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Drug Repurposing for Emerging Infectious Diseases and Cancer, Sobti


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Цена: 186330.00T
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Автор: Sobti
Название:  Drug Repurposing for Emerging Infectious Diseases and Cancer
ISBN: 9789811953989
Издательство: Springer
Классификация:



ISBN-10: 9811953988
Обложка/Формат: Hardback
Страницы: 654
Вес: 1.37 кг.
Дата издания: 22.02.2023
Язык: English
Издание: 1st ed. 2023
Иллюстрации: 1 illustrations, black and white; xxi, 654 p. 1 illus.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Medicine & Public Health
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.
Дополнительное описание: Chapter 1. Drug repurposing: an advance way to traditional drug discovery.- Chapter 2. Drug polypharmacology towards drug repurposing.- Chapter 3. Pharmacovigilance based drug repurposing.- Chapter 4. In silico analysis of cellular interactors of pqbp1 fo


Nelson`s Pediatric Antimicrobial Therapy 2022. 28 ed.

Автор: Bradley J.
Название: Nelson`s Pediatric Antimicrobial Therapy 2022. 28 ed.
ISBN: 1610025644 ISBN-13(EAN): 9781610025645
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 46200.00 T
Наличие на складе: Нет в наличии.
Описание: Completely updated and revised, the 28th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help select the best of all antimicrobial choices.

Parasitic Helminths: Targets, Screens, Drugs and Vaccines

Автор: Caffrey
Название: Parasitic Helminths: Targets, Screens, Drugs and Vaccines
ISBN: 3527330593 ISBN-13(EAN): 9783527330591
Издательство: Wiley
Рейтинг:
Цена: 85710.00 T
Наличие на складе: Есть
Описание: The first title dealing with drug discovery against parasitic worms (Helminths) which include many of the major human and animal parasites. The book focusses on the development of novel drugs and vaccination strategies making it attractive for academia and industry alike.

Combination Therapies

Автор: E. Garaci; Allan L. Goldstein
Название: Combination Therapies
ISBN: 1461364728 ISBN-13(EAN): 9781461364726
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These molecules, termed biological response modifiers (BRMs) , have been sequenced, synthesized and produced in large enough quantities to test in animals and humans resulting in the development of new approaches to the treatment of human disease, in particular, cancers and infectious diseases.

Drug Repurposing In Cancer Therapy

Автор: To, Kenneth K.W
Название: Drug Repurposing In Cancer Therapy
ISBN: 0128196688 ISBN-13(EAN): 9780128196687
Издательство: Elsevier Science
Рейтинг:
Цена: 176290.00 T
Наличие на складе: Поставка под заказ.
Описание:

Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy.

Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource.


In Silico Drug Design

Автор: Roy, Kunal
Название: In Silico Drug Design
ISBN: 0128161256 ISBN-13(EAN): 9780128161258
Издательство: Elsevier Science
Рейтинг:
Цена: 153830.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design.

  • Discusses the theoretical background and methodologies of useful techniques of cheminformatics and bioinformatics that can be applied for drug repurposing
  • Offers case studies relating to the in silico modeling of FDA-approved drugs for the discovery of antifungal, anticancer, antiplatelet agents, and for drug therapies against diseases
  • Covers tools and databases that can be utilized to facilitate in silico methods for drug repurposing

Surviving Cancer, COVID-19, and Disease: The Repurposed Drug Revolution

Автор: Hope Justus Robert
Название: Surviving Cancer, COVID-19, and Disease: The Repurposed Drug Revolution
ISBN: 0998055425 ISBN-13(EAN): 9780998055428
Издательство: Неизвестно
Рейтинг:
Цена: 30590.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: How does a trained physician beat terminal cancer when he, himself, gets it?


- The answer will both shock and surprise you, as it is often NOT the same treatment that physicians prescribe for their patients.


- Dr. Hope takes you through successful survival stories of doctor after doctor - and he explains how they did it - how they conquered their own terminal cancers.


- This book explains in easy-to-understand words the science behind repurposed drugs, commonly used pills already in your medicine cabinet that can kill cancer stem cells, the roots of cancer. Cancer stem cells are STIMULATED to REGROW and SPREAD and create resistance by standard treatments of chemotherapy, surgery, and radiation - THIS is the reason "cancers return and kill patients almost half the time."


- There are ways to stop cancer stem cells and he explains them in the book.


Dr. Hope wrote this book to help save his friend's life from Glioblastoma, the most aggressive form of brain cancer. But it can also help anyone suffering from terminal cancer. He now shares all of what he found with you:


- Which repurposed drug cocktails to add

- Which diet changes to make

- Which exercises to do

- Which supplements to add

- About IV Vitamin C

- About Fasting

- About IV Vitamin D


All of this is supported by MAINSTREAM SCIENCE.


- The book has been praised by cancer researchers around the world:


- "I consider this a great work." by Marc-Eric Halatsch, MD, PhD, Head, Brain Tumor Research, Ulm University Hospital


- "This is a monumental treatise which should educate and inform...and be of immense benefit to patients with cancer..." George Fareed, MD. Former Assistant Professor Harvard Medical School, Soma Weiss Award for DNA Research


- "This book is an important resource for all cancer patients." Ben Williams PhD, 25 year survivor of Glioblastoma and Professor Emeritus at UC San Diego


This book was written specifically for Dr. Hope's colleague of 30 years to help save him from terminal brain cancer. It can offer ADDITIONAL strategies that can make the difference for anyone suffering from terminal cancer.


"This book should be required reading for all patients when they start chemotherapy." Justus Hope, M.D.


BONUS MATERIAL


  1. An Informed Consent Form for your doctor to provide when requesting repurposed drug prescriptions
  2. A listing of 310 different off-label FDA-approved drugs that have anti-tumor effects
  3. A section on Repurposed Drugs that are effective against the Coronavirus
  4. The famous "Open Letter to Dr. Anthony Fauci" authored by Harvard-trained Dr. George Fareed and discussed in the news

Surviving Cancer, COVID-19, and Disease: The Repurposed Drug Revolution

Автор: Hope Justus R.
Название: Surviving Cancer, COVID-19, and Disease: The Repurposed Drug Revolution
ISBN: 0998055409 ISBN-13(EAN): 9780998055404
Издательство: Неизвестно
Рейтинг:
Цена: 24780.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

ICU specialist Dr. Pierre Kory told the US Senate and the world about the lifesaving repurposed drug, Ivermectin, on December 8, 2021. He called it the solution to the Pandemic. Originally FDA approved to treat parasites; Ivermectin has shown incredible effectiveness against COVID-19. Many people, including actor Louis Gossett Jr or grandmother Judith Smentkiewicz, report rapid turnarounds even from the brink of death.


Dr. Martin Gill says Ivermectin is more effective than any other drug against COVID-19. "I think there is enough evidence now to say this is the drug we have been waiting for. I've been using it literally since April with really spectacular results."


- It is nearly 100% effective at prevention. Dr. Kory notes, "If you take it, you will not get sick." However, its most profound benefits are in hospitalized patients, where it can save even the sickest patients on ventilators.


Perhaps most intriguing is that Ivermectin seems to help prevent the "Long Hauler's Syndrome." This refers to a group of COVID survivors who have long-term problems with lung scarring, shortness of breath or clotting disorders.


- One has to ask the question that if Ivermectin is so effective, then why is it not in widespread use in the US?


The answer is the elephant in the room, and Dr. Kory says he is "severely troubled" by the fact the NIH, the FDA, and the CDC have not reviewed repurposed drugs in an attempt to treat this disease. And that everything has been about expensive and pharmacologically-engineered drugs.


- The problem is that repurposed drugs are not patentable, and therefore are cheap and unprofitable. There is no incentive to study them.


It is revealing that many physicians and privileged scientists in the know already take advantage of repurposed drugs to treat and even cure their own terminal cancers. In the book, Dr. Justus R. Hope describes their stories and how they did it, and how non-physicians can do the same.


- "It is tragically unfair that most people never hear about repurposed drugs."


Dr. Hope aims to change that by making repurposed drugs a household name. "Repurposed drugs in my opinion should be offered in all cases of terminal cancer. They also should have been added long ago as cancer preventative agents."


- In this book, Dr. Hope discusses lifesaving repurposed drugs and supplements that work not just against COVID-19 but against terminal cancer. Specific combinations are reviewed along with referenced studies and supporting scientific evidence.

Originally written to help his friend survive brain cancer, this book is an excellent scientific reference for anyone seeking to find innovative solutions for preventing and treating cancers, viruses, and diseases. It contains an Appendix of 310 repurposed drugs, an Informed Consent Form for your doctor to prescribe them, and resources for patients seeking additional help and information.


The book has been praised by cancer researchers: "I consider this a great work." -Marc-Eric Halatsch, MD, PhD, Head of Brain Tumor Research, Ulm University Hospital, Ulm, Germany



Antibiotic Essentials 2017

Автор: By Cheston B Cunha, By Burke A Cunha
Название: Antibiotic Essentials 2017
ISBN: 9385999079 ISBN-13(EAN): 9789385999079
Издательство: JayPee Brothers
Рейтинг:
Цена: 45410.00 T
Наличие на складе: Нет в наличии.
Описание: The new edition of this highly successful annual pocket guide presents clinicians with the most recent information in the field of antimicrobial therapy and infectious diseases. Written by recognised experts in infectious disease, this edition discusses serum and urinary spectrum summaries of antibiotics and clinically relevant pharmacokinetics. Completely new sections on Antibiotic Stewardship, IV-to-PO Switch Therapy, and differentiation of colonisation and infection, are also included. Unique features of this book include clinical synopses of common and uncommon infections worldwide, differential diagnosis of infectious diseases and non-infectious mimics, antibiotic IV-to-PO switch therapy options for infectious diseases; and HIV, HCV, Peds ID, antibiotic prophylaxis and immunisations, chest film differential diagnosis atlas, and gram stain atlas. Key Points Fifteenth edition presenting most recent information in field of antimicrobial therapy and infectious disease Highly successful annual pocket guide Includes many new topics Authored by leading experts in the field Includes free access to the app

Principles and Practice of Cancer Infectious Diseases

Автор: Safdar
Название: Principles and Practice of Cancer Infectious Diseases
ISBN: 1617797464 ISBN-13(EAN): 9781617797460
Издательство: Springer
Рейтинг:
Цена: 222670.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Here is a thorough update on Infectious Diseases-related issues and emerging concerns. Includes strategies for preventing infections in patients for whom conventional measures may not be as effective as in a non-cancer and non-Stem Cell Transplant population.

Principles and Practice of Cancer Infectious Diseases

Автор: Safdar
Название: Principles and Practice of Cancer Infectious Diseases
ISBN: 1607616432 ISBN-13(EAN): 9781607616436
Издательство: Springer
Рейтинг:
Цена: 222670.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Principles and Practice of Cancer Infectious Diseases is a comprehensive and insightful work dedicated to elucidating the problem of infections in cancer patients. This essential volume reviews common and less often encountered infections, while establishing the difficulties behind preventing, diagnosing, and treating infectious diseases in cancer patients. Key sections are devoted to the presentation of clinical symptoms and the identification of major etiologic agents. A cadre of leading clinicians provide a detailed assessment of the risk factors for various infections, critical strategies in preventing and managing infections, and study of the interactions between the pathogen and host's immune function and inflammatory response. With its in-depth knowledge and concise treatment of the distinct facets of infections in cancer patients, this volume is an indispensible tool for all infectious disease specialists and clinical oncologists.

Microbial Infections and Cancer Therapy

Название: Microbial Infections and Cancer Therapy
ISBN: 9814774863 ISBN-13(EAN): 9789814774864
Издательство: Taylor&Francis
Рейтинг:
Цена: 141890.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book deals with the emerging concept that certain pathogenic bacteria and viruses, when infecting people with cancer, actively fight tumors, allowing their regression. It is composed of 12 chapters written by pioneers in microbial, biotech, and cancer research.

Infections in Cancer Patients

Название: Infections in Cancer Patients
ISBN: 0367394294 ISBN-13(EAN): 9780367394295
Издательство: Taylor&Francis
Рейтинг:
Цена: 61240.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Outlining the best means of infection management and emphasizing early recognition and identification of pathogens, this trailblazing volume pinpoints the distinct immunodeficiencies related to specific malignancies that result in predictable opportunistic infections-containing accessible reviews of the latest scientific research, reports from the forefront of clinical practice, and copious illustrations and tables to be of maximal benefit to the reader.


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