Àâòîð: Martelletti Íàçâàíèå: Novel Synthetic Drugs in Migraine ISBN: 3030953335 ISBN-13(EAN): 9783030953331 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 74530.00 T Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: Published in the series Headache, endorsed by the European Headache Federation, this is the first book on the novel synthetic treatment of migraine with ditans (lasmiditan) and gepants (atogepant, ubrogepant, rimegepant, vazegepant). These drugs will provide additional options for people with migraine put at risk of side effects by other medications or with unsatisfactory response to previous drugs. There is now a sufficient amount of literature published to interest a wide multidisciplinary readership (general physicians, general neurologists, clinical psychologists, neurologists in training, and medical students) facing every day this burdensome disorder in their clinical practice. The book aims therefore at offering an overview of these new drugs for both acute and prophylactic treatments of migraine, covering studies on clinical evidence, tolerability, and the different stages of clinical development.
Àâòîð: Jolanta B. Zawilska Íàçâàíèå: Synthetic Cathinones ISBN: 3319787063 ISBN-13(EAN): 9783319787060 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 139750.00 T Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called ?-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.
Àâòîð: Karahan, Mesut Íàçâàíèå: Synthetic peptide vaccine models ISBN: 0367473283 ISBN-13(EAN): 9780367473280 Èçäàòåëüñòâî: Taylor&Francis Ðåéòèíã: Öåíà: 132710.00 T Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes - the future of vaccination. The book illustrates the use of peptides vaccine systems and makes predictions of future development.
Àâòîð: Goran Claeson; Michael F. Scully; Vijay V. Kakkar; Íàçâàíèå: The Design of Synthetic Inhibitors of Thrombin ISBN: 1489924205 ISBN-13(EAN): 9781489924209 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 139750.00 T Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: The symposium was organized in four sessions: (1) Structural features of the interaction of thrombin with substrates and inhibitors, (2) Synthetic inhibitors, (3) Hirudin and its analogues, and (4) Pharmacological and clinical considerations.
Àâòîð: Pavol Kovac Íàçâàíèå: Carbohydrate Chemistry: Proven Synthetic Methods, Volume 1 ISBN: 0367246805 ISBN-13(EAN): 9780367246808 Èçäàòåëüñòâî: Taylor&Francis Ðåéòèíã: Öåíà: 73490.00 T Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: Featuring worldwide contributors and a well-known series editor, the text presents new or older, not easy to find protocols generally useful to those interested in synthetic carbohydrate chemistry.
Antimicrobials: Synthetic and Natural Compounds summarizes the latest research regarding the possibilities of the most important natural antimicrobial compounds derived from various plant sources containing a wide variety of secondary metabolites. With collected contributions from international subject experts, it focuses primarily on natural products as a source of bioactive compounds that may be active against multidrug-resistant pathogens, providing an alternative to established antibiotics in controlling infectious diseases.
Covering a wide range of marine, microbial, and plant-origin antimicrobials, the book examines the usefulness of plant products containing antimicrobial molecules against bacteria, fungi, protozoa, and viruses. It also reports on unusual sources of antimicrobials such as animal fecal actinomycetes, actinobacteria, and cyanobacteria and discusses synthetic chemical compounds and biogenic nanoparticles.
The number of drug-resistant bacteria is increasing, posing a major problem to modern medicine. This book explores an important topic: finding and applying alternative means of pathogenic control and treatment via natural sources. It is an important source of information for microbiologists, biotechnologists, biochemists, pharmacologists, botanists, marine biologists, and others involved in research on natural and synthetic antimicrobial compounds. It is also a useful resource for scholars, scientists, academics, and students in various science disciplines.
Íàçâàíèå: Handbook of Synthetic Antioxidants ISBN: 0367455854 ISBN-13(EAN): 9780367455859 Èçäàòåëüñòâî: Taylor&Francis Ðåéòèíã: Öåíà: 44910.00 T Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: Emphasizes the efficacy of synthetically occurring compounds in the management of free radical-mediated illnesses. The text details the design, development and delivery of therapeutic antioxidants used in the treatment of pathophysiological disorders, from amylotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) to Alzheimer`s disease.
Àâòîð: Bimal K. Banik Íàçâàíèå: Beta-Lactams ISBN: 3319556207 ISBN-13(EAN): 9783319556208 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 139750.00 T Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds.
Àâòîð: Iqbal Ahmad; Shamim Ahmad; Kendra P. Rumbaugh Íàçâàíèå: Antibacterial Drug Discovery to Combat MDR ISBN: 9811398704 ISBN-13(EAN): 9789811398704 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 186330.00 T Íàëè÷èå íà ñêëàäå: Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.
Àâòîð: Banik Bimal K. Íàçâàíèå: Beta-Lactams: Novel Synthetic Pathways and Applications ISBN: 3319857118 ISBN-13(EAN): 9783319857114 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 93160.00 T Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç. Îïèñàíèå: This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds.
