Annual Reports In Medicinal Chemistry,45, Macor, John E.
Автор: Katja Strohfeldt-Venables Название: Essentials of Inorganic Chemistry: For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry.- Wiley, 2015 ISBN: 0470665580 ISBN-13(EAN): 9780470665589 Издательство: Wiley Рейтинг: Цена: 49580.00 T Наличие на складе: Нет в наличии. Описание: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective.
Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques. This book is ideal for researchers in the areas of biochemistry, medicine, and pharmacology.
Автор: Geoff Lawton Название: Progress in Medicinal Chemistry,52 ISBN: 0444626522 ISBN-13(EAN): 9780444626523 Издательство: Elsevier Science Рейтинг: Цена: 144430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Provides a review of eclectic developments in medicinal chemistry. This volume also provides insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the range of tools now available to solve key scientific problems.
Автор: Harvey Название: Advances in Drug Discovery Techniques ISBN: 0471975095 ISBN-13(EAN): 9780471975090 Издательство: Taylor&Francis Рейтинг: Цена: 0.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A guide to techniques for the discovery and evaluation of pharamcologically active compounds for therapeutic development, this book covers rational drug design, high-throughput screening, and genetic approaches to drug discovery. The authors focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. They examine typical screening studies and their link to robotics and informatics in detail and present an overview of current progress within anitsense therapeutics. The book explores the rapid changes in drug discovery resulting from developments in molecular biology, robotics, and informatics.
Автор: Franco Cataldo Название: Medicinal Chemistry and Pharmacological Potential of Fullere ISBN: 1402068441 ISBN-13(EAN): 9781402068447 Издательство: Springer Рейтинг: Цена: 174150.00 T Наличие на складе: Нет в наличии. Описание: Jacket Description/Back:
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes features important insights into the applications of fullerenes and carbon nanotubes. It discusses the fullerene and nanotubes derivatives which are effective against viruses, cells, and bacteria and those which are able to interact and inhibit certain enzymes. Also covered in this book are the formation of complex structures between biologically active molecules and carbon materials. Furthermore, the application of fullerenes in certain medical therapies is explored, including the very recent discovery of new bio-compatible media which could be used as carriers in the delivery of fullerenes in vivo. An additional topic of this text is the formation of hybrids between nanotubes and biological molecules and their use as chemical sensors.
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes will be a useful tool of reference for researchers, postgraduates and advanced undergraduates in the Chemical, Biomedical, and Materials sciences.
Publisher Marketing:
Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks.
Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances.
In addition, the funtionalization of nanotubes has not only produced relatively simple derivatives, but also complex hybrids with biological macromolecules, which show unique supramolecular architecture and which are promising in many medical applications.
The application of fullerenes and nanotubes in medicine is at the frontier of our knowledge, thus the work in this field represents the basis for future novel developments.
Автор: Watson, David G. (Senior Lecturer in Pharmaceutical Sciences, Strathclyde Institute of Pharmaceutical and Biomedical Sciences, University of Strathcly Название: Pharmaceutical and Medicinal Chemistry. Elsevier,2011 ISBN: 9780443072321\Давид Уотсон:Фармацевтическая и лекарственная химия, Элзивир,2011 ISBN: 0443072329 ISBN-13(EAN): 9780443072321 Издательство: Elsevier Science Рейтинг: Цена: 49390.00 T Наличие на складе: Нет в наличии. Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Автор: Goodnow, Robert Название: Platform Technologies in Drug Discovery and Validation ISBN: 0128130695 ISBN-13(EAN): 9780128130698 Издательство: Elsevier Science Рейтинг: Цена: 154960.00 T Наличие на складе: Нет в наличии. Описание:
Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides.
Автор: Sarker, Satyajit Dey Название: Medicinal Natural Products: A Disease-Focused Approach,55 ISBN: 0128210192 ISBN-13(EAN): 9780128210192 Издательство: Elsevier Science Рейтинг: Цена: 153830.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Medicinal Natural Products: A Disease-Focused Approach, Volume 55 of the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments. Each chapter covers a particular disease area or medical condition - for example, the chapter on anticancer natural products will look into the contributions of natural products in cancer chemotherapy, including the discovery and development of taxol, vincristine and vinblastine as cancer chemotherapeutic agents, and also explore the recent developments in anticancer drug discovery and development from various natural products. All 16 chapters will cover the history, current status and future opportunities of natural products in the treatment and prevention of any particular ailment or medical conditions. Whist the primary focus will be on the medicinal chemistry aspects of these natural products with therapeutic applications, structural modifications and in silico approaches will also be covered. Additionally all chapters will review recent literature of last ten years or so, and present an overview on the developments in respective areas.
Автор: Neidle, Stephen Название: Annual Reports In Medicinal Chemistry,54 ISBN: 0128210176 ISBN-13(EAN): 9780128210178 Издательство: Elsevier Science Рейтинг: Цена: 153830.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.
Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this volume. Drug discovery approaches include both target- and phenotypic whole cell screening- approaches. Regarding the latter, mechanism of action studies through target identification are also illustrated.
Автор: Ward Richard A., Grimster Neil Название: The Design of Covalent-Based Inhibitors ISBN: 0128216891 ISBN-13(EAN): 9780128216897 Издательство: Elsevier Science Рейтинг: Цена: 154960.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Annual Report on Medicinal Chemistry series, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
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