Adoptive Cellular Immunotherapy of Cancer, Stevenson, H. C.
Автор: Karp Daniel D Название: Handbook of Targeted Cancer Therapy and Immunotherapy ISBN: 1496389131 ISBN-13(EAN): 9781496389138 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 53190.00 T Наличие на складе: Нет в наличии. Описание: A must-have resource for oncologists, researchers, and other cancer care professionals! This comprehensive yet concise reference includes clinical trial results of more than 190 targeted therapy and immunotherapy agents. Immunotherapy trial results expanded Tumor immunology section added Recent landmark trial results incorporated FDA approvals highlighted Approach clinical challenges from any direction. Chapters organized by tumor type, pathway, and drug name. Find information quickly and easily, using a color-coded, intuitive format. Small enough to fit in your lab coat pocket. Or, download the eBook to your smartphone or other device for even more convenient referencing. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
Автор: Ludewig Burkhard, Hoffmann Matthias W. Название: Adoptive Immunotherapy / Methods and Protocols ISBN: 1588294064 ISBN-13(EAN): 9781588294067 Издательство: Springer Рейтинг: Цена: 163040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy.
Автор: Burkhard Ludewig; Matthias W. Hoffmann Название: Adoptive Immunotherapy ISBN: 1617375462 ISBN-13(EAN): 9781617375460 Издательство: Springer Рейтинг: Цена: 163040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients.
Автор: Butterfield Lisa H., Kaufman Howard L., Marincola Francesco M. Название: Cancer Immunotherapy Principles and Practice ISBN: 1620700972 ISBN-13(EAN): 9781620700976 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 238260.00 T Наличие на складе: Нет в наличии. Описание: Cancer Immunotherapy Principles and Practice, from the Society of Immunotherapy of Cancer (SITC), is the authoritative reference on cancer immunobiology and the immunotherapy treatments that harness the immune system to combat malignant disease.Featuring five sections and over 50 chapters covering the Basic Principles of Tumor Immunology, Cancer Immunotherapy Targets and Classes, Immune Function in Cancer Patients, Disease Specific Treatments and Outcomes, and Regulatory Aspects of Cancer Immunotherapy, this book covers all major topics that have shaped the development of immunotherapy and propelled it to its current place at the forefront of cancer treatment innovation. This volume is a comprehensive resource for oncologists and fellows, immunologists, cancer researchers, and related practitioners seeking understanding of the basic science and clinical applications of cancer immunotherapy. As well as presenting the evidence for immune-based cancer treatment, it positions immunotherapy in the context of other available cancer treatments and provides data on response rates, risks, and toxicities across a variety of diseases. Filled with detailed tables, and instructive illustrations, as well as key points for quick reference, Cancer Immunotherapy Principles and Practice simplifies a challenging and dynamic subject.Key Features:Clearly summarizes the basic principles and research supporting cancer immunotherapy clinical translationContains expert guidance and treatment strategies for all immunotherapy classes and agents, including cell-based therapies, monoclonal antibodies, cytokine therapies, checkpoint inhibitors, oncolytic viruses, adjuvant approaches, and treatment combinationsIncludes expert perspectives from leading authorities in the fieldProvides information on all FDA-approved immunotherapies, including clinical management and outcome dataDiscusses clinical aspects of immunotherapy for individual cancer types, including melanoma and other skin cancers, lung cancers, gynecologic cancers, gastrointestinal cancers, hematologic cancers, genitourinary cancers, head and neck cancers, sarcomas, brain and other CNS cancers, breast cancer, and pediatric malignancies.Explains regulatory aspects behind the development and approval of immunotherapy drugs Includes Online Access to the Digital Book
Автор: Newton, Herbert B. Название: Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy ISBN: 0128121009 ISBN-13(EAN): 9780128121009 Издательство: Elsevier Science Рейтинг: Цена: 224570.00 T Наличие на складе: Нет в наличии. Описание: Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. . As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed.
Автор: Rees Robert C. Название: Tumor Immunology and Immunotherapy ISBN: 0199676860 ISBN-13(EAN): 9780199676866 Издательство: Oxford Academ Рейтинг: Цена: 240240.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
Автор: Ghobadi Название: Gene and Cellular Immunotherapy for Cancer ISBN: 3030878511 ISBN-13(EAN): 9783030878511 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Clinical and preclinical exploration of gene and cellular immunotherapy have seen rapid growth and interest with the development and approval of five Chimeric Antigen Receptor T-cell (CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell Engager (BiTE) for acute lymphoblastic leukemia (ALL). These advances have dramatically improved the management of patients with relapsed refractory lymphoma, myeloma and leukemia. Gene and Cellular Immunotherapy for Cancer offers readers a comprehensive review of current cellular and gene-based immunotherapies. Divided into eighteen cohesive chapters, this book provides an in-depth and detailed look into cellular-based immunotherapies including CAR-T, TCR-T, TIL, Viral CTLs, NK cells in addition to T/NK cell engagers, focusing on their historical perspectives, biology, development and manufacturing, toxicities and more. Edited by two leading experts on gene and cellular immunotherapy, the book will feature chapters written by a diverse collection of recognized and up-and-coming experts and researchers in the field, providing oncologists, immunologists, researchers and clinical and basic science trainees with a bench to bedside view of the latest developments in the field.
Название: Gene and Cellular Immunotherapy for Cancer ISBN: 3030878481 ISBN-13(EAN): 9783030878481 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Part I: Overview
1. The History of Cellular Therapies
2. Basics of Immunity
Part II: CAR-T
3. Biology of CAR-T
4. Cell Types Used for CAR-T Generation
5. Combination Therapeutics with CAR-T Cell Therapy
6. Safety Switches Used for Cellular Therapies
7. Off the Shelf CAR-T
8. Manufacturing of CAR-T Cells: the Assembly Line
9. Navigating Regulations in Gene and Cell Immunotherapy
10. Bringing CAR-T to the Clinic
11. CAR-T Cell Complications
12. Mechanisms of Resistance and Relapse after CAR-T Cell Therapy
Part III: TIL
13. Tumor Infiltrating Lymphocytes (TIL): From Bench to Bedside
Part IV: TCR
14. T-cell Receptor (TCR) Engineered Cells and Their Transition to Clinic
Part V: Viral CTLs
15. Viral Cytotoxic T Lymphocytes (CTLs): from Bench to Bedside
Part VI: NK Cell
16. Biology of NK Cells and NK Cells in Clinic
Part VII: T/NK cell engagers
17. Biology and Clinical Evaluation of T/NK Cell Engagers
Part VIII: Logistics
18. Roadmap for Starting an Outpatient Cellular Therapy Program
Название: Immunotherapy of cancer ISBN: 4431550305 ISBN-13(EAN): 9784431550303 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy has been investigated worldwide as the fourth line of cancer treatment after the standard treatments of surgery, chemotherapy, and radiotherapy. The progress in fundamental understanding of tumor immunology and the recent advances in clinical trials have opened new avenues with a cancer vaccine in 2010 and immunocheckpoint modulation in 2011, with their approval already granted in the United States. Today, there are no doubts, even among experts in cancer chemotherapy and radiotherapy, that the immune system plays a vital role in tumor eradication. Following American approval, many clinical trials of cancer immunotherapy are being conducted. With this book the reader will readily understand the paradigm shift in cancer treatment and will realize the importance of cancer immunotherapy. The great value of immunotherapy will be obvious, not only for tumor shrinkage but for prolonging patient survival.
Автор: Damodaran, Senthil Название: Handbook of targeted cancer therapy and immunotherapy: breast cancer ISBN: 1975184564 ISBN-13(EAN): 9781975184568 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 63730.00 T Наличие на складе: Нет в наличии. Описание: Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy: Breast Cancer provides a practical overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Senthil Damodaran and Debu Tripathy of MD Anderson Cancer Center helps you filter and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of approved or investigational targeted agents and combinations of agents.
Covers breast cancer targets—Phase 1, 2, and 3 trials and preliminary results, as well as approved therapies.
Includes sections on Molecular Targets and Pathways, and Targeted and Immunotherapy Agents.
Contains a section on Molecular Diagnostics, Testing, and Interpretation, with essential content customized for breast cancer.
Organizes information by tumor type, pathway, and drug name, so you can approach clinical challenges from any direction.
Highlights FDA approvals throughout.
Pocket-sized and color coded to help you find information quickly and easily.
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Read directly on your preferred device(s), such as computer, tablet, or smartphone.
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Автор: Teplow, David Название: Cancer Immunotherapy ISBN: 0128165758 ISBN-13(EAN): 9780128165751 Издательство: Elsevier Science Рейтинг: Цена: 150470.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Cancer Immunotherapy, Volume 165 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to different approaches to cancer immunotherapy, with this release focusing on TNFR2 in cancer immunology and immunotherapy, From the Hellstrom paradox towards cancer cure, CAR T-cell treatment of T-cell malignancy, Immunotherapy of pancreatic cancer, Cancer stem cell immunology/immunotherapy,
Cytokine release syndrome, Tumor cell-based mechanisms of resistance to immune attack, and Mushroom compounds in cancer immunotherapy.
Includes comprehensive coverage of molecular biology
Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided
Contains contributions from renowned experts in the field
Автор: Mary L. Disis Название: Immunotherapy of Cancer ISBN: 1617376450 ISBN-13(EAN): 9781617376450 Издательство: Springer Рейтинг: Цена: 243800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practical treatments.
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