Guidance Molecules In Cancer And Tumor Angiogenesis,114, Daar, Ira
Автор: Yihai Cao Название: Angiogenesis in Adipose Tissue ISBN: 146148068X ISBN-13(EAN): 9781461480686 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers the latest resarch on the critical role of angiogenesis in regulating expansion and regression of adipose tissue, and explores future opportunities for targeting blood vessels as a method for treatment of obesity and metabolic diseases.
Автор: Figg Название: Angiogenesis ISBN: 0387715177 ISBN-13(EAN): 9780387715179 Издательство: Springer Рейтинг: Цена: 222850.00 T Наличие на складе: Поставка под заказ. Описание: Dr Judah Folkman (1933-2008) was considered the `father of angiogenesis`. Because of Folkman`s discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. This book presents a summary of tumor angiogenesis.
Автор: Dieter Marm? Название: Tumor Angiogenesis ISBN: 3319336738 ISBN-13(EAN): 9783319336732 Издательство: Springer Рейтинг: Цена: 372670.00 T Наличие на складе: Поставка под заказ. Описание: This exhaustive work shows that new therapies using anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer, as tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.?
Автор: Dieter Marm? Название: Tumor Angiogenesis ISBN: 3319336711 ISBN-13(EAN): 9783319336718 Издательство: Springer Рейтинг: Цена: 512430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This exhaustive work shows that new therapies using anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer, as tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.
Автор: Domenico Ribatti Название: The Role of Microenvironment in the Control of Tumor Angiogenesis ISBN: 3319278185 ISBN-13(EAN): 9783319278186 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Prelims
1. Tumor microenvironment
1.1. Metastatic cascade
1.2. Epithelial-mesenchymal transition
1.3. The extracellular matrix
2. Tumor blood vessels and tumor endothelial cells
2.1. Tumor basement membrane
2.2. Tumor pericytes
3. Tumor angiogenesis
3.1. Sprouting angiogenesis
3.2. Vascular co-option
3.3. Vasculogenic mimicry
3.4. Intussusceptive microvascular growth
4. Inflammatory cells in tumor microenvironment
4.1. Neutrophils
4.2. Eosinophils and dendritic cells
4.3. Lymphocytes and platelets
4.4. Mast cells
4.5. Macrophages
4.6. Tie-2 expressing monocytes (TEMs)
4.7. Fibroblasts
4.8. Osteoblasts and osteoclasts
4.9. Cancer stem cells (CSCs)
4.10.Circulating endothelial cells and endothelial precursor cells
5. Therapeutic strategies, the concept of "normalization" and the role of VEGF inhibition
Index
Автор: Dieter Marm?; Norbert Fusenig Название: Tumor Angiogenesis ISBN: 3662517981 ISBN-13(EAN): 9783662517987 Издательство: Springer Рейтинг: Цена: 334480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous experts
Автор: Abdel-Majid Khatib Название: Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC`s) ISBN: 9401780900 ISBN-13(EAN): 9789401780902 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importance of protein precursors maturation by the convertases in tumor progression, angiogenesis and metastasis. In each chapter, the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases is discussed. Also this book covers the role of some convertases in the clinical setting. The book will be of interest to basic researchers as well as clinicians. It will also interest those working in the cancer research area and the pharmaceutical industry, who are looking for new strategies in cancer therapy. Finally, this book is also a useful reference for researchers and clinicians pursuing research on growth factors, adhesion molecules, proteases and their implications in the processes of tumor progression, angiogenesis and metastasis.
Автор: Mousa, Shaker Название: Anti-Angiogenesis Strategies in Cancer Therapeutics ISBN: 012802576X ISBN-13(EAN): 9780128025765 Издательство: Elsevier Science Рейтинг: Цена: 77470.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Anti-angiogenesis Strategies in Cancer Therapeutics provides a detailed look at the current status and future directions in the discovery and development of novel anti-angiogenesis strategies in oncology. This book highlights the different mechanisms involved in the modulation of angiogenesis, including inflammation, thrombosis, and microRNA, and shows how nanotechnology can further enhance the potential of existing and new anti-angiogenesis approaches. Written for industry scientists, researchers, oncologists, hematologists, and professors and students in the field, this comprehensive book covers all aspects of anti-angiogenesis strategies and their differences.
Автор: Matthias Kirsch; Peter McL. Black Название: Angiogenesis in Brain Tumors ISBN: 1461346991 ISBN-13(EAN): 9781461346999 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: - Volume is divided into four sections, allowing easy navagation for researchers and practicing physicians- Text includes clinical trials- Written by leaders in the field
Автор: Mukherjee Название: Nanoparticles in Angiogenesis and Cancer ISBN: 3031112830 ISBN-13(EAN): 9783031112836 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book highlights recent developments of organic and inorganic nanomedicine that play a major role in anti-angiogenic cancer therapy. In addition, the authors present examples of nanomedicine based anti-angiogenic agents and their applications in cancer therapy. Angiogenesis is a pathophysiological phenomenon that modulates cell proliferation and cell migration and plays important roles in cancer. Anti-angiogenic nanotherapies have gained immense attention in recent times as alternative cost-effective therapies that opened a new dimension in cancer theranostics. Further the challenges of the anti-angiogenic nanotherapies and possible future perspective are detailed.
Автор: R?diger Liersch; Wolfgang E. Berdel; Torsten Kessl Название: Angiogenesis Inhibition ISBN: 354078280X ISBN-13(EAN): 9783540782803 Издательство: Springer Рейтинг: Цена: 186340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: All aspects from the bench to the bedside are considered in this examination of the latest developments in angiogenesis inhibition in cancer. The authors pay detailed attention both to basic research and to its applications in clinical practice.
Автор: R?diger Liersch; Wolfgang E. Berdel; Torsten Kessl Название: Angiogenesis Inhibition ISBN: 3642261434 ISBN-13(EAN): 9783642261435 Издательство: Springer Рейтинг: Цена: 186340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: All aspects from the bench to the bedside are considered in this examination of the latest developments in angiogenesis inhibition in cancer. The authors pay detailed attention both to basic research and to its applications in clinical practice.
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