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Matrix Pathobiology and Angiogenesis, Papadimitriou


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Автор: Papadimitriou
Название:  Matrix Pathobiology and Angiogenesis
ISBN: 9783031196157
Издательство: Springer
Классификация:



ISBN-10: 3031196155
Обложка/Формат: Hardback
Страницы: 320
Вес: 0.69 кг.
Дата издания: 03.01.2023
Серия: Biology of Extracellular Matrix
Язык: English
Издание: 1st ed. 2023
Иллюстрации: 1 illustrations, black and white; xxvii, 320 p. 1 illus.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: In the vasculature, the extracellular matrix (ECM) is involved in the regulation of angiogenesis, vascular mechanosensing, and blood vessel stability. This book aims to provide the reader with an overview of the various roles of the ECM during angiogenesis and covers its important role for the maintenance of vascular integrity, capillary and arterial morphogenesis, as well as lymphangiogenesis. Furthermore, aspects of regulation of endothelial cell and pericyte functions by the ECM under physiological and pathological conditions are discussed. In addition, the reader will learn more about different approaches to exploit ECM molecules for designing therapeutic approaches or as biomarkers to improve therapeutic decisions. Comprehensive and cutting-edge, Matrix Pathobiology and Angiogenesis is a valuable resource for experienced researchers and early career scientist alike, who are interested in in learning more about this exciting and developing field. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
Дополнительное описание: Chapter 1: Fibronectin Fibrillogenesis during Angiogenesis.- Chapter 2: Functional Interplay Between Fibronectin and Matricellular Proteins in the Control of Endothelial Tubulogenesis.- Chapter 3: Endothelial Cell-Matrix Interactions in Angiogenesis and V


Nitric Oxide

Автор: Ignarro, Louis J.
Название: Nitric Oxide
ISBN: 0128042737 ISBN-13(EAN): 9780128042731
Издательство: Elsevier Science
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Цена: 207730.00 T
Наличие на складе: Нет в наличии.
Описание: Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. . With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of pharmacology, biochemistry, cell and molecular biology, chemistry, immunology, neurobiology, immunology, nutrition sciences, drug development and the clinical management of both acute and chronic diseases.

Extracellular Matrix: Pathobiology and Signaling

Автор: Nikos Karamanos
Название: Extracellular Matrix: Pathobiology and Signaling
ISBN: 3110258765 ISBN-13(EAN): 9783110258769
Издательство: Walter de Gruyter
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Цена: 271490.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the last decades cell biology and biological chemistry have increasingly turned their attention to the space between cells and revealed an elaborate network of macromolecules essential for structural support, cell migration, adhesion and signaling.

Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome

Автор: Soares
Название: Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome
ISBN: 9048181879 ISBN-13(EAN): 9789048181872
Издательство: Springer
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Цена: 172350.00 T
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Описание: This book reviews and discusses knowledge gathered on Metabolic Syndrome and analyzes the interplay between oxidative stress, chronic inflammation and angiogenesis features. It focuses on recent discoveries and progress toward possible therapeutic strategies.

Nanoparticles in Angiogenesis and Cancer

Автор: Mukherjee
Название: Nanoparticles in Angiogenesis and Cancer
ISBN: 3031112830 ISBN-13(EAN): 9783031112836
Издательство: Springer
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Цена: 93160.00 T
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Описание: This book highlights recent developments of organic and inorganic nanomedicine that play a major role in anti-angiogenic cancer therapy. In addition, the authors present examples of nanomedicine based anti-angiogenic agents and their applications in cancer therapy. Angiogenesis is a pathophysiological phenomenon that modulates cell proliferation and cell migration and plays important roles in cancer. Anti-angiogenic nanotherapies have gained immense attention in recent times as alternative cost-effective therapies that opened a new dimension in cancer theranostics. Further the challenges of the anti-angiogenic nanotherapies and possible future perspective are detailed.

Angiogenesis

Автор: Benest
Название: Angiogenesis
ISBN: 1071620614 ISBN-13(EAN): 9781071620618
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
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Описание: This detailed book builds on the foundation of lymphatic protocols with tools to aid in the interpretation of large datasets created by angiogenesis research. For example, this includes protocols to explore how transcriptional phenotyping can be achieved, both in terms of exploring tissue-specific heterogeneity to the use of database mining of existing datasets. Similarly, bioinformatic techniques run alongside protocols for transcript analysis, cell biology, pathology, as well as physiological and developmental angiogenesis models. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Angiogenesis: Methods and Protocols provides a meaningful compendium of practical approaches to angiogenesis and endothelial cell biology research.

Corneal Angiogenesis

Автор: Gordon K. Klintworth
Название: Corneal Angiogenesis
ISBN: 1461277876 ISBN-13(EAN): 9781461277873
Издательство: Springer
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Цена: 97820.00 T
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Описание: This monograph summarizes current knowledge about angiogenesis within this tissue as well as information about the related issue of the cornea`s normal avascularity.

Angiogenesis in Adipose Tissue

Автор: Yihai Cao
Название: Angiogenesis in Adipose Tissue
ISBN: 146148068X ISBN-13(EAN): 9781461480686
Издательство: Springer
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Цена: 149060.00 T
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Описание: This book covers the latest resarch on the critical role of angiogenesis in regulating expansion and regression of adipose tissue, and explores future opportunities for targeting blood vessels as a method for treatment of obesity and metabolic diseases.

History of Research on Tumor Angiogenesis

Автор: Ribatti
Название: History of Research on Tumor Angiogenesis
ISBN: 9048181569 ISBN-13(EAN): 9789048181568
Издательство: Springer
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Цена: 121890.00 T
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Описание: In 1971, J. Folkman hypothesized that tumor growth is angiogenesis-dependent. In 2004, the FDA approved the first angiogenesis inhibitor. This book compiles the relevant literature of that history and emphasizes the antiangiogenic approach to treat tumors.

Angiogenesis in Health, Disease and Malignancy

Автор: Salajegheh Ali
Название: Angiogenesis in Health, Disease and Malignancy
ISBN: 331980281X ISBN-13(EAN): 9783319802817
Издательство: Springer
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Цена: 139750.00 T
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Описание:

1. Introduction to Angiogenesis in Normal Physiology. Disease and Malignancy

2. Adenosine triphosphate-binding cassette (ABC) lipid transporters

3. Angiogenin

4. Angiopoietins

5. Angiotropin

6. C-KIT: tyrosine kinase receptors with potential to initiate

7. CCND1 and E1

8. Cluster of Differentiation 71 (CD71)

9. Connective Tissue Growth Factor (CTGF)

10. COX10

11. Cysteine-rich 61 (Cyr61)

12. Epidermal growth factor

13. Epidermal growth factor domain-like 7 (EGFL7)

14. Erythropoietin-producing hepatocellular receptors A: Ephrin A1, Ephrin A2 and Ephrin A3

15. Erythropoietin-producing hepatocellular receptors B: Ephrin B2, Ephrin B4

16. Ets-1

17. Fibrin

18. Fibroblast growth factors (Acidic: FGF-1; Basic: FGF-2) and its receptors (FGFR)

19. Fibronectin

20. Granulocyte-Macrophage and Granulocyte Colony Stimulating Factor (GM-CSF and G-CSF)

21. GAX and HOXA5

22. Heparanase

23. Hepatocyte Growth Factor (HGF)

24. HIF-1α

25. Insulin-like growth factor

26. Integrins (αv1β3, αv1β5, β8)

27. Interleukins

28. Insulin receptor substrate (IRS1)

29. Iron-sulfur clusters (ISCU)

30. MDM4

31. Matrix Metalloproteinase 2 (MMP2)

32. Monobutyrin

33. Neutrophil activating protein-2 (NAP-2)

34. p27kip1 and p57Kip2 (CDKN1B and CDKN1C)

35. Platelet-derived endothelial cell growth factor (PDGF)

36. Prolyl hydroxylase domain-2 (PHD-2)

37. Phosphatidylinositol-4, 5-bisphosphate 3-kinase (PIK3Ca)

38. PIK3R2 (p85β) - Phosphatidylinositol 3-kinase β-subunit

39. Platelet-activating factor

40. Placenta growth factor (PlGF)

41. Preproendothelin-1 (PreproET-1)

42. Proliferin

43. Prostaglandins

44. ROS1

45. SIRT1

46. SMAD4 (Mothers against Decapentaplegic Homolog 4)

47. Sprouty-Related, EVH1 Domain-containing protein 1 (SPRED-1)

48. Signal transducer and activator of transcription of 5A and S3 (STAT5 and STATS3)

49. SUFU

50. Tenascins

51. Tissue inhibitor of metalloproteinases 1 and 2 (TIMP-1 and TIMP-2)

52. Tissue factor gene

53. Transforming growth factor α and β (TGF- α and TGF- β)

54. Transforming growth factor beta-receptor type II (TGFβR2)

55. TSP-1

56. Tumour necrosis factor-α (TNF-α)

57. Urokinase plasminogen activator

58. Vascular Endothelial Growth Factor (VEGF)

59. Vascular cell adhesion molecule-1 (VCAM-1)

60. Vascular endothelial (VE)-Cadherin

61. Zinc Finger E-Box Binding Homeobox 1 (ZEB1)

62. Miscellaneous genes involved in Angiogenesis in Normal Physiology, Disease and Malignancy


Angiogenesis Modulations in Health and Disease

Автор: Shaker A. Mousa; Paul J. Davis
Название: Angiogenesis Modulations in Health and Disease
ISBN: 9401785155 ISBN-13(EAN): 9789401785150
Издательство: Springer
Рейтинг:
Цена: 148010.00 T
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Описание: This book offers in-depth explanations of pro-angiogenesis and anti-angiogenesis targets and their evaluation methods. Coverage includes preclinical and clinical methods and models, investigational status, and clinical applications.

Regulation of Angiogenesis

Автор: Goldberg
Название: Regulation of Angiogenesis
ISBN: 3764353090 ISBN-13(EAN): 9783764353094
Издательство: Birkhauser Verlag AG
Цена: 238850.00 T
Наличие на складе: Нет в наличии.
Описание: This volume presents a comprehensive review of current understanding of angiogenesis and angiogenesis control. Topics covered include: important pro-angiogenic growth factors and their receptors; angiogenesis inhibitors; extracellular matrix factors; and the role of the fibrinolytic system.

The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis

Автор: Domenico Ribatti
Название: The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis
ISBN: 9400791577 ISBN-13(EAN): 9789400791572
Издательство: Springer
Рейтинг:
Цена: 104480.00 T
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Описание: 1. Introduction 2. Chorioallantoic membrane and its embryological origin 2.1. Morphology of chorioallantoic membrane blood and lymphatic vessels 2.2. A single blood sinus or a capillary plexus beneath the chorionic epithelium? 2.3. The chorioallantoic membrane vascular growth 3. Use of chorioallantoic membrane in the study of angiogenic molecules 3.1. Role of FGF-2 in chorioallantoic membrane vascularization 4. Use of chorioallantoic membrane in the study of antiangiogenic molecules 5. Use of chorioallantoic membranes in the study of tumor angiogenesis 5.1. Angiogenesis and antiangiogenesis in multiple myeloma 5.2. Angiogenesis and antiangiogenesis in human neuroblastoma 6. Use of chorioallantoic membrane in the study of tumor metastasis 6.1. Spontaneous metastasis models. 6.2. Experimental metastasis studies. 7. Other applications 7.1. In ovo and ex ovo methods 7.2. Use of chorioallantoic membrane in the study of tumor lymphangiogenesis 8. Different morphological techniques that can be used to study vascularization of the CAM and the genes involved. 9. Methods of quantifying the angiogenic response 10. Limitations of the chorioallantoic membrane assay 11. Other classical in vivo assays in comparison (advantages, disadvantages and limitations) with the chorioallantoic membrane 12. Concluding remarks Acknowledgments References


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