Автор: Niazi, Sarfaraz K. Название: Handbook of Biogeneric Therapeutic Proteins ISBN: 0367454815 ISBN-13(EAN): 9780367454814 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Нет в наличии. Описание: Handbook of Biogeneric Therapeutic Proteins is the first book to offer extensive coverage of all aspects of generic and biosimilar biological products, from the scientific basis through the marketing issues. This practical book includes comprehensive information on establishing a manufacturing system and securing regulatory approval for biogeneric
Автор: Vsevolod V. Gurevich Название: Arrestins - Pharmacology and Therapeutic Potential ISBN: 3642411983 ISBN-13(EAN): 9783642411984 Издательство: Springer Рейтинг: Цена: 287330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume in Springer`s authoritative series on experimental pharmacology covers the molecular mechanisms and therapeutic implications of arrestin-mediated signaling, including the potential of re-engineered signaling proteins in the field of gene therapy.
Автор: Smales C. Mark, James David C. Название: Therapeutic Proteins / Methods and Protocols ISBN: 1588293904 ISBN-13(EAN): 9781588293909 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: World-class researchers share their innovative and proven techniques for the production of therapeutic proteins downstream of the discovery stage. The methods use a variety of sources for producing therapeutic proteins, including bacterial and yeast expression systems, and insect and mammalian cells, and then cover the purification of the resulting protein using both state-of-the-art and traditional methods, such as those sourced from plasma. Additional chapters offer methods for the characterization of therapeutic proteins throughout the production process, along with methods and strategies for viral inactivation and protein formulation. The protocols follow the successful Methods in Molecular Biologyв„ў series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Автор: Loewenthal, Del Название: The Handbook of Phototherapy and Therapeutic Photography ISBN: 1032147520 ISBN-13(EAN): 9781032147529 Издательство: Taylor&Francis Рейтинг: Цена: 132710.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Trepper, Terry Название: Systemic Treatment Of Incest ISBN: 0876305605 ISBN-13(EAN): 9780876305607 Издательство: Taylor&Francis Рейтинг: Цена: 56130.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: C. Mark Smales; David C. James Название: Therapeutic Proteins ISBN: 1627038485 ISBN-13(EAN): 9781627038485 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With the recent completion of the sequencing of the human genome, it is widely anticipated that the number of potential new protein drugs and targets will escalate at an even greater rate than that observed in recent years. However, identification of a potential target is only part of the process in developing these new next generation protein-based “drugs” that are increasingly being used to treat human disease. Once a potential protein drug has been identified, the next rate-limiting step on the road to development is the production of sufficient authentic material for testing, charact- ization, clinical trials, and so on. If a protein drug does actually make it through this lengthy and costly process, methodology that allows the production of the protein on a scale large enough to meet demand must be implemented. Furthermore, large-scale production must not compromise the authenticity of the final product. It is also nec- sary to have robust methods for the purification, characterization, viral inactivation and continued testing of the authenticity of the final protein product and to be able to formulate it in a manner that retains both its biological activity and lends itself to easy administration. Therapeutic Proteins: Methods and Protocols covers all aspects of protein drug production downstream of the discovery stage. This volume contains contributions from leaders in the field of therapeutic protein expression, purification, characterization, f- mulation, and viral inactivation.
Автор: Klaus Dembowsky Название: Novel Therapeutic Proteins: Selected Case Studies ISBN: 3527302700 ISBN-13(EAN): 9783527302703 Издательство: Wiley Рейтинг: Цена: 132000.00 T Наличие на складе: Поставка под заказ. Описание: This book describes medical applications of recombinant proteins and monoclonal antibodies, some of which have already been on the market for several years while others have only recently been launched. It also highlights the manufacturing processes for individual products, the strategies that were taken by companies in the clinical development, and the hurdles that were encountered in clinical trials and had to be overcome before approval by regulatory authorities. Finally, this book illustrates strategies to modify and improve the pharmacodynamic and pharmacokinetic properties of naturally occurring proteins thus paving the way for a new era in biotechnology. Foreword written by Jurgen Drews.
Автор: Emmy van Deurzen; Claire ArnoldBaker Название: Existential Perspectives on Human Issues ISBN: 0333987004 ISBN-13(EAN): 9780333987001 Издательство: Springer Рейтинг: Цена: 39120.00 T Наличие на складе: Нет в наличии. Описание: Existential Perspectives on Human Issues offers students, teachers and practitioners alike a definitive handbook for the practice of existential psychotherapy. For the first time leading figures from the existential field have been brought together to discuss a wide range of issues fundamental to human existence and consequently therapeutic work with clients. Divided into four parts, the book presents different dimensions of living; physical, social, personal and spiritual. Each chapter gives a brief overview of the literature on the topic under discussion as well as a historical background. Theory and practice are addressed with case illustrations highlighting particular relevance. Critical considerations, possible drawbacks and research needs are additionally detailed and suggested further reading is given.
Автор: Taylor Название: Taylor`s Diagnostic and Therapeutic Challenges ISBN: 0387223371 ISBN-13(EAN): 9780387223377 Издательство: Springer Рейтинг: Цена: 55890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Addresses clinical problems that pose diagnostic and therapeutic challenges for primary care physicians. Chapters in this book cover the diagnosis of several difficult diseases and disorders, including diabetes mellitus, fatigue, and chronic pain.
Автор: Alain Belanger Название: Therapeutic Electrophysical Agents: An Evidence-Based Handbook ISBN: 1975159586 ISBN-13(EAN): 9781975159580 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 59470.00 T Наличие на складе: Нет в наличии. Описание: The outright practice of therapeutic electrophysical agents at your fingertips – open, learn, and apply!
Pocket-sized and perfect for learning or practice in any setting, Therapeutic Electrophysical Agents: An Evidence-Based Handbook, 4th Edition, instills the expertise with electrophysical agents needed for success in physical therapy. This proven, practical text is built on evidence from the most recent published peer-reviewed scientific and clinical literature, providing a credible and reliable foundation for safe, effective practice. The updated 4th edition features a new, streamlined design that emphasizes essential knowledge and skills in a compact, portable format preferred by today’s busy students and practitioners, accompanied by online resources that simplify conversion and dosimetric calculations to save time while ensuring accurate results.
New pocket-sized format provides fast, easy access to essential information on demand.
New Takeaways feature highlight key elements related to each chapter.
New and easier approach to objective dosimetry through multiple exemplified formulas and calculations.
New recommended reading list loaded with the most recent published meta-analysis, systematic reviews, and randomized controlled trials.
New listing of Indications to optimize therapeutic effectiveness based on best evidence.
Updated Contraindications, Risks, and Precautions for use enhance safety and clinical decision-making.
Updated step-by-step guidance to application.
Updated full-color photos and illustrations clarify concepts and reinforce understanding.
Автор: Chakraborti Название: Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9811654212 ISBN-13(EAN): 9789811654213 Издательство: Springer Рейтинг: Цена: 465840.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy.
Автор: Olga Iranzo, Pierre Rousselot-pailley Название: Peptide And Protein Engineering For Biotechnological And Therapeutic Applications ISBN: 9811261652 ISBN-13(EAN): 9789811261657 Издательство: World Scientific Publishing Рейтинг: Цена: 153120.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Peptides and proteins are crucial biomolecules in life. The manifold functions they carry out range from molecular recognition and signaling to catalysis and immune response. However, the native systems are limited to a reduced toolbox of chemical functionalities as well as tridimensional structures. Widening these toolboxes could pave the way to engineer peptides and proteins with enhanced properties compared to their native counterparts and/or with structures and functions unprecedented in Nature. Advances in the chemical and biological synthesis of peptides and proteins, in computational tools, in molecular biology and in high-throughput screening methods are making this realm possible.This book aims to give an overview of the last developments in the field of peptide and protein engineering. It comprises a collection of chapters that span from the production of simple non-proteinogenic building blocks and peptidic scaffolds of different sizes and structures to more complex systems including peptide-based nanomaterials, enzymes and artificial metalloenzymes. Different strategies are described where chemical and biological tools have been developed and combined to attain the desired properties and sought functionalities.The diverse systems described in this book highlight the progress in this important field and represent the starting points for the development of functional biomolecules, biomaterials and hybrid systems capable of addressing key societal challenges of our times in relevant areas such health, environment and energy.
Казахстан, 010000 г. Астана, проспект Туран 43/5, НП2 (офис 2) ТОО "Логобук" Тел:+7 707 857-29-98 ,+7(7172) 65-23-70 www.logobook.kz
