Автор: Bradley J. Название: Nelson`s Pediatric Antimicrobial Therapy 2022. 28 ed. ISBN: 1610025644 ISBN-13(EAN): 9781610025645 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 46200.00 T Наличие на складе: Нет в наличии. Описание: Completely updated and revised, the 28th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help select the best of all antimicrobial choices.
Автор: Charles J. Gomer Название: Photodynamic Therapy ISBN: 1493957309 ISBN-13(EAN): 9781493957309 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Biological interactions of visible light with photosensitizers have been studied for over a century while controlled clinical applications of light and photosensitizers to treat solid tumors, known as photodynamic therapy, have been evolving since the mid 1970’s. In Photodynamic Therapy: Methods and Protocols, leading PDT scientists and clinicians provide the first comprehensive collection of methods and protocols specifically related to relevant mechanistic, dosimetric, preclinical, and clinical procedures used in current PDT research. Reflecting the growing number of studies demonstrating that immunological, tumor microenvironmental, and vascular responses are all contributing to PDT treatment outcomes, the contents of this volume move beyond the more traditional PDT concepts in order to investigate the numerous signal transduction and cell death pathways involved. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Photodynamic Therapy: Methods and Protocols is an ideal guide for new investigators just starting out in PDT research as well as seasoned investigators changing the direction of their research with the intention of exploring this vital field of study.
Автор: Broekgaarden Mans, Zhang Hong, Korbelik Mladen Название: Photodynamic Therapy: Methods and Protocols ISBN: 1071620983 ISBN-13(EAN): 9781071620984 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Part I: In Vitro and In Vivo Models to Study Photodynamic Therapy
1. Application of Monolayer Cell Cultures for Investigating Basic Mechanisms of Photodynamic Therapy
Mans Broekgaarden
2. The Negative Impact of Cancer Cell Nitric Oxide on Photodynamic Therapy
Jonathan M. Fahey and Albert W. Girotti
3. Microtumor Models as a Preclinical Investigational Platform for Photodynamic Therapy
Mans Broekgaarden and Jean-Luc Coll
4. A Microfluidic Model to Evaluate Photodynamic Therapy Treatment Response in 3D Tumors
Shubhankar Nath, Michael Pigula, Tayyaba Hasan, and Imran Rizvi
5. Analysis of Treatment Effects on Structurally Complex Microtumor Cultures Using a Comprehensive Image Analysis Procedure
Anne-Laure Bulin, Mans Broekgaarden, and Tayyaba Hasan
6. High-Throughput Examination of Therapy-Induced Alterations in Redox Metabolism in Spheroid and Microtumor Models
Mans Broekgaarden, Anne-Laure Bulin, and Tayyaba Hasan
7. Spatiotemporal Tracking of Different Cell Populations in Cancer Organoid Models for Investigations on Photodynamic Therapy
Anne-Laure Bulin and Tayyaba Hasan
8. Generating Large Numbers of Pancreatic Microtumors on Alginate-Gelatin Hydrogels for Quantitative Imaging of Tumor Growth and Photodynamic Therapy Optimization
Nazareth Milagros Carigga Gutierrez, Tristan Le Clainche, Jean-Luc Coll, Lucie Sancey, and Mans Broekgaarden
9. The Chicken Embryo Chorioallantoic Membrane as an In Vivo Model for Photodynamic Therapy
Jaroslava Joniovб and Georges Wagniиres
10. Subcutaneous Xenograft Models for Studying PDT In Vivo
Girgis Obaid and Tayyaba Hasan
11. In Vivo Models for Studying Interstitial Photodynamic Therapy of Locally Advanced Cancer
Gal Shafirstein, Emily Oakley, Sasheen Hamilton, Michael Habitzruther, Sarah Chamberlain, Sandra Sexton, Leslie Curtin, and David A. Bellnier
12. Orthotopic Models of Pancreatic Cancer to Study PDT
Girgis Obaid, Zhiming Mai, and Tayyaba Hasan
13. An Orthotopic Murine Model of Peritoneal Carcinomatosis of Ovarian Origin for Intraoperative PDT
Thierry Michy, Claire Bernard, Jean Luc Coll, and Vйronique Josserand
14. Photodynamic Treatments for Disseminated Cancer Metastases Using Fiber-Optic Technologies
Eric M. Kercher and Bryan Q. Spring
15. Stereotaxic Implantation of F98 Cells in Fischer Rats: A Syngeneic Model to Investigate Photodynamic Therapy Response in Glioma
Anne-Laure Bulin, Jean-Franзois Adam, and Hйlиne Elleaume
Название: Resistance to photodynamic therapy in cancer ISBN: 3319127292 ISBN-13(EAN): 9783319127293 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic therapy is a minimally invasive therapeutic procedure that can exert a selective or preferential cytotoxic activity toward malignant cells. The procedure involves administration of an intrinsically non-toxic photosensitizing agent (PS) followed by irradiation at a wavelength corresponding to a visible absorption band of the sensitizer. In the presence of oxygen, a series of events lead to direct tumor cell death, damage to the microvasculature, and induction of a local inflammatory reaction. Studies reveal that PDT can be curative, particularly in early stage tumors and this volume explores the potential of PDT, but also reveals strategic approaches to overcome resistance in tumor cells.
Автор: Nelson John D. Название: 2020 Nelson`s Pediatric Antimicrobial Therapy, 26th Edition ISBN: 1610023528 ISBN-13(EAN): 9781610023528 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 37890.00 T Наличие на складе: Нет в наличии. Описание: The 26th edition provides practical, evidence-based recommendations from the experts in antimicrobial therapy for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help health care providers select the best of all antimicrobial choices.
Drug descriptions cover pediatric-appropriate antimicrobial agents available today and include complete information about dosing regimens.
New in the 26th edition:
First pediatric approval of beta-lactam/beta-lactamase inhibitor for CRE (carbapenem-resistant enteric bacilli), ceftazidime-avibactam
Replacement antibiotics for cefotaxime (lack of availability in the US), including ceftriaxone and cefepime (for neonates)
Situations in which ceftaroline is preferred over vancomycin by the Editors for MRSA infections
Updates on management of influenza, including baloxavir (now approved for children >12 years)
New approaches to treatment of mucomycosis
New recommendations for malaria
More than 150 new references
Автор: Sara Bobone Название: Peptide and Protein Interaction with Membrane Systems ISBN: 3319064339 ISBN-13(EAN): 9783319064338 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria.
Автор: Sara Bobone Название: Peptide and Protein Interaction with Membrane Systems ISBN: 331938273X ISBN-13(EAN): 9783319382739 Издательство: Springer Рейтинг: Цена: 87060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria.
Автор: Cantey MD Joseph B., Sauberan Jason, Nelson John D. Название: Nelson`s Neonatal Antimicrobial Therapy ISBN: 1610023188 ISBN-13(EAN): 9781610023184 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 27720.00 T Наличие на складе: Невозможна поставка. Описание: Nelson's Neonatal Antimicrobial Therapy is your go-to reference for treating neonates with infectious diseases. This handy reference provides evidence-based recommendations from leading experts in antimicrobial therapy for the treatment of infectious diseases in neonates.
Get expert advice on
Dosing for neonates, including low-birth-weight newborns
Drug selection for bacterial, fungal, viral and parasitic pathogens
Drug Stewardship
And more
Автор: Wilson John W Название: Mayo Clinic Antimicrobial Therapy ISBN: 0190696923 ISBN-13(EAN): 9780190696924 Издательство: Oxford Academ Рейтинг: Цена: 38530.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The medical management of infectious diseases and antimicrobial therapy can be a daunting task for health care professionals. Infectious diseases experts at Mayo Clinic provide a coordinated, unified approach to infectious disease treatment for the general patient population as well as the complex patients seen at this internationally renowned destination medical center. Over twenty contributors represent the spectrum of infectious disease experience within the Mayo Clinic framework of patient-centered care. Highlights of Mayo Clinic Antimicrobial Therapy: Quick Guide, Third Edition include simplified and thorough drug dosing recommendations for renal function and renal replacement therapies, drugs of choice for specific organisms (including bacteria, fungi, and viruses), and updated and simplified antimicrobial and management recommendations for specific infectious syndromes. New features of the third edition include dosing recommendations for extended infusions and obese and neonatal patient populations and treatment options targeted for hepatitis B and C infections, prosthetic joint infections, post-transplant infections, and infections resulting from bioterrorism. This compact, user-friendly resource brings the specialized knowledge of Mayo Clinic to your fingertips.
Автор: Pace, John L. Название: Biofilms, Infection, and Antimicrobial Therapy ISBN: 082472643X ISBN-13(EAN): 9780824726430 Издательство: Taylor&Francis Рейтинг: Цена: 255200.00 T Наличие на складе: Нет в наличии.
Название: Biofilms, Infection, and Antimicrobial Therapy ISBN: 0367392194 ISBN-13(EAN): 9780367392192 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Нет в наличии. Описание:
Rather than existing in a planktonic or free-living form, evidence indicates that microbes show a preference for living in a sessile form within complex communities called biofilms. Biofilms appear to afford microbes a survival advantage by optimizing nutrition, offering protection against hostile elements, and providing a network for cell-to-cell signaling and genetic exchange.
Biofilms, Infection, and Antimicrobial Therapy provides an in-depth exploration of biofilms, offering broad background information, as well a detailed look at the serious concerns to which biofilm-associated infections give rise.
Prosthetic device infections, such as those involving artificial heart valves, intravascular catheters, or prosthetic joints, are prime examples of biofilm-associated infections. With the increasing use of such devices in the modern practice of medicine, the prevalence of these infections is expected to increase. Unfortunately, one of the most troubling characteristics of microbes found in biofilms is a profound resistance to antimicrobial agents.
As biofilm-associated infections are particularly difficult to treat, they result in significant mortality, morbidity, and increased economic burden. Clearly, a better understanding of the pathogenesis of these infections and improved means for prevention and treatment are urgently needed!
InBiofilms, Infection, and Antimicrobial Therapy, Drs Pace, Rupp, and Finch assemble the contributions of more than 50 of the world's leading authorities on microbial biofilms who present recent findings on antibacterial tolerance and bacterial persistence associated with biofilms and discuses the implications of those findings with regard to human health. They explore the molecular mechanisms of bacterial adherence, biofilm formation, regulation of biofilm maintenance, and cell-to-cell communication and present the latest information on various treatment protocols that should aid physicians in the treatment o
Автор: Bradley John S., Nelson John D. Название: 2021 Nelson`s Pediatric Antimicrobial Therapy ISBN: 1610024443 ISBN-13(EAN): 9781610024440 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 30890.00 T Наличие на складе: Невозможна поставка. Описание: Completely updated and revised, the 27th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children, including COVID-19. For each disease, the authors provide a commentary to help select the best of all antimicrobial choices.
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