intervention for reducing the risk of non-alcoholic fatty liver disease. This work also serves as excellent reference material for researchers, students and academicians in the field of natural product chemistry, pharmacology and applied microbiology.
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