Computer Simulations of Aggregation of Proteins and Peptides, Li
Автор: Li Mai Suan, Kloczkowski Andrzej, Cieplak Marek Название: Computer Simulations of Aggregation of Proteins and Peptides ISBN: 1071615459 ISBN-13(EAN): 9781071615454 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Chapters discuss the relationship between protein misfolding and protein aggregation, methods of prediction of aggregation propensities of protein, peptides, protein structure, results of computer simulations of aggregation, and computational simulations focused on specific diseases such as Alzheimer`s, Parkinson`s, and preeclampsia.
Автор: Sandal, Massimo Название: Early Stage Protein Misfolding and Amyloid Aggregation ISBN: 012812251X ISBN-13(EAN): 9780128122518 Издательство: Elsevier Science Рейтинг: Цена: 196510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Early Stage Protein Misfolding and Amyloid Aggregation, Volume 329, the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology, including articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.
The series has a worldwide readership and maintains a high standard by publishing invited articles on important and timely topics as authored by prominent cell and molecular biologists.
Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A Volume 184, highlights many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. Emitting light is a fascinating photophysical phenomenon, its different forms have brought the attention of various disciplines of natural sciences for centuries. In the modern era of scientific generation, short-lived fluorescence light and its long-lived counterpart phosphorescence light has been employed for several chemo-sensing, bio-sensing, and bioimaging applications. The aggregation induced emission (AIE) phenomenon has appeared as a wand of modern science to convert aggregation-caused quenching (ACQ) materials into AIE active materials for a wide range of biomedical applications including biosensing, bioimaging and localization of molecules for better understanding of molecular mechanisms. This volume covers a wide range of topics which are not currently available in a single volume, including ACQ & AIE concept development; intracellular pH, temperature and viscosity sensing; imaging of cell membrane, lipid droplet, lysosome, and mitochondria; biosensing and Imaging of bacteria; nucleus and nucleic acid imaging.
Автор: Uversky Vladimir N., Fink Anthony Название: Protein Misfolding, Aggregation and Conformational Diseases / Part B: Molecular Mechanisms of Conformational Diseases ISBN: 038736529X ISBN-13(EAN): 9780387365299 Издательство: Springer Рейтинг: Цена: 243800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The second volume continues to fill the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.
Автор: Doglia Название: Protein Aggregation in Bacteria: Functional and Structural Properties of Inclusion Bodies in Bacterial Cells ISBN: 1118448529 ISBN-13(EAN): 9781118448526 Издательство: Wiley Рейтинг: Цена: 123500.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Focuses on the aggregation of recombinant proteins in bacterial cells in the form of inclusion bodies and on their use in biotechnological and medical applications. This title provides a large overview of protein folding and aggregation, including cell biology and methodological aspects.
Автор: David Eliezer Название: Protein Amyloid Aggregation ISBN: 1493950053 ISBN-13(EAN): 9781493950058 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This detailed volume focuses on methods for the characterization of aggregation processes that lead to the formation of amyloid fibrils and amyloid oligomers which feature in the etiology of a variety of human disorders collectively known as amyloidoses.
Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B Volume 185, presents many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. Fluorescence-based monitoring and diagnosis platforms furnish extensive insight into the molecular mechanisms of cellular processes and precisely guiding therapeutics. Traditional/conventional fluorophores are exhibiting high emission in the solution state and losses their emission on aggregation and solid forms. Loss of emission at aggregation and solid forms limits conventional fluorophores utilization in monitoring and diagnosis of biological processes. The AIE molecular system emerged as an alternative sophisticated platform to over the limitations of conventional organic/inorganic fluorophores. This volume offers various topics, including tissue & protein fibrils imaging by AIE active molecules; theranostic and photodynamic therapy applications of AIE materials for cancer cell treatment; AIE active polymers and MOF materials for biological applications.
Автор: Tavassoli Ali Название: Inhibitors of Protein-Protein Interactions: Small Molecules, Cyclic Peptides, Macrocycles and Antibodies ISBN: 178801569X ISBN-13(EAN): 9781788015691 Издательство: Royal Society of Chemistry Рейтинг: Цена: 223870.00 T Наличие на складе: Нет в наличии. Описание: Illustrated throughout with successful case studies, this book provides a holistic, cutting-edge view of the subject area and is ideal for chemical biologists and medicinal chemists interested in developing PPI inhibitors.
Автор: Langel, Ulo , Cravatt, Benjamin F. , Graslund, A Название: Introduction to Peptides and Proteins ISBN: 0367384876 ISBN-13(EAN): 9780367384876 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Human cells produce at least 30,000 different proteins. Each has a specific function characterized by a unique sequence and native conformation that allows it to perform that function. While research in this post-genomic era has created a deluge of invaluable information, the field has lacked for an authoritative introductory text needed to inform researchers and students in all of those fields now concerned with protein research.
Introduction to Peptides and Proteins brings together some of the most respected researchers in protein science to present a remarkably coherent introduction to modern peptide and protein chemistry. The first sections of the book delve into -
Basic peptide and protein science from assembly through degradation
Traditional and emerging research methods including those used in bioinformatics and proteomics
New computational approaches and algorithms used to find patterns in the vast data collected by sequencing projects
After providing a foundation in tools and methods, the authors closely examine six protein families, including representative classes such as enzymes, cell-surface receptors, antibodies, fibrous proteins, and bioactive peptide classes. They concentrate on biochemical mechanisms and where possible indicate therapeutic or biotechnical possibilities.
Then focusing on clinical aspects, the authors investigate misfolding as found in prion diseases, miscleavage as found in Alzheimer's, and mis-sequencing as found with some cancers. Drawing from some of their own research, the authors summarize recent achievements and emerging applications. They discuss the use of proteins and peptides as drugs and the solid-phase synthesis required for drug production. They also look at the use of peptides as functional biomolecules and research tools.
No longer just th
Автор: Hovgaard, Lars Название: Pharmaceutical Formulation Development of Peptides and Proteins ISBN: 1439853886 ISBN-13(EAN): 9781439853887 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Langel, Ulo Название: Introduction to Peptides and Proteins ISBN: 1420064126 ISBN-13(EAN): 9781420064124 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
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