Jeltsch DNA Methyltransferases - Role and Function 9783319828701

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Автор: Jeltsch
Название: DNA Methyltransferases - Role and Function
ISBN: 9783319828701
Издательство: Springer
Классификация:

Медицинская генетика

Клеточная биология (цитология)

ISBN-10: 3319828703
Обложка/Формат: Soft cover
Страницы: 535
Вес: 1.11 кг.
Дата издания: 20.07.2018
Серия: Advances in Experimental Medicine and Biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 60 tables, color; 57 illustrations, color; 4 illustrations, black and white; viii, 535 p. 61 illus., 57 illus. in color.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: DNA methyltransferases are important enzymes in a broad range of organisms. Dysfunction of DNA methyltransferases in humans leads to many severe diseases, including cancer. This book focuses on the biochemical properties of these enzymes, describing their structures and mechanisms in bacteria, humans and other species, including plants, and also explains the biological processes of reading of DNA methylation and DNA demethylation. It covers many emerging aspects of the biological roles of DNA methylation functioning as an essential epigenetic mark and describes the role of DNA methylation in diseases. Moreover, the book explains modern technologies, like targeted rewriting of DNA methylation by designed DNA methyltransferases, as well as technological applications of DNA methyltransferases in DNA labelling. Finally, the book summarizes recent methods for the analysis of DNA methylation in human DNA. Overall, this book represents a comprehensive state-of-the-art- work and is a must-have for advanced researchers in the field of DNA methylation and epigenetics.
Дополнительное описание: Mechanisms and biological roles of DNA methylation and DNA methyltransferases – from past achievements to future challenges.- DNA and RNA pyrimidine nucleobase alkylation at the carbon-5 position.- Bacterial DNA methylation and methylomes.- Domain structu

DNA Methyltransferases - Role and Function, Jeltsch