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Peptide Therapeutics, Jois


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Цена: 93160.00T
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Склад Америка: 171 шт.  
При оформлении заказа до: 2025-08-18
Ориентировочная дата поставки: конец Сентября - начало Октября
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Автор: Jois
Название:  Peptide Therapeutics
ISBN: 9783031045431
Издательство: Springer
Классификация:





ISBN-10: 3031045432
Обложка/Формат: Hardback
Страницы: 317
Вес: 0.66 кг.
Дата издания: 11.10.2022
Серия: AAPS Advances in the Pharmaceutical Sciences Series
Язык: English
Издание: 1st ed. 2022
Иллюстрации: 42 illustrations, color; 10 illustrations, black and white; ix, 317 p. 52 illus., 42 illus. in color.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: Fundamentals of design, development, and delivery
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: This book explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues. It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. The chapters are arranged in a linear fashion. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. Rather than covering extensive literature, the book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides. The book has nine chapters, and each chapter can be read as an independent unit on a particular concept.
Дополнительное описание: Basic Concepts of Design of Peptide based Therapeutics.- Computational Methods in Peptide Based Drug Design.- Synthesis, Purification, and Characterization of Linear and Cyclic Peptides.- Large Scale Synthesis of Peptides, Manufacturing Peptide Therapeuti


Synthetic peptide vaccine models

Автор: Karahan, Mesut
Название: Synthetic peptide vaccine models
ISBN: 0367473283 ISBN-13(EAN): 9780367473280
Издательство: Taylor&Francis
Рейтинг:
Цена: 132710.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes - the future of vaccination. The book illustrates the use of peptides vaccine systems and makes predictions of future development.

Peptide Synthesis

Автор: Waleed M. Hussein; Mariusz Skwarczynski; Istvan To
Название: Peptide Synthesis
ISBN: 1071602268 ISBN-13(EAN): 9781071602263
Издательство: Springer
Рейтинг:
Цена: 121110.00 T
Наличие на складе: Нет в наличии.
Описание: This book provides a variety of procedures for synthetically producing peptides and their derivatives, ensuring the kind of precision that is of paramount importance for successful synthesis. Numerous techniques relevant to drugs and vaccines are explored, such as conjugation and condensation methodologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Peptide Synthesis: Methods and Protocols serves as an essential guide to the many crucial processes that will allow researchers to efficiently prepare, purify, characterize, and use peptides for chemical, biochemical, and biological studies.

Peptide and Protein Drug Analysis

Название: Peptide and Protein Drug Analysis
ISBN: 0367399261 ISBN-13(EAN): 9780367399269
Издательство: Taylor&Francis
Рейтинг:
Цена: 65320.00 T
Наличие на складе: Нет в наличии.
Описание:

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design.
Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication.
Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis

  • discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability
  • analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology
  • examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods
  • highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry
  • demonstrates uses of unnatural mutagenesis and combinatorial chemistry
  • explores mass spectrometry, protein sequence, and carbohydrate analysis
  • illustrates bioassays and other new functional analysis methods
  • surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR)
  • addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells
  • reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering
  • and more!
    Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemis

  • Peptide Synthesis

    Автор: Hussein
    Название: Peptide Synthesis
    ISBN: 1071602292 ISBN-13(EAN): 9781071602294
    Издательство: Springer
    Рейтинг:
    Цена: 121110.00 T
    Наличие на складе: Нет в наличии.
    Описание: This book provides a variety of procedures for synthetically producing peptides and their derivatives, ensuring the kind of precision that is of paramount importance for successful synthesis.

    Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures

    Автор: Jaroslav Sebestik; Milan Reinis; Jan Jezek
    Название: Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures
    ISBN: 3709117038 ISBN-13(EAN): 9783709117033
    Издательство: Springer
    Рейтинг:
    Цена: 148010.00 T
    Наличие на складе: Есть у поставщика Поставка под заказ.
    Описание: Benefiting researchers in biochemistry and pharmacology, this book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies.

    Molecular Biotechnology of Fungal ?-Lactam Antibiotics and Related Peptide Synthetases

    Автор: Axel A. Brakhage
    Название: Molecular Biotechnology of Fungal ?-Lactam Antibiotics and Related Peptide Synthetases
    ISBN: 3642060358 ISBN-13(EAN): 9783642060359
    Издательство: Springer
    Рейтинг:
    Цена: 306530.00 T
    Наличие на складе: Есть у поставщика Поставка под заказ.
    Описание: With contribution by numerous experts

    Self-Assembling Peptide Systems in Biology, Medicine and Engineering

    Автор: A. Aggeli; N. Boden; Zhang Shuguang
    Название: Self-Assembling Peptide Systems in Biology, Medicine and Engineering
    ISBN: 9048157404 ISBN-13(EAN): 9789048157402
    Издательство: Springer
    Рейтинг:
    Цена: 213360.00 T
    Наличие на складе: Есть у поставщика Поставка под заказ.
    Описание: It has been long known that, in silk, polypeptides are assembled into- sheet structures which impart on the material its highly exploitable properties of flexibility combined with high tensile strength.

    De novo peptide design

    Название: De novo peptide design
    ISBN: 0323999174 ISBN-13(EAN): 9780323999175
    Издательство: Elsevier Science
    Рейтинг:
    Цена: 129130.00 T
    Наличие на складе: Есть у поставщика Поставка под заказ.
    Описание: 145 miles of lush, ever-green walking in North East Wales: featuring fourteen routes within the Clwydian Range and Dee Valley Area of Outstanding Natural Beauty, embracing the Clwydian and Berwyn Hills and Llantysilio Mountain; three walks on the North Wales coast between Great Orme and Point of Ayr; eleven rambles to the east of the River Conwy.

    Peptide Characterization and Application Protocols

    Автор: Gregg B. Fields
    Название: Peptide Characterization and Application Protocols
    ISBN: 161737637X ISBN-13(EAN): 9781617376375
    Издательство: Springer
    Рейтинг:
    Цена: 144410.00 T
    Наличие на складе: Есть у поставщика Поставка под заказ.
    Описание: This book is dedicated to the characterization of peptides and their applications for the study of biochemical systems. Part II, Application, presents a variety of specific applications for synthetic peptides. This book is an indispensable aid in the pursuit of new directions in peptide research.

    Peptide and Protein Engineering

    Автор: Olga Iranzo; Ana Cec?lia Roque
    Название: Peptide and Protein Engineering
    ISBN: 1071607197 ISBN-13(EAN): 9781071607190
    Издательство: Springer
    Рейтинг:
    Цена: 121110.00 T
    Наличие на складе: Нет в наличии.
    Описание: It opens with a section on chemical tools applied to the production or engineering of peptides and proteins, and concludes with a collection of chapters on biological approaches used to engineer structure and function in peptides and proteins.

    Cyclic Peptide Design

    Автор: Gilles Goetz
    Название: Cyclic Peptide Design
    ISBN: 1493995065 ISBN-13(EAN): 9781493995066
    Издательство: Springer
    Рейтинг:
    Цена: 121110.00 T
    Наличие на складе: Нет в наличии.
    Описание: This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance protein-protein recognition, and to build upon nature’s cyclic peptides and macrocycles. Chapters also cover key peptide screening and display strategies, as well as important synthetic approaches towards cyclic and helical peptides. Cyclic peptides have become of significant importance as chemical tools in biology and drug discovery, since this class of chemicals has become a credible alternative source of new drug leads on par with traditional small molecules. As a part of the Methods in Molecular Biology series, this collection includes the kind of detail and implementation advice to aid researchers in the field. Authoritative and cutting-edge, Cyclic Peptide Design serves as a critical resource and go-to reference for researchers within the pharmaceutical industry, as well as scientists and students in the bioorganic, medicinal, and natural product chemistry fields.

    Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification

    Автор: Wang Jianpeng
    Название: Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification
    ISBN: 366257134X ISBN-13(EAN): 9783662571347
    Издательство: Springer
    Рейтинг:
    Цена: 93160.00 T
    Наличие на складе: Есть у поставщика Поставка под заказ.
    Описание: This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.” This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.


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