The Renin Angiotensin System in Cardiovascular Disease, Dhalla

Автор: Leung
Название: Frontiers in Research of the Renin-Angiotensin System on Human Disease
ISBN: 9048176174 ISBN-13(EAN): 9789048176175
Издательство: Springer
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Описание: The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of renin-angiotensin system (RAS) research that is expanding rapidly.

Автор: Frohlich
Название: The Local Cardiac Renin-Angiotensin Aldosterone System
ISBN: 1441905278 ISBN-13(EAN): 9781441905277
Издательство: Springer
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Описание: He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans.

Автор: Po Sing Leung
Название: The Renin-Angiotensin System: Current Research Progress in The Pancreas
ISBN: 9400733321 ISBN-13(EAN): 9789400733329
Издательство: Springer
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Описание: Highlighting the role local renin-angiotensin systems (RAS) play in pancreatic disease, this review presents the latest research advances in the field. These findings suggest both preventative measures and treatment for pancreatic disease.

Автор: Edward D. Frohlich; Richard N. Re
Название: The Local Cardiac Renin-Angiotensin Aldosterone System
ISBN: 1489981101 ISBN-13(EAN): 9781489981103
Издательство: Springer
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Описание: He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans.

Автор: D. Ganten; M.P. Printz; M.I. Phillips; B.A. Sch?lk
Название: The Renin Angiotensin System in the Brain
ISBN: 3642464580 ISBN-13(EAN): 9783642464584
Издательство: Springer
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Описание: The first publications on the presence of renin, angiotensino- gen and angiotensin-like material in brain tissue appeared about ten years ago. This coincided with the discovery of new biological actions of angiotensin in the brain and with the reinvestigation of already known central angiotensin effects. The possibility that angiotensin could be generated within the brain itself had therefore exciting implications. With the recent popularity of brain neuropeptides, interest in this area is even increasing. The discovery of renin-like activity as well as angiotensino- gen and angiotensin in the brain has led, admittedly by inductive inference, to the hypothesis of the existence of a complete endogenous renin-angiotensin system in the brain.1 For several years there was ardent discussion whether such a renin angiotensin system existed in the brain or not. Inductive inference always contains "an irrational element or a creative intuition".2In view of the biological relevance of a brain angiotensin system, deductive testing of the hypothesis was a worthwhile scientific project taken up by a number of investigators As a matter of principle it is not given to science, to reach either truth or falsity, scientific statements can only attain contmous degrees of probability whose unat- tamable upper and lower limits are truth or falsity. However, several of the early singular statements and results turned out to be reproducible and acceptable. The theory has thus so far passed its test and we have found no reason to discard it.

Автор: Hideshi Kobayashi; Yoshio Takei
Название: The Renin-Angiotensin System
ISBN: 3642647251 ISBN-13(EAN): 9783642647253
Издательство: Springer
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Цена: 46570.00 T
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Описание: The renin-angiotensin system and the mechanisms regulating this system developed during the adaptive evolution of verte- brates, along with many other systems involved in the in- tegrated survival of the organism.

Автор: Thatcher Sean E.
Название: The Renin-Angiotensin-Aldosterone System: Methods and Protocols
ISBN: 1493983733 ISBN-13(EAN): 9781493983735
Издательство: Springer
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Описание: Preface...
Table of Contents...
Contributing Authors...

1. A Brief Introduction into the Renin-Angiotensin-Aldosterone System: New and Old Techniques
Sean E. Thatcher

2. A Color Segmentation Based Method to Quantify Atherosclerotic Lesion Compositions with Immunostaining
Congqing Wu, Alan Daugherty, and Hong Lu

3. Assessment of Protein Carbonylation and Protein Tyrosine Phosphatase (PTP) Oxidation in Vascular Smooth Muscle Cells (VSMCs) using Immunoblotting Approaches
Sofia Tsiropoulou and Rhian M. Touyz

4. Methods for Studying the Role of RAAS in the Modulation of Vascular Repair-Relevant Functions of Stem/Progenitor Cells
Yagna P.R. Jarajapu

5. Use of a Fluorescent Substrate to Measure ACE2 Activity in the Mouse Abdominal Aorta
Yu Wang, Lisa A. Cassis, and Sean E. Thatcher

6. Measuring Blood Pressure using a Non-Invasive Tail Cuff Method in Mice
Yu Wang, Sean E. Thatcher, and Lisa A. Cassis

7. Blood Pressure Monitoring using Radio Telemetry Method in Mice
Yu Wang, Sean E. Thatcher, and Lisa A. Cassis

8. Characterization and Functional Phenotyping of Renal Immune Cells via Flow Cytometry
Nathan P. Rudemiller and Steven D. Crowley

9. Assessment of the Renin-Angiotensin System in Cellular Organelle: New Arenas for Study in the Mitochondria
Bryan A. Wilson and Mark C. Chappell

10. Comprehensive Assessments of Energy Balance in Mice
Justin L. Grobe

11. In Vitro Assays to Determine Smooth Muscle Cell Hypertrophy, Protein Content, and Fibrosis
Katherine J. Elliott and Satoru Eguchi

12. A New Mouse Model for Introduction of Aortic Aneurysm by Implantation of Deoxycorticosterone Acetate Pellets or Aldosterone Infusion in the Presence of High Salt
Shu Liu, Ming C. Gong, and Zhenheng Guo

13. Fluorescence-Based Binding Assay for Screening Ligands of Angiotensin Receptors
Maiia E. Bragina, Nikolaos Stergiopulos, and Rodrigo A. Fraga-Silva

14. A Primer to Angiotensin Peptide Isolation, Stability, and Analysis by Nano-Liquid Chromatography with Mass Detection
Mariola Olkowicz, Stefan Chlopicki, and Ryszard T. Smolenski

15. Analysis of Angiotensin Metabolism in the Kidney using Mass Spectrometry
Nadja Grobe and Khalid M. Elased

Автор: Anaberta Cardador-Martinez, Cristian Jimenez-Martinez
Название: Angiotensin-Converting Enzyme: Functions and Role in Disease
ISBN: 1536172499 ISBN-13(EAN): 9781536172492
Издательство: Nova Science
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Цена: 215410.00 T
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Описание: Angiotensin-converting enzyme (ACE) is a well-known zinc-metallopeptidase that converts angiotensin I to the potent vasoconstrictor angiotensin II and degrades bradykinin, a powerful vasodilator, both for the regulation of vascular tone and cardiac functions. Other natural substrates of ACE were identified broadening the functions of this enzyme within different physiological contexts such as neuronal metabolism, hematopoiesis, digestion, and reproduction. In this context, ACE has an essential role in diseases, for instance, hypertension, Alzheimers disease, oxidative stress, sperm maturation and fertility, intraocular pressure, bone metabolism, fibrillary glomerulonephritis, among others. This book describes the role of ACE as a part of the Renin-Angiotensin-System, on different metabolic processes related to some diseases, such as the examples already mentioned. Moreover, ACE is related to adipose tissue. The modulation of ACE can modulate hypertension and diseases related to this enzyme. Captopril is the first successful ACE inhibitor in the treatment of hypertension; however, it has adverse effects such as dry cough, dizziness, lightheadedness or loss of taste and others. The search for alternatives to Captopril has increased research on bioactive peptides. Then, several book chapters describe how ACE can be modulated by bioactive peptides, which are short amino acid sequences previously encrypted in whole proteins and liberated through the digestion process. Animal and vegetal proteins can be used as a source of bioactive peptides. Milk, milk-derived food products and lionfish are examples of animal proteins, while several legumes such as beans and peanuts are vegetable sources of bioactive peptides.

Автор: Naranjan S. Dhalla; Peter Zahradka; Ian M.C. Dixon
Название: Angiotensin II Receptor Blockade Physiological and Clinical Implications
ISBN: 1461376319 ISBN-13(EAN): 9781461376316
Издательство: Springer
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Цена: 279500.00 T
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Описание: The relationship between angiotensin II and hypertension was established in 1898 when angiotensin II was shown to modulate systemic blood pressure.

Автор: Donna H. Wang
Название: Angiotensin Protocols
ISBN: 1617371769 ISBN-13(EAN): 9781617371769
Издательство: Springer
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Цена: 172350.00 T
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Автор: Gerd Heusch; H. Grobecker; B.E. Strauer
Название: Angiotensin and the Heart
ISBN: 3798509360 ISBN-13(EAN): 9783798509368
Издательство: Springer
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Цена: 102480.00 T
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Описание: This volumes provides an overview of the most recent findings on the role of angiotensin and associated mediators in cardiovascular adaptation and disease, with a particular emphasis on the treatment of such diseases by ACE inhibitors.

Автор: Walmor C. DeMello; Edward D. Frohlich
Название: Renin Angiotensin System and Cardiovascular Disease
ISBN: 1607611856 ISBN-13(EAN): 9781607611851
Издательство: Springer
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Цена: 204040.00 T
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Описание: Covers aspects such as intracellular signaling, regulation of cell volume in the failing heart, the presence of an intracrine renin angiotensin system, and the influence of prorenin/renin, angiotensin II, angiotensin (1-7) and aldosterone. This book offers a review of the topics involving the renin angiotensin system and cardiovascular disease.