Purinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration, Ulrich

Название: Neuroinflammation and Neurodegeneration
ISBN: 1493910701 ISBN-13(EAN): 9781493910700
Издательство: Springer
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Цена: 186330.00 T
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Описание: State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer’s disease, Parkinson’s disease, stroke, viral encephalitides and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.

Автор: Alireza Minagar
Название: Neuroinflammation,
ISBN: 0123849136 ISBN-13(EAN): 9780123849137
Издательство: Elsevier Science
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Цена: 134610.00 T
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Описание: Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome.

Автор: Rosenberg, Gary (professor Of Neurology And Director, University Of New Mexico Memory And Aging Center, Albuquerque, New Mexico, Usa)
Название: Neuroinflammation in vascular dementia
ISBN: 0128234555 ISBN-13(EAN): 9780128234556
Издательство: Elsevier Science
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Цена: 129130.00 T
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Описание: He is exactly what this age needs, a real voice of universal spirituality. His appeal is urgent, human and sacred. DAN CRUSEY Sidney, Ohio Each era has its own prophet poets. Russia has been praying and is praying poems by Pushkin, a holy name for every Russian. Ayaz seems to touch us with that sensitivity, inspiring and changing the rhythm of our breathing. SEBARITA KAKHOVSKAYA Ukraine His words transform you through a subtle Alchemy process, and you suddenly travel from a Neophyte to the Connoisseur of Mysteries. His poetry is a gateway to the stars ELLURA ZURIA Rhn, Germany Reading Ayaz is akin to a journey into the

Автор: Phillip K. Peterson; Michal Toborek
Название: Neuroinflammation and Neurodegeneration
ISBN: 1493946986 ISBN-13(EAN): 9781493946983
Издательство: Springer
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Цена: 148010.00 T
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Описание: State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration).

Автор: A. Israel; B. de Strooper; F. Checler; Y. Christen
Название: Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate
ISBN: 3642627676 ISBN-13(EAN): 9783642627675
Издательство: Springer
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Цена: 139750.00 T
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Описание: Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders?

Автор: Paul L. Wood
Название: Neuroinflammation
ISBN: 1468497200 ISBN-13(EAN): 9781468497205
Издательство: Springer
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Цена: 174150.00 T
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Описание: There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.

Автор: Ulrich Dirnagl; Bernd Elger
Название: Neuroinflammation in Stroke
ISBN: 3662054280 ISBN-13(EAN): 9783662054284
Издательство: Springer
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Цена: 111790.00 T
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Автор: Suzumura
Название: Neuron-Glia Interaction in Neuroinflammation
ISBN: 1461483123 ISBN-13(EAN): 9781461483120
Издательство: Springer
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Цена: 156720.00 T
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Описание: Accumulation on glia is an active pathological element in many neurological disorders. The proposed book focuses on the interaction between neurons and glia to help elucidate the pathophysiology of neuroinflammation in neurological disorders.ГЇВїВЅ

Автор: Akio Suzumura; Kazuhiro Ikenaka
Название: Neuron-Glia Interaction in Neuroinflammation
ISBN: 1493953648 ISBN-13(EAN): 9781493953646
Издательство: Springer
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Цена: 158380.00 T
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Описание: Accumulation of glia, gliosis, in various neurological disorders is not a static scar, but actively involved in pathogenesis of various neurological and psychiatric disorders, where glial cells produce both inflammatory and neurotrophic factors. These factors may play a role in neuronal damage, but also have a protective and reparative function by inducing neuroinflammation. However, definition as well as the mechanisms of neuroinflammation is not yet clear. We first define acute, chronic and non-classical neuroinflammation. Glial cells are activated by a variety of stimuli via receptors on glial cells. Toll like receptors (TLR) are one of these receptors. In response to harmful stimuli, neurons produce factors as either eat-me or help-me signals. These factors include cytokines, chemokines and damage-associated molecular pattern (DAMP). Some of them activate glial cells via TLR, and function to protect neurons or further induce neuroinflammation. Thus, the interaction between neuron-glia and glia-glia is a main feature of neuroinflammation. Glial cells communicate with other glial or neural cells via gap-junctions. The communication may also be important for the understanding of neuroinflammation. Oligodendrocytes-neurons communication may be critical in either myelination or demyelination. Damage of blood-brain barrier (BBB) is common feature of both inflammatory and degenerative neurological disorders. Thus, relation of BBB damage and functions of glial cell may also be important in the development of neuroinflammation. In this book, we focused on neuron-glia interaction of various aspects for understanding of pathophysiology of neuroinflammation in development of inflammatory as well as degenerative neurological disorders.

Автор: H. Kettenmann; G. Burton; U. Moenning
Название: Neuroinflammation — From Bench to Bedside
ISBN: 3540430903 ISBN-13(EAN): 9783540430902
Издательство: Springer
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Цена: 130430.00 T
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Описание: Introducing neuroinflammation and its involvement in human neurodegenerative disease, this text discusses the microglia and their response to brain injury, the importance of the chemokine family, experimental models of BSE, scrapie and vCJD as well as Alzheimer`s disease, stroke and MS.

Автор: H. Kettenmann; G. Burton; U. Moenning
Название: Neuroinflammation — From Bench to Bedside
ISBN: 3662050757 ISBN-13(EAN): 9783662050750
Издательство: Springer
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Цена: 93160.00 T
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Описание: Inflammatory processes have been implicated in the pathophysiology of a variety of neurodegenerative diseases such as Alzheimer's disease, stroke and mUltiple sclerosis. It is now widely accepted that the brain, considered to be an "immunologically privileged" organ, can exhibit immune and autoimmune responses, and it is these responses that may in fact be responsible for many neural pathologies. The participants of the workshop VI Preface Research over the past decade has demonstrated the pivotal role of the microglia in the neuroinflammatory process, and more recent work in the field of chemokines has firmly established their important role in the pathogenesis of inflammatory disease states. Inevitably with the wealth of research being conducted in the field of neuroinflammation comes the hope of identifying novel targets for therapeutic intervention in the inflammatory process which may im- pact on neurodegenerative diseases. The meeting "Neuroinflammation - From Bench to Bedside" aimed to cover the whole spectrum of research currently being pursued in this exciting field, literally taking the participants from the bench - study- ing the importance of the microglia in the inflammatory process and the involvement, in particular, of the rapidly expanding chemokine family in the pathophysiology of neurodegenerative diseases - to the bedside - and the possibilities for novel treatment of disorders as di- verse as multiple sclerosis, Alzheimer's disease, stroke and variant Creutzfeldt-Jakob disease (vCJD).

Автор: Galswells Alfred
Название: Neuroinflammation: Latest Findings
ISBN: 1632416816 ISBN-13(EAN): 9781632416810
Издательство: Неизвестно
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Цена: 150200.00 T
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