Imaging from Cells to Animals In Vivo, Barroso, Margarida
Автор: Thomas Harry Sharp Название: Biomolecular Imaging at High Spatial and Temporal Resolution In Vitro and In Vivo ISBN: 3319350234 ISBN-13(EAN): 9783319350233 Издательство: Springer Рейтинг: Цена: 87060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With concise coverage of light- and electron-based microscopy, including new cryoelectron techniques, this readily consultable guide allows researchers to make informed decisions on which technique to use, and shows them how to interpret the resulting imagery.
Название: In Vivo Optical Imaging of Brain Function ISBN: 0367385651 ISBN-13(EAN): 9780367385651 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Невозможна поставка. Описание:
These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques.
New in the Second Edition:
Voltage-sensitive dyes imaging in awake behaving animals
Imaging based on genetically encoded probes
Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping
Using pH-sensitive dyes for functional mapping
Modulated imaging
Calcium imaging of neuronal activity using 2-photon microscopy
Fourier approach to optical imaging
Fully updated chapters from the first edition
Leading Authorities Explore the Latest Techniques
Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.
Автор: Stefan Geyer; Robert Turner Название: Microstructural Parcellation of the Human Cerebral Cortex ISBN: 3642378234 ISBN-13(EAN): 9783642378232 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book illustrates how state-of-the-art high-field magnetic resonance imaging (MRI) technologies can generate in living brains individual-specific maps of cortical microstructure that are based on differential grey matter myelination between areas.
Автор: Stefan Geyer; Robert Turner Название: Microstructural Parcellation of the Human Cerebral Cortex ISBN: 3642430767 ISBN-13(EAN): 9783642430763 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.
Cancer is fast becoming one of the main causes of death worldwide. Unfortunately many cases are diagnosed at an advanced incurable stage, and these lives are usually lost. Early diagnosis and treatment are very important for increasing disease curability. In recent years, novel techniques for cancer diagnosis and therapy have been developed, and nanobiomedicine appears to show the most promising results.
The application of nanotechnology to biology and medicine in cancer diagnosis is termed nanobiomedicine. Nanoparticles 1-100 nm in size usually have unique physical and/or chemical properties, and this has attracted great attention in the cancer research. Preparation and biomedical applications of the nanoparticles are key components in nanobiomedicine. Semiconductor nanocrystals, including quantum dots (QDs) and quantum rods (QRs), have been extensively investigated for drug delivery, biomedical imaging and tumor target therapy.
In Semiconductor Quantum Dots and Rods for In Vivo Imaging and Cancer Phototherapy, the QD and QR optical properties, sentinel lymph node mapping, in vivo tumor target imaging, self-illuminating QDs for in vivo imaging, in vivo cancer photothermal therapy and photodynamic therapy, QD-graphene nanosheet, and QD-magnetic hybrid nanocomposites for bioimaging and cancer therapy are discussed. This book may interest under- and postgraduate students in the field of bioengineering (especially cancer phototherapy) and medical professions alike.
Название: Bits of life ISBN: 0295997117 ISBN-13(EAN): 9780295997117 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 91960.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Since World War II, the biological and technological have been fusing and merging in new ways, resulting in the loss of a clear distinction between the two. This entanglement of biology with technology isn't new, but the pervasiveness of that integration is staggering, as is the speed at which the two have been merging in recent decades. As this process permeates more of everyday life, the urgent necessity arises to rethink both biology and technology. Indeed, the human body can no longer be regarded either as a bounded entity or as a naturally given and distinct part of an unquestioned whole.
Bits of Life assumes a posthuman definition of the body. It is grounded in questions about today's biocultures, which pertain neither to humanist bodily integrity nor to the anthropological assumption that human bodies are the only ones that matter. Editors Anneke Smelik and Nina Lykke aid in mapping changes and transformations and in striking a middle road between the metaphor and the material. In exploring current reconfigurations of bodies and embodied subjects, the contributors pursue a technophilic, yet critical, path while articulating new and thoroughly appraised ethical standards.
Автор: In-Young Choi; Rolf Gruetter Название: Neural Metabolism In Vivo ISBN: 1489978259 ISBN-13(EAN): 9781489978257 Издательство: Springer Рейтинг: Цена: 217670.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book offers a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain.
Название: In-vitro and in-vivo tools in drug delivery research for optimum clinical outcomes ISBN: 036765721X ISBN-13(EAN): 9780367657215 Издательство: Taylor&Francis Рейтинг: Цена: 50010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers the essentials of drug delivery research and provides a unique forum for scientific experimental methods that are exclusively focused by the in-vitro, ex-vivo, and in-vivo methodologies of drug delivery research and felicitates translational research. The book includes recent and novel approaches in evaluation methods of transde
Автор: Hao Wang; Li-Li Li Название: In Vivo Self-Assembly Nanotechnology for Biomedical Applications ISBN: 9811339007 ISBN-13(EAN): 9789811339004 Издательство: Springer Рейтинг: Цена: 69870.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book reviews and discusses the development of self-assembled nanomaterials applied in biomedical fields. Based on self-assembled nanomaterial constructions, it highlights the mechanisms of the stimuli-response-induced assembly/disassembly and transformation. Moreover, it examines healthcare-related diseases, the applications of nanomaterials and therapy/detection strategies, providing readers with both a deeper understanding of the subject and inspirations for future research. The book is primarily intended for researchers and graduate students in the fields of material sciences and chemistry who wish to learn about the principles, methods, mechanisms and biomedical applications of self-assembled nanomaterials.
Автор: Philippu Название: In Vivo Neuropharmacology and Neurophysiology ISBN: 1493964887 ISBN-13(EAN): 9781493964888 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume presents classical approaches to in vivo neuropharmacology and neurophysiology, such as c-fos, electrochemistry, microdialysis microstimulation, and push-up superfusion. It also explores exciting new methods for behavioral analysis, and techniques based on optogenetics and non-invasive magnetic resonance imaging. The chapters of this book cover topics such as principles of stereotaxy, pharmaco-based fMRI and neurophysiology in humans and non-human primates, electrical nerve stimulation and central microstimulation, involvement of neurotransmitters in mnemonic processes, the impact of cannabinoids on motor activity, as well as the involvement of nitric oxide in neurotoxicity produced by psychostimulant drugs. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.Cutting-edge and practical, In Vivo Neuropharmacology and Neurophysiology is a valuable resource for experienced and less experienced investigators of brain function and brain disorders.
Автор: Alan A. Boulton; Glen B. Baker; Alan N. Bateson Название: In Vivo Neuromethods ISBN: 1617370568 ISBN-13(EAN): 9781617370564 Издательство: Springer Рейтинг: Цена: 163040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A superb collection of time-tested, key techniques for investigating nervous system function, as well as the actions of drugs on the nervous system.
Автор: R.F. Guthoff; C. Baudouin; J. Stave Название: Atlas of Confocal Laser Scanning In-vivo Microscopy in Ophthalmology ISBN: 3662500612 ISBN-13(EAN): 9783662500613 Издательство: Springer Рейтинг: Цена: 107130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Confocal microscopy with laser scanning technology yields in-vivo images of ocular and ocular adnexal surfaces that are so brilliant that they rival histology in terms of quality.This unique atlas and textbook demonstrates normal in-vivo anatomy of the cornea, limbus and conjunctiva, quantifies various cellular structures using cell-density calculations and establishes correlations between novel optical sections of various diseases of the ocular surface and clinical findings. Furthermore, it supports the interpretation of novel high-magnification optical sections by comparing corneal and conjunctival imprint cytology with in-vivo images and describes early inflammatory changes in corneal grafts, as well as corneal conjunctivalisation in limbal stem cell deficiency, corneal dystrophies or infections, flap interface and margin characteristics after laser in-situ keratomileusis (LASIK). In addition, it instructs the reader about diagnostic and therapeutic follow-up strategies and provides a brief introduction to applications in other fields such as dentistry and ear, nose and throat surgery.
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