Автор: Sun Jun Название: Inflammation, Infection, and Microbiome in Cancers: Evidence, Mechanisms, and Implications ISBN: 3030679500 ISBN-13(EAN): 9783030679507 Издательство: Springer Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers.Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease.
Автор: Sabu Thomas Название: Human Microbiome ISBN: 9811676712 ISBN-13(EAN): 9789811676710 Издательство: Springer Цена: 130430.00 T Наличие на складе: Поставка под заказ. Описание: The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. This book talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.
Автор: Jun Sun; Pradeep K. Dudeja Название: Mechanisms Underlying Host-Microbiome Interactions in Pathophysiology of Human Diseases ISBN: 1493975331 ISBN-13(EAN): 9781493975334 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes. In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.
The Human Microbiome in Early Life, Implications to Health and Disease presents recent research advances that have highlighted the significance of early life, possibly beginning before birth, in the establishment of both the microbiome and its role in health and disease. The book reviews current knowledge on the origins of the human microbiota in early life, presents exposures which may disturb normal microbial colonization, and covers their implications to the risk of disease. Finally, emerging means to modify the early human microbiome to improve health are discussed.
Автор: Jun Sun; Pradeep K. Dudeja Название: Mechanisms Underlying Host-Microbiome Interactions in Pathophysiology of Human Diseases ISBN: 1493985132 ISBN-13(EAN): 9781493985135 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes. In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.
Название: Human-gut microbiome ISBN: 032391313X ISBN-13(EAN): 9780323913133 Издательство: Elsevier Science Рейтинг: Цена: 129130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines the ways individuals in the US and Russia consume and construct collective memories of political events via a reestablished Cold War-like narrative in both media systems. The book contextualizes the rebirth of this phenomenon via seven political events involving Russia, examining the contemporary role of conscious media distrust in subconscious psychological processes.
Автор: Rhodes, Rosamond; Gligorov, Nada; Schwab, Abraham Название: The Human Microbiome ISBN: 0199829411 ISBN-13(EAN): 9780199829415 Издательство: Oxford Academ Рейтинг: Цена: 74970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Human microbiome research has revealed that legions of bacteria, viruses, and fungi live on our skin and within the cavities of our bodies. New knowledge from these recent studies shows that humans are superorganisms and that the microbiome is indispensible to our lives and our health. This volume explores some of the science on the human microbiome and considers the ethical, legal, and social concerns that are raised by this research.
Автор: Patricia Marques Название: Human Microbiota and Microbiome ISBN: 1773611739 ISBN-13(EAN): 9781773611730 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 133760.00 T Наличие на складе: Невозможна поставка. Описание: Provides an introduction and description of the Human Microbiome Project. The book covers the microbiota and microbiome of specific body fluids, and tissues (oral and nasopharyngeal sites, lungs, skin, gastrointestinal tract, vagina and others), in vitro and in vivo models for the study of the Human Microbiota and Microbiome, and the metabolome.
Автор: Bramha Chari P. Veera Название: Microbiome in Human Health and Disease ISBN: 9811631557 ISBN-13(EAN): 9789811631559 Издательство: Springer Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is intended for periodontal residents and practicing periodontists who wish to incorporate the principles of moderate sedation into daily practice. Comprehensive airway management and rescue skills are then documented in detail so that the patient may be properly managed in the event that the sedation progresses beyond the intended level.
An essential introduction to microbiome science, a new cutting-edge discipline that is transforming the life sciences
This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. Resident microbes in healthy animals--including humans-can dictate many traits of the animal host. This animal microbiome is a second immune system conferring protection against pathogens; it can structure host metabolism in animals as diverse as reef corals and hibernating mammals; and it may influence animal behavior, from social recognition to emotional states. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet, and have contributed to animal diversification over long evolutionary timescales. Drawing on concepts and data across a broad range of disciplines and systems, Angela Douglas provides a conceptual framework for understanding these animal-microbe interactions while shedding critical light on the scientific challenges that lie ahead. Douglas explains why microbiome science demands creative and interdisciplinary thinking-the capacity to combine microbiology with animal physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science. An essential introduction to a cutting-edge field that is revolutionizing the life sciences, this book explains why microbiome science presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for many medical conditions and new strategies for pest control.
Автор: Georgios N. Belibasakis; George Hajishengallis; Na Название: Oral Mucosal Immunity and Microbiome ISBN: 3030285235 ISBN-13(EAN): 9783030285234 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems.
In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.
Автор: Xia Yinglin, Sun Jun, Chen Ding-Geng Название: Statistical Analysis of Microbiome Data with R ISBN: 9811315337 ISBN-13(EAN): 9789811315336 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Chapter 1: Introduction to R, RStudio and ggplot2 1.1 Introduction to R 1.2 Introduction to RStudio 1.3 Introduction to ggplot2 1.4 Introduction to R Packages for Microbiome Data Chapter 2: What are Microbiome Data?2.1 Phylogenetics--The Basics 2.2 What Microbiome Data Look Like? 2.2.1 Basic Data Structure and Format of Microbiome Data 2.2.2 OUT Table2.2 3 Response Variables and Covariates2.3 Some Specific Features of Microbiome Data Chapter 3: Bioinformatic and Statistical Analyses of Microbiome Data 3.1 Overview of Bioinformatic Analysis 3.1.1 Taxonomic Diversity: from the 16S-based Approach 3.1.2 Taxonomic Profiling of Shotgun Metagenomes3.1.3 Introduction to Bioinformatic toolso QIIME o Mothuro 16S rRNA Gene Sequence Data Analysis using QIIME and Mothuro Other Biostatistics Tools3.2 Statistical Analysis of Microbiome Community Composition 3.2.1 Alpha Diversity Analysis and Statistical Measurements 3.2.2 Beta Diversity Analysis and Statistical Measurements3.3 Multivariate Statistical Techniques 3.3.1Data Visualization: Principal Component and Principal Coordinates Analyses 3.3.2 Classification and Clustering with Visualization 3.4 Hypothesis Testing and Statistical Modeling 3.4.1 Statistical Testing of Microbiome Community 3.4.2 Multivariate Statistical Methods and Modeling of Microbiome Community and Environmental Covariates3.4.3 Mediational and Longitudinal Microbiome Data Analysis3.4.4 Host Interactions and Interventions3.4.5 Mediation Analysis and Longitudinal Analysis 3.5 Multiple Comparisons and Testing Correlation 3.6 Correlation Analysis of Microbiome Community and Environmental Covariates Chapter 4: Power and Sample Size Calculation in Hypothesis Testing Microbiome Data4.1 Statistical Hypothesis Testing and Power Analysis 4.1.1 Hypothesis Testing 4.1.2 Power Analysis and Sample Size Calculation4.2 Comparing Diversity or a Taxon of Interest between Two Groups 4.2.1 Hypotheses and Basic Power and Sample Size Formulas4.2.2 Diversity Data for Vitamin D and Vitamin D Receptor Study4.2.3 Theory of Power for a Test for Comparing Proportions4.2.4 Power of Fisher's Exact Test for Comparing Proportions4.2.5 R Function power.t.test4.3 Comparing Diversity across More than Two Groups 4.3.1 Hypotheses and Theory of Power for One-Way ANOVA4.3.2 Examples4.3.2 R Function pwr.avova.test4.4 Comparing the Frequency of all Taxa across Groups4.4.1 Hypotheses Testing and Power and Sample Size Calculations for Comparing all Taxa4.4.2 Dirichlet-multinomial model in Power and Sample Size Analyses4.4.3 Power and Size Calculations using HMP Package4.5 Power and Sample Size Estimation using Pairwise Distances and PERMANOVA 4.5.1 PERMANOVA and Estimation of PERMANOVA Power 4.5.2 Examples using micropower Package4.6 Power Calculations using ANOSIM Package Chapter 5: Microbiome Data Management5.1 Data Importing and Merging datasets or components 5.1.1 Importing the Output from QIIME 5.1.2 Importing the Output from mothur&
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