Skeletal Muscle Stem Cells, Asakura

Автор: Ambers, Angie
Название: Forensic Genetic Approaches For The Identification Of Human Skeletal Remains
ISBN: 0128157666 ISBN-13(EAN): 9780128157664
Издательство: Elsevier Science
Рейтинг:
Цена: 132500.00 T
Наличие на складе: Поставка под заказ.
Описание: Unidentified human remains often are associated with tragic events, such as fires, terrorist attacks, natural disasters, war conflicts, genocide, airline crashes, homicide, and human rights violations under oppressive totalitarian regimes. In these situations, extensive damage to soft tissues often precludes the use of such biological samples in the identification process. In contrast, bone material is the most resilient, viable sample type for DNA testing. DNA recovered from bone often is degraded and in low quantities due to the effects of human decomposition, environmental exposure, and the passage of time. The complexities of bone microstructure and its rigid nature make skeletal remains one of the most challenging sample types for DNA testing. Specialized knowledge, equipment, and training are crucial to maximize success. Forensic Genetic Approaches for the Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies provides best practices on processing bone samples for DNA testing and to outline forensic genetics tools available for identification of skeletal remains in contemporary casework as well as in historical/archaeological investigations. Although the book focuses primarily on the use of DNA for direct identification or by kinship analyses, it also highlights complementary disciplines often used in concert with genetic data to make positive identifications, such as forensic anthropology, forensic odontology, and forensic art/sculpting

Автор: Childers Martin K.
Название: Regenerative Medicine for Degenerative Muscle Diseases
ISBN: 1493980017 ISBN-13(EAN): 9781493980017
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters navigate the nuances of these treatments in an array of contexts and biological systems. The topics covered include: How are urine cells from a patient with Duchenne muscular dystrophy transformed into beating heart cells? What can reprogrammed cells tell us about heart muscle failure? What do gene mutations mean for those born with a muscle disease? How are manufacturing methods applied to human stem cells? Does therapeutic exercise benefit those patients who receive engineered limb muscle? Is there practical advice about nutrition to enhance muscle function for the Duchenne patient? Can microRNAs be useful to regenerate diseased muscle? Regenerative Medicine for Degenerative Muscle Diseases is ideal for scientists and clinicians from varying disciplines in genetics, cell biology, virology, cell-based manufacturing, rehabilitation medicine, nutrition, veterinary medicine and neurosurgery. The reader will see how transformative changes occur in medicine that can powerfully impact the future for patients suffering from inherited disorders affecting muscles of the body, including the heart.